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Ciofani et al., discuss the unique medical and pharmaceutical challenges in maintaining and supplying medical care for crews involved for human space missions beyond Low Earth Orbit, such as to the Moon and Mars. They highlight opportunities for repurposing existing innovative technologies and biomedical advances to support crew health during long-duration missions.
Gries et al. comprehensively review the pathophysiological link between MASLD and the various heart failure subtypes. Their discussion highlights preventative and therapeutic co-management strategies for patients with both conditions.
Gupta et al. discuss the epidemiology and burden of major circulating arboviral diseases in India, touching on diagnosis, treatment, and preventative measures. They highlight key research and policy gaps, along with direction for future research, to improve surveillance and control measures.
Kohabir et al. review recent advances in CRISPR-based diagnostics aimed at achieving single-nucleotide fidelity for clinical applications. By dissecting strategies in gRNA design, effector selection, and reaction conditions, the authors highlight how these innovations can support precise and accessible genetic testing at the point-of-care.
Boeckmans et al. discuss the importance of healthcare providers fully engaging with people with Metabolic dysfunction-associated steatotic liver disease (MASLD) and actively working with them to improve their metabolic health. They propose areas to focus on and provide a practical guide to healthcare practitioners in this area.
Eisinger-Mathason et al. examine how data linkage transforms healthcare research by integrating diverse datasets. They also discuss privacy-preserving methods and challenges related to data quality and privacy.
