Articles

Two-dimensional boridene supports neuromorphic optoelectronic computing through anomalous electrical anisotropy. Its low-temperature deposition supports back-end-of-line-compatible fabrication of twelve-inch wafer arrays.

A metasurface-based spatial light modulator brings the pixel size down to the submicrometre scale while demonstrating real-time complex-amplitude holography, three-dimensional focusing and beam steering over a ±20.6° field of view in the visible.

Operating a photonic chip that integrates quantum dots with lithium niobate resonators at an exceptional point allows for spontaneous single-photon emission with an exceptional-point-induced transparency window, a squared-Lorentzian line shape or a Fano-asymmetric line shape.

Biodegradable enzymatic microbubble robots self-propel in urea, are magnetically or chemotactically guided, provide ultrasound imaging and enhance intratumoural drug delivery with focused ultrasound.

Scanning nitrogen-vacancy microscopy unveils super-moiré spin textures emerging in twisted double-bilayer CrI₃ and provides real-space evidence of antiferromagnetic Néel-type skyrmions spanning multiple moiré cells.

A modular, point-of-care device combining hemispheric plasmonic nanoarrays and automated microfluidics enables nucleic acid amplification and metabolic cell viability assay for rapid bacterial identification and antibiotic susceptibility testing.

Cryogenic transport measurements of CsV₃Sb₅ nanobeams show a zero-field Josephson diode effect and radio-frequency rectification with power-dependent quantized voltage output.

Personalized nanovaccines derived from autologous tumour cells and engineered to display dendritic cell-like features enhance immune activation and prevent postoperative metastatic cancer in preclinical models.

Superlubric arrays of double-bilayer graphene enable elastically coupled switching between Bernal and rhombohedral graphene polytypes under shear forces below 1 nN with an estimated energy cost of less than 1 fJ per switching event.

Focused ion beam-based nanofabrication enables the production of 3D helical devices from single-crystalline Co₃Sn₂S₂. The resulting chiral geometry-driven symmetry breaking produces a diode-like electrical response in transport measurements.

Engineered mucus-tethering bispecific nanobodies neutralize and entrap viruses to enhance mucosal immunity, preventing influenza infection and limiting SARS-CoV-2 transmission.

Strongly enhanced optical nonlinearities and an ultrafast transition from coherent to incoherent polariton excitations are demonstrated by coupling an atomically thin WS₂ layer to a plasmonic nanostructure using ultrafast multidimensional spectroscopy.

A lipid nanoparticle that delivers mRNA encoding for regenerative factors to the endometrium with high specificity restores implantation rates in a murine model of endometrial injury with potentially improved safety.

A label-free, DNA-based proximity ligation assay that uses ligatable staple pairs enables the longitudinal quantification of DNA origami structural stability dynamics in vivo, with single-helix resolution for both wireframe and lattice designs.

Negative refraction—light bending opposite to conventional refraction—and a hyperlens effect is observed in an excitonic system in the two-dimensional magnet CrSBr. The effect is mediated by the magnetic order of the material.

Highly ionically conductive and flexible solid-state composite battery electrolytes are engineered by alternately stacking inorganic Li_xM_yPS₃ (M = Cd or Mn) nanosheets with lithium-containing organic polymers in a perpendicular orientation to the surface of the electrodes.

By leveraging the superconducting phase transition of Nb, a near-field thermal diode that operates near liquid helium temperature is demonstrated.

Nanoparticles sensing glycosaminoglycan loss in osteoarthritis enable disease-severity-responsive delivery of ghrelin messenger RNA to cartilage lesions, reducing cartilage damage, bone thickening and pain in animal models.

An ultrasmall particle adjuvant therapy reprogrammes the tumour microenvironment of a resistant melanoma to a pro-inflammatory state, enhances antitumour immunity and synergizes with immune checkpoint inhibitors to prolong survival in murine models.

A virus-mimicking micelle selectively delivers drugs to diseased chondrocytes in osteoarthritis, significantly alleviating disease progression in mouse and sheep models.