Extended Data Fig. 4: Distinct correlation patterns between bacterial taxa and long-chain acylcarnitines in non-lean vs. lean MASLD.

The analysis includes bacterial taxa with at least four instances of absolute correlation differences greater than 0.3 and acylcarnitines. Dot size represents the magnitude of the absolute difference in correlations between non-lean and lean MASLD cases (that is, |⍴(bacteria and acylcarnitines) for non-lean - ⍴(bacteria and acylcarnitines) for lean|). Dot colour reflects the directionality of the correlations in each group. This visualization highlights the interplay between microbes and acylcarnitines (based on chain length) across MASLD phenotypes.