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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

This article reviews how the identification of Snail, ZEB and some basic helix–loop–helix (bHLH) factors as inducers of epithelial–mesenchymal transition (EMT) and potent repressors of E cadherin expression has opened new avenues for cancer research with potential clinical implications.

Héctor Peinado
David Olmeda
Amparo Cano
Reviews17 May 2007
Nature Reviews Cancer

Volume: 7, P: 415-428
Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin

Single immune checkpoint blockade has shown limited activity in patients with neuroendocrine neoplasms (NENs). Here the authors report the results of a phase II clinical trial of durvalumab (anti-PD-L1) and tremelimumab (anti CTLA-4) in patients with advanced NENs of gastroenteropancreatic and lung origin.

J. Capdevila
J. Hernando
J. L. Manzano
ResearchOpen Access23 May 2023
Nature Communications

Volume: 14, P: 1-8
Dissociable mechanisms govern when and how strongly reward attributes affect decisions

Maier, Raja Beharelle et al. provide a computational model of the decision process that quantifies the temporal dynamics of weighing different attributes. Their time-varying drift diffusion model reveals latent individual differences in decision-making.

Silvia U. Maier
Anjali Raja Beharelle
Todd A. Hare
Research01 Jun 2020
Nature Human Behaviour

Volume: 4, P: 949-963
Determining factors and alternatives for the career development of women executives: a multicriteria decision model

María Luz Martín-Peña
Cristina R. Cachón-García
María A. De Vicente y Oliva
ResearchOpen Access21 Jul 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-15
Case–Control Genome-Wide Association Study of Persistent Attention-Deficit Hyperactivity Disorder Identifies FBXO33 as a Novel Susceptibility Gene for the Disorder

Cristina Sánchez-Mora
Josep A Ramos-Quiroga
Marta Ribasés
Research06 Oct 2014
Neuropsychopharmacology

Volume: 40, P: 915-926
ADHD, Smoking Withdrawal, and Inhibitory Control: Results of a Neuroimaging Study with Methylphenidate Challenge

Maggie M Sweitzer
Scott H Kollins
F Joseph McClernon
Research20 Oct 2017
Neuropsychopharmacology

Volume: 43, P: 851-858
Stromal disrupting effects of nab-paclitaxel in pancreatic cancer

R Alvarez
M Musteanu
M Hidalgo
ResearchOpen Access01 Aug 2013
British Journal of Cancer

Volume: 109, P: 926-933
A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer

Vera Gorbunova
J. Thaddeus Beck
Jordan D. Berlin
ResearchOpen Access11 Dec 2018
British Journal of Cancer

Volume: 120, P: 183-189
Erratum: Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism

A Christakou
C M Murphy
K Rubia
Amendments and Corrections24 Jan 2013
Molecular Psychiatry

Volume: 18, P: 264
Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism

A Christakou
C M Murphy
K Rubia
ResearchOpen Access31 Jan 2012
Molecular Psychiatry

Volume: 18, P: 236-244
Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis

Yanli Zhang-James
Emily C. Helminen
Stephen V. Faraone
ResearchOpen Access01 Feb 2021
Translational Psychiatry

Volume: 11, P: 1-9
Correction: A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer

Vera Gorbunova
J. Thaddeus Beck
Jordan D. Berlin
Amendments and CorrectionsOpen Access26 Jul 2019
British Journal of Cancer

Volume: 121, P: 429-430
Quality-adjusted survival with combination nal-IRI+5-FU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy: a Q-TWiST analysis

Uwe Pelzer
Jean-Frédéric Blanc
Richard A Hubner
ResearchOpen Access28 Mar 2017
British Journal of Cancer

Volume: 116, P: 1247-1253
A role for Id in the regulation of TGF-β-induced epithelial–mesenchymal transdifferentiation

M Kondo
E Cubillo
K Miyazono
Research04 Jun 2004
Cell Death & Differentiation

Volume: 11, P: 1092-1101
Reply: ‘Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer’

R Alvarez
M Musteanu
M Hidalgo
CorrespondenceOpen Access18 Mar 2014
British Journal of Cancer

Volume: 111, P: 1677-1678

Search

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin

Dissociable mechanisms govern when and how strongly reward attributes affect decisions

Determining factors and alternatives for the career development of women executives: a multicriteria decision model

Case–Control Genome-Wide Association Study of Persistent Attention-Deficit Hyperactivity Disorder Identifies FBXO33 as a Novel Susceptibility Gene for the Disorder

ADHD, Smoking Withdrawal, and Inhibitory Control: Results of a Neuroimaging Study with Methylphenidate Challenge

Stromal disrupting effects of nab-paclitaxel in pancreatic cancer

A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer

Erratum: Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism

Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism

Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis

Correction: A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer

Quality-adjusted survival with combination nal-IRI+5-FU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy: a Q-TWiST analysis

A role for Id in the regulation of TGF-β-induced epithelial–mesenchymal transdifferentiation

Reply: ‘Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer’

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