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This Collection supports and amplifies research related to SDG3.
Viral hemorrhagic fever (VHF) viruses encompass some of the most deadly viruses known to man, and pose major public health threats throughout various parts of the world. Correspondingly, many of the viruses that fall into this group have to be handled under maximum biocontainment conditions (i.e. BSL4 or equivalent), and/or are among the priority infectious diseases currently considered to represent the greatest risk to public health by the WHO. VHF viruses include the filoviruses (e.g. Ebola and Marburg virus), a large number of arenaviruses (e.g. Lassa and Junín virus), the nairovirus Crimean-Congo Hemorrhagic Fever virus, hantaviruses (e.g. Hantaan virus), the phenuivirus Rift Valley fever virus, and the lesser-known peribunyavirus Ngari virus, as well as various flaviviruses (e.g. Omsk hemorrhagic fever virus, Kyasanur forest disease virus, Dengue virus, and Yellow fever virus).
Encouragingly, the last years have seen tremendous progress in our understanding of the biology of these viruses, and for some of these viruses this research has even resulted in countermeasures now being available for deployment during virus outbreaks. This collection invites original research on all aspects related to the study of viral hemorrhagic fever virus, including their molecular biology, virus-host interactions, pathogenesis, countermeasure development and testing, clinical aspects and virus ecology, as well as technical developments related to work on these viruses. This will be complemented by invited reviews on emerging topics regarding these viruses by experts in the field.