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Showing 1–50 of 58 results

Advanced filters: Author: Bei Shu Clear advanced filters

Correction: CLPTM1L interacts with ERLIN2 to stabilize SREBP1 and drive tumorigenesis in nasopharyngeal carcinoma

Jian Zhang
Shu-Qiang Liu
Chun-Ling Luo
Amendments and CorrectionsOpen Access26 Aug 2025
Cell Death & Disease

Volume: 16, P: 1
Photocatalyst-free photochemical deuteration via H/D exchange with D₂O

N–heterocyclic carbene copper complexes were explored as electrocatalysts for selectively reducing acetylene to ethylene, where electron–rich copper sites intrinsically facilitate acetylene adsorption and ethylene desorption, and thus achieved high activity and selectivity for ethylene production.

Ying Meng
Bei Shu
Wei Wang
ResearchOpen Access22 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Creating amphiphilic porosity in two-dimensional covalent organic frameworks via steric-hindrance-mediated precision hydrophilic-hydrophobic microphase separation

Creating different pore environments within a covalent organic framework (COF) leads to useful multicompartment structure and multiple functions. Here, the authors propose a strategy to construct amphiphilic COFs with separated hydrophilic and hydrophobic nanochannels by precisely controlling the distribution of hydrophilic and hydrophobic segments in two different kinds of pores.

Shu-Yan Jiang
Zhi-Bei Zhou
Xin Zhao
ResearchOpen Access24 Jan 2024
Nature Communications

Volume: 15, P: 1-7
Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment

Inflammatory immune cells are found in the synovial fluid of patients with rheumatoid arthritis (RA). Here the authors use scRNA sequencing of synovial fluid cells from RA patients before and after treatment with adalimumab/tofacitinib and find changes in inflammatory SPP1+ macrophages and explore the function of these cells in mouse models.

Xuyang Xia
Chenjia He
Qibing Xie
ResearchOpen Access04 Mar 2025
Nature Communications

Volume: 16, P: 1-23
SEAD reference panel with 22,134 haplotypes boosts rare variant imputation and genome-wide association analysis in Asian populations

Limited whole genome sequencing (WGS) of Asian populations results in a lack of representative reference panels, hindering imputation of Asian ancestry-specific genetic variants. Here the authors use WGS data from 11,067 individuals across 17 Asian countries to create a new reference panel which shows improved imputation accuracy for South Asian populations.

Meng-Yuan Yang
Jia-Dong Zhong
Hou-Feng Zheng
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-14
Granzyme K⁺CD8⁺ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps

Chronic rhinosinusitis with nasal polyps generally has a type 2 inflammatory eosinophilic profile but can have a treatment resistant neutrophilic phenotype. Here the authors characterise nasal polyps using single cell sequencing and spatial transcriptomics and show granzyme K⁺CD8⁺ T cells associated with neutrophilic inflammation which promote release of neutrophilic chemoattractants from fibroblasts.

Cui-Lian Guo
Chong-Shu Wang
Zheng Liu
ResearchOpen Access29 Nov 2024
Nature Communications

Volume: 15, P: 1-22
AI-enhanced virtual screening approach to hit identification for GluN1/GluN3A NMDA receptor

Yue-shan Ji
Yue Zeng
Yue Kong
Research26 Aug 2025
Acta Pharmacologica Sinica

P: 1-12
Association of HLA-DRA expression with prognosis and tumor microenvironment in clear cell renal cell carcinoma

Shu-Xin Qu
Xiang Wang
Rui Cui
ResearchOpen Access10 Aug 2025
Scientific Reports

Volume: 15, P: 1-16
Camrelizumab and apatinib plus induction chemotherapy and concurrent chemoradiotherapy in stage N3 nasopharyngeal carcinoma: a phase 2 clinical trial

The antiangiogenic agent apatinib has been shown to clinically improve responses to immune checkpoint inhibitors in several cancer types. Here the authors report the results of a phase II clinical trial of camrelizumab (anti-PD1) and apatinib plus induction chemotherapy and concurrent chemoradiotherapy in stage N3 nasopharyngeal carcinoma.

Hu Liang
Yao-Fei Jiang
Yan-Qun Xiang
ResearchOpen Access03 Feb 2024
Nature Communications

Volume: 15, P: 1-8
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis

Inhibition of immunocyte infiltration and activation has been suggested to ameliorate hepatic inflammation and fibrosis in nonalcoholic steatohepatitis. Here, the authors show PirB/LILRB2 regulates the migration of macrophages during NASH by binding with ANGPTL8, which is involved in the regulation of NASH development.

Dan-Pei Li
Li Huang
Xue-Feng Yu
ResearchOpen Access22 Jul 2023
Nature Communications

Volume: 14, P: 1-17
Research on the network structure evolution characteristics of outdoor sports tourism flow in the Yangtze River Economic belt based on online travel notes

Nianle Xiao
Binbin Zhao
ResearchOpen Access10 Jul 2025
Scientific Reports

Volume: 15, P: 1-18
Author Correction: Bilayer tungsten diselenide transistors with on-state currents exceeding 1.5 milliamperes per micrometre

Ruixia Wu
Quanyang Tao
Xiangfeng Duan
Amendments and Corrections14 Nov 2022
Nature Electronics

Volume: 5, P: 822
Trends in maternal and child health in China and its urban and rural areas from 1991 to 2020: a joinpoint regression model

Xin‒yue Wang
Bei‒bei Zhang
Jun‒hui Zhang
ResearchOpen Access12 Jun 2024
Scientific Reports

Volume: 14, P: 1-9
Genomic analyses of 10,376 individuals in the Westlake BioBank for Chinese (WBBC) pilot project

Biobanks of genetic data have been primarily in European populations, which gives us an incomplete understanding of complex traits across populations. Here, the authors initiate the Westlake BioBank for Chinese (WBBC) pilot project with 4,535 whole genome sequences and 5,841 high-density genotypes from China, characterizing large-scale genomic variation in Chinese populations.

Pei-Kuan Cong
Wei-Yang Bai
Hou-Feng Zheng
ResearchOpen Access26 May 2022
Nature Communications

Volume: 13, P: 1-15
AK4 promotes nasopharyngeal carcinoma metastasis and chemoresistance by activating NLRP3 inflammatory complex

Sai-Lan Liu
Li Yuan
Hai-Qiang Mai
ResearchOpen Access01 Jul 2025
Cell Death & Disease

Volume: 16, P: 1-13
New loci and coding variants confer risk for age-related macular degeneration in East Asians

Age-related macular degeneration (AMD) is a major cause of blindness worldwide. Here, the authors carry out a two-stage genome-wide association study for AMD and identify three new AMD risk loci, highlighting the shared and distinct genetic basis of the disease in East Asians and Europeans.

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
ResearchOpen Access28 Jan 2015
Nature Communications

Volume: 6, P: 1-10
Bilayer tungsten diselenide transistors with on-state currents exceeding 1.5 milliamperes per micrometre

Vanadium diselenide van der Waals contacts made with a controlled crack formation process can be used to fabricate tungsten diselenide transistors with channel lengths of less than 100 nm, on-state current densities of up to 1.7 mA μm^–1 and on-state resistances down to 0.50 kΩ μm.

Ruixia Wu
Quanyang Tao
Xiangfeng Duan
Research08 Aug 2022
Nature Electronics

Volume: 5, P: 497-504
Insight-HXMT observations of jet-like corona in a black hole X-ray binary MAXI J1820+070

Evolution of accretion disk and corona during outbursts in black hole binary systems is still unclear. Here, the authors show spectral analysis of MAXI J1820+070 and propose a scenario of a dynamical corona to explain the evolution of the reflection fraction observed by Insight-HXMT.

Bei You
Yuoli Tuo
Yue Zhu
ResearchOpen Access15 Feb 2021
Nature Communications

Volume: 12, P: 1-11
Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

Dongxin Lin, Philip Taylor, Li-Dong Wang and colleagues have now pooled three genome-wide association analyses of esophageal squamous cell carcinoma, finding two new risk loci at genome-wide significance and an HLA class II locus of significance in high-risk populations. They reanalyze the strength of evidence for previously published risk loci.

Chen Wu
Zhaoming Wang
Stephen J Chanock
Research01 Sept 2014
Nature Genetics

Volume: 46, P: 1001-1006
CLPTM1L interacts with ERLIN2 to stabilize SREBP1 and drive tumorigenesis in nasopharyngeal carcinoma

Jian Zhang
Shu-Qiang Liu
Chun-Ling Luo
ResearchOpen Access23 Jun 2025
Cell Death & Disease

Volume: 16, P: 1-10
Efficient strain modulation of 2D materials via polymer encapsulation

Strain engineering is a promising method to manipulate properties of two-dimensional (2D) materials but slippage between material and substrate makes strain transfer inefficient. Here the authors overcome slipping effects by encapsulating a 2D material in a polymer substrate.

Zhiwei Li
Yawei Lv
Yuan Liu
ResearchOpen Access02 Mar 2020
Nature Communications

Volume: 11, P: 1-8
First-line camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and chemotherapy for advanced gastric cancer (SPACE): a phase 1 study

Xiaofeng Chen
Hao Xu
Yongqian Shu
ResearchOpen Access25 Mar 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-8
Correction: Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians

Ching-Yu Cheng
Kenji Yamashiro
Chiea Chuen Khor
Amendments and Corrections30 Mar 2015
Nature Communications

Volume: 6, P: 1
miR-29b contributes to multiple types of muscle atrophy

Skeletal muscle atrophy can occur in response to stimuli such as inactivity, fasting, and ageing. Here the authors show that expression of microRNA-29b promotes muscle atrophy by targeting IGF-1 and PI3K, and that its inhibition attenuates atrophy induced by denervation and immobilization in mice.

Jin Li
Mun Chun Chan
Junjie Xiao
ResearchOpen Access25 May 2017
Nature Communications

Volume: 8, P: 1-15
The oncogene c-Jun impedes somatic cell reprogramming

Pei and colleagues report that the oncogene c-Jun acts as a somatic cell reprogramming barrier, and that its truncated dominant-negative form can substitute for Oct4 in reprogramming.

Jing Liu
Qingkai Han
Duanqing Pei
Research22 Jun 2015
Nature Cell Biology

Volume: 17, P: 856-867
Effects of UV for Cycloaliphatic Epoxy Resin via Thermokinetic Models, Novel Calorimetric Technology, and Thermogravimetric Analysis

Bin Laiwang
Shang-Hao Liu
Chi-Min Shu
ResearchOpen Access26 Oct 2018
Scientific Reports

Volume: 8, P: 1-11
miR-224-3p inhibits autophagy in cervical cancer cells by targeting FIP200

Wang Fang
Shan Shu
Sun Bei
ResearchOpen Access12 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
Effect of short-term room temperature storage on the microbial community in infant fecal samples

Yong Guo
Sheng-Hui Li
Xiu Qiu
ResearchOpen Access26 May 2016
Scientific Reports

Volume: 6, P: 1-7
Predicting Subtypes of Thymic Epithelial Tumors Using CT: New Perspective based on a Comprehensive Analysis of 216 Patients

Yu-Chuan Hu
Lang Wu
Guang-Bin Cui
ResearchOpen Access10 Nov 2014
Scientific Reports

Volume: 4, P: 1-7
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

Duanqing Pei and colleagues show that BMP signaling to histone H3 lysine 9 methylation is a barrier to reprogramming somatic cells into induced pluripotent cells (iPSCs) and that its removal promotes the formation of fully reprogrammed iPSCs from pre-iPSCs. pre-iPSCs exhibit pluripotent properties but do not activate the core pluripotent network.

Jiekai Chen
He Liu
Duanqing Pei
Research02 Dec 2012
Nature Genetics

Volume: 45, P: 34-42
Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence

A natural language processing system can support physicians in diagnostic assessments by extracting clinical information from electronic medical records to accurately predict diagnosis in pediatric patients.

Huiying Liang
Brian Y. Tsui
Huimin Xia
Research11 Feb 2019
Nature Medicine

Volume: 25, P: 433-438
Epstein-Barr virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation

Ya-Qing Zhou
Jia-Xin Jiang
Jin-Xin Bei
ResearchOpen Access10 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-16
Sulforaphane prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating SIRT1 and subsequently inhibiting ER stress

Yun-peng Li
Shu-lin Wang
Ai-hua Chen
Research18 Jan 2016
Acta Pharmacologica Sinica

Volume: 37, P: 344-353
Astragalus polysaccharides suppress ICAM-1 and VCAM-1 expression in TNF-α-treated human vascular endothelial cells by blocking NF-κB activation

Yu-ping Zhu
Tao Shen
Jian Li
Research03 Jun 2013
Acta Pharmacologica Sinica

Volume: 34, P: 1036-1042
Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses

Wan Peng
Gao-Fei Li
Jin-Xin Bei
Research17 Dec 2024
Oncogene

Volume: 44, P: 835-848
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability

Xiao-ling Zhang
Wei-hong Du
Xin-chun Jin
Research20 Jun 2024
Acta Pharmacologica Sinica

Volume: 45, P: 2241-2252
RAB17 promotes endometrial cancer progression by inhibiting TFRC-dependent ferroptosis

Xing Zhou
Miaomiao Nie
Hongbo Wang
ResearchOpen Access06 Sept 2024
Cell Death & Disease

Volume: 15, P: 1-15
Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophages

Yuxin Shu
Nanfei Yang
Pingping Shen
ResearchOpen Access02 Feb 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-3
High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s disease

Chaodong Wang
Hankui Liu
Piu Chan
ResearchOpen Access23 Jul 2024
npj Parkinson's Disease

Volume: 10, P: 1-14
UBE2O reduces the effectiveness of interferon-α via degradation of IFIT3 in hepatocellular carcinoma

Heng Li
Yao Liu
Lian-Xin Liu
ResearchOpen Access21 Dec 2023
Cell Death & Disease

Volume: 14, P: 1-13
ACE2-independent infection of T lymphocytes by SARS-CoV-2

Xu-Rui Shen
Rong Geng
Peng Zhou
ResearchOpen Access11 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-11
Composition of gut microbiota in infants in China and global comparison

Ya-Shu Kuang
Sheng-Hui Li
Xiu Qiu
ResearchOpen Access09 Nov 2016
Scientific Reports

Volume: 6, P: 1-10
ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1

Shuang Yan
Man Song
Ping-Kun Zhou
ResearchOpen Access22 Sept 2021
Cell Death Discovery

Volume: 7, P: 1-12
A modified apical resection model with high accuracy and reproducibility in neonatal mouse and rat hearts

Yihua Bei
Chen Chen
Junjie Xiao
ResearchOpen Access18 Feb 2023
npj Regenerative Medicine

Volume: 8, P: 1-13
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia

Cheng-Long Hu
Bing-Yi Chen
Lan Wang
ResearchOpen Access27 Oct 2022
Cell Research

Volume: 32, P: 1105-1123
Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma

Xi-Ya Li
Ji-Chuan Wu
Lan Wang
ResearchOpen Access09 Nov 2022
Leukemia

Volume: 37, P: 164-177
Antimicrobial activity and comparative metabolomic analysis of Priestia megaterium strains derived from potato and dendrobium

Jia-Meng Liu
Yan-Tian Liang
Feng-Zhong Wang
ResearchOpen Access31 Mar 2023
Scientific Reports

Volume: 13, P: 1-11
Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

Rou-Jun Peng
Bo-Wei Han
Jin-Xin Bei
ResearchOpen Access13 Dec 2018
Leukemia

Volume: 33, P: 1451-1462
Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury

Yan-qing Wu
Jun Xiong
Jian Xiao
Research03 Sept 2021
Acta Pharmacologica Sinica

Volume: 43, P: 1360-1371
setd2 knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals

Dian-Jia Liu
Fan Zhang
Xiao-Jian Sun
ResearchOpen Access20 Oct 2020
Cell Discovery

Volume: 6, P: 1-15

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