Extended Data Fig. 2: Gender-based analysis of transcriptome and quantitative proteome of young and old monkey skeletal muscle.
From: SIRT5 safeguards against primate skeletal muscle ageing via desuccinylation of TBK1
a. Ring plots showing upregulated and downregulated DEGs in male old versus male young monkey skeletal muscles, and female old versus female young monkey skeletal muscles. b. Representative GO terms and pathways for upregulated and downregulated DEGs in male old versus male young monkey skeletal muscles, and female old versus female young monkey skeletal muscles. c. Ring plots showing upregulated and downregulated DEPs in male old versus male young monkey skeletal muscles, and female old versus female young monkey skeletal muscles. d. Representative GO terms and pathways for upregulated and downregulated DEPs in male old versus male young monkey skeletal muscles, and female old versus female young monkey skeletal muscles. e. Lollipop plots showing the shared upregulated and downregulated GO terms and pathways for upregulated and downregulated DEGs and DEPs in male old versus male young monkey skeletal muscles, and female old versus female young monkey skeletal muscles. Hypergeometric tests were performed in b, d and e. mkMuscle, monkey muscle.
