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  • Rapid identification of pathogenic viruses remains a critical challenge. A recent study advances this frontier by demonstrating a fully integrated memristor-based hardware system that accelerates genomic analysis by a factor of 51, while reducing energy consumption to just 0.2% of that required by conventional computational methods.

    • Kaichen Zhu
    • Mario Lanza
    News & Views
  • A recent study proposed ZeoBind, an AI-accelerated workflow enabling the discovery and experimental verification of hits within chemical spaces containing hundreds of millions of zeolites.

    • David Balcells
    News & Views
  • A recent study sought to replicate published experimental research using large language models, finding that human behavior is replicated surprisingly well overall, but deviates in important ways that could lead social scientists astray.

    • Austin van Loon
    • Zoe Heidenry
    News & Views
  • An artificial neural network-based strategy is developed to learn committor-consistent transition pathways, providing insight into rare events in biomolecular systems.

    • Thorben Fröhlking
    • Simone Aureli
    • Francesco Luigi Gervasio
    News & Views
  • A recent study introduces a neural code conversion method that aligns brain activity across individuals without shared stimuli, using deep neural network-derived features to match stimulus content.

    • Ma Feilong
    • Yuqi Zhang
    News & Views
  • A framework with large language models is proposed to predict disease spread in real-time by incorporating complex, multi-modal information and using a artificial intelligence–human cooperative prompt design.

    • Narendra M. Dixit
    News & Views
  • A new framework disentangles the nature of disruption in science, revealing how rare but persistent breakthroughs shake the foundations of research fields while remaining central to future work.

    • Russell J. Funk
    • Xiangting Wu
    News & Views
  • A recent study assesses bias in artificial intelligence (AI)-generated medical language to find differences in age, sex, and ethnicity. An optimization technique is proposed to improve fairness without sacrificing performance.

    • Yumeng Zhang
    • Jiangning Song
    News & Views
  • The continuous drive for efficiency in high-performance computing has led to the development of new frameworks aimed at optimizing large-scale simulations. One such advancement is dynamic block activation, a method designed to significantly accelerate continuum models while making full use of modern computing architectures that combine central processing units and graphics processing units.

    • Nicolò Scapin
    News & Views
  • Predicting stable crystal structures for complex systems that involve multiple elements or a large number of atoms presents a formidable challenge in computational materials science. A recent study presents an efficient crystal-structure search method for this task, utilizing symmetry and graph theory.

    • Yanchao Wang
    News & Views
  • Identifying promising synthesis targets and designing routes to their synthesis is a grand challenge in chemistry and materials science. Recent work employing machine learning in combination with traditional approaches is opening new ways to address this truly Herculean task.

    • J. C. Schön
    News & Views
  • A recent study demonstrates through numerical simulations that implementing large language models based on sparse mixture-of-experts architectures on 3D in-memory computing technologies can substantially reduce energy consumption.

    • Anand Subramoney
    News & Views
  • By combining several probabilistic AI algorithms, a recent study demonstrates experimentally that the inherent noise and variation in memristor nanodevices can be exploited as features for energy-efficient on-chip learning.

    • Damien Querlioz
    News & Views
  • An extensive audit of large language models reveals that numerous models mirror the ‘us versus them’ thinking seen in human behavior. These social prejudices are likely captured from the biased contents of the training data.

    • Germans Savcisens
    News & Views
  • Today’s high-performance computing systems are nearing an ability to simulate the human brain at scale. This presents a new challenge: going forward, will the bigger challenge be the brain’s size or its complexity?

    • Felix Wang
    • James B. Aimone
    News & Views

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