Fig. 1: Myelin water fraction changes in white matter regions after running a marathon.
From: Reversible reduction in brain myelin content upon marathon running
Top, slab volumes (average intensity projection) of MWF maps from five consecutive coronal slices centred in motor descending pathways from an individual before the marathon (pre-run), two days after the marathon (post-run, 2 d) and two weeks after the marathon (post-run, 2 w), as well as after two months (2 m) of recovery. Bottom, histogram with mean ± s.e.m. values from all subjects (n = 10 for pre- and post-run, n = 6 for recovery) showing significant MWF reduction in white and grey matter areas 1–2 days after the marathon, and subsequent recovery to pre-run levels during two months of recovery. Individual data points for each histogram bar (n = 20 for pre- and post-run, n = 12 for recovery) originated from the two hemispheres in each subject. Notice that values return to pre-run levels in all areas. *P < 0.05 and ***P < 0.005, one-tailed paired Student’s t-test. See Extended Data Fig. 4 for exact P values and its Source Data for individual data points.
