Epidemiological evidence has demonstrated associations between sleep and epilepsy, but we lack a mechanistic understanding of these associations. In this Review, Sheybani et al. consider the associations between epilepsy and sleep at the cellular, network and system levels, the mechanistic underpinnings of these associations and their clinical relevance to the management of epilepsy.
- Laurent Sheybani
- Birgit Frauscher
- Matthew C. Walker