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  • It is challenging to separate middle-sized molecules from complex mixtures using traditional molecular sieves. Here a metal–organic framework has been developed with dynamic molecular pockets that can adjust and accommodate alkynes preferentially, realizing efficient production of high-purity ethylene from its mixtures with alkynes regardless of their molecular sizes.

    • Heng Zeng
    • Xiao-Jing Xie
    • Dan Li
    Article
  • Protein engineering is a powerful tool to create new proteins with useful functions and behaviors, but it is slow, laborious and requires specialized knowledge, limiting its broad application. Here, the authors present a system that combines AI and experimental automation to autonomously engineer proteins without human intervention.

    • Jacob T. Rapp
    • Bennett J. Bremer
    • Philip A. Romero
    ArticleOpen Access
  • Developing biointerfaces that combine the advantages of both monolithic and focal elements remains challenging. Now, a hydrogel that releases surface-modified granules and shows biointerface transition capability has been developed. This granule-releasing hydrogel manages colitis, accelerates wound healing, and facilitates cardiac tissue regeneration and mapping of cardiac activity with bioelectronic devices.

    • Jiuyun Shi
    • Yiliang Lin
    • Bozhi Tian
    Article
  • Carbon–carbon bonds are ubiquitous in lignin, limiting monomer yields from current depolymerization strategies mainly targeting C–O bonds. Now, a bifunctional hydrocracking approach uses a Pt/zeolite catalyst to break C–C bonds in lignin waste, achieving monocyclic hydrocarbon yields up to 54 C%.

    • Zhicheng Luo
    • Chong Liu
    • Emiel J. M. Hensen
    Article
  • A flexible hemline-shaped microfiber featuring periodic parallel microcavities with sharp edges and wedges was developed using microfluidics to achieve unidirectional liquid transport along arbitrary pathways.

    • Chaoyu Yang
    • Yunru Yu
    • Yuanjin Zhao
    Article

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