Articles

‘Ultrathin’ gold interlayers are shown to form nanoparticles that balance optical losses and electrical contact, enabling efficient perovskite–perovskite integration for scalable and durable triple-junction photovoltaics.

By carefully dispersing small amounts of Ir into the RuO₂ lattice, a Ru₆IrOₓ catalyst reduces Ir usage by 80% while still running stably for over 1,500 h at 2 A cm⁻² in both laboratory- and industrial-scale proton-exchange membrane water electrolysers.

A spatiotemporally adaptive targeting strategy ensures sequentially reprogramming metabolism of inflammatory macrophages and senescent stem cells via intracellular NAD⁺ replenishment, accelerating bone and skin tissue regeneration.

A hydrogel matrix fabricated by cryo-photocrosslinking enables the direct, scalable isolation of extracellular vesicles from diverse biofluids without preprocessing, allowing for in-gel preservation for long-term storage and biomedical applications.

Covalent DNA tagging of cysteine residues enhances protein capture and slows the passage of proteins through a silicon nitride nanopore, yielding distinctive electrical signatures for the rapid classification of proteins.

Integrated scanning probe techniques in combination with first-principles theory unveil the crystallization of electron polarons into quasi-one-dimensional polaron superlattices in individual polypentacene molecules.

Memristor arrays based on molecular crystal with van der Waals-linked cages are fabricated, enabling ultralow energy switching, high endurance and seamless integration into neuromorphic computing hardware.

Self-assembled multidomain supramolecular peptide hydrogels that engage in dynamic covalent bonding with small-molecule drugs and biologics are shown to offer sustained release, extend the activity, and maintain safe and potent drug levels in vivo.

Metasurface optical modulators with silicon/organic hybrid nanostructures are demonstrated to achieve >Gbit s⁻¹ data modulation with complementary metal–oxide–semiconductor-compatible driving voltages.

A topological phase of light emerges in dynamically driven nonlinear photonic crystals.

Quantum emitters respond to weak near-field coupling with topological photonic waveguides, revealing polarization and spectral reshaping.

Through binding mitochondrial ATP synthase, engineered nanomedicines rejuvenate aged bone stem cells and restore osteogenesis, reversing osteoporosis in mice and offering a potential senolytic therapy for skeletal ageing.

Acoustically activatable nanocarriers made by incorporating 5% sucrose into liposomes release drug with low-intensity ultrasound, providing a readily clinically translatable system for both central and peripheral noninvasive neuromodulation.

A single adaptive neuromorphic vision device is reported to emulate four high-order visual neuronal dynamics, enabling a highly efficient and compact artificial general vision intelligence system towards dynamic scenarios.

Preventing endosomal damage sensing or using lipids that create reparable endosomal holes reduces inflammation caused by RNA–lipid nanoparticles while enabling high RNA expression.

Polariton-mediated photochemical charge transfer can be identified and quantified in a properly designed photonic system using momentum-resolved ultrafast optical techniques.

Preventing endosomal damage sensing or using lipids that create reparable endosomal holes reduces inflammation caused by RNA-lipid nanoparticles while enabling high RNA expression.

Room-temperature nonlinear Hall effect has been observed in wafer-scale (001)-oriented SnTe thin films, enabling wireless, ultrabroadband and low-power rectification at zero electrical bias and zero magnetic field.

Single, self-amplifying RNA molecules condensed by an oppositely charged polyelectrolyte self-assemble into compact globular nanoparticles that can be used as vaccines to generate potent immunological responses at low doses.

Intravenous interleukin-10 messenger RNA nanoparticles enhance immune responses in preclinical tumour models, promoting T cell activity and dendritic cell maturation, as well as improving survival and tumour eradication rates, with limited interleukin-10-induced systemic toxicity.