Nature Search

Genome-resolved biogeography of Phaeocystales, cosmopolitan bloom-forming algae

Phaeocystales are ecologically significant nanoplankton whose evolutionary history and functional diversity remain incompletely characterized. Here, the authors integrate genomic and transcriptomic data to reveal their lineage diversification, metabolic plasticity, and adaptation to polar and temperate regimes.

Zoltán Füssy
Robert H. Lampe
Andrew E. Allen
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-18
Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial

Results from the randomized, noncomparative, phase 2 MATISSE trial show that ultra-short neoadjuvant therapy with ipilimumab and nivolumab can prevent surgery and radiotherapy in patients with resectable cutaneous squamous cell carcinoma, with an early decrease in total lesion glycolysis by [¹⁸F]FDG-PET/CT associated with response.

Sabine E. Breukers
Joleen J. H. Traets
Charlotte L. Zuur
ResearchOpen Access08 Oct 2025
Nature Medicine

P: 1-10
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations

Polygenic risk scores can help identify individuals at higher risk of type 2 diabetes. Here, the authors characterise a multi-ancestry score across nearly 900,000 people, showing that its predictive value depends on demographic and clinical context and extends to related traits and complications.

Boya Guo
Yanwei Cai
Burcu F. Darst
ResearchOpen Access01 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Dynamic observation of defect annealing in CdTe at lattice resolution

R. Sinclair
F. A. Ponce
C. J. D. Catto
Research08 Jul 1982
Nature

Volume: 298, P: 127-131
Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Genome-wide analyses identify 30 independent loci associated with obsessive–compulsive disorder, highlighting genetic overlap with other psychiatric disorders and implicating putative effector genes and cell types contributing to its etiology.

Nora I. Strom
Zachary F. Gerring
Manuel Mattheisen
ResearchOpen Access13 May 2025
Nature Genetics

Volume: 57, P: 1389-1401
Stratospheric trace gases in the spring 1986 Antarctic atmosphere

C. B. Farmer
G. C. Toon
L. L. Lowes
Research10 Sept 1987
Nature

Volume: 329, P: 126-130
Pangenome analysis reveals yield- and fiber-related diversity and interspecific gene flow in Gossypium barbadense L.

Comparing to Gossypium hirsutum, G. barbadense cotton lines have superior fiber quality but lower fiber yield. Here, the authors construct pangenome using 12 newly assembled G. barbadense genomes and 17 publicly tetraploid cotton genomes and reveal yield- and fiber-related diversity and interspecific gene flow.

Qingying Meng
Peihao Xie
Daojun Yuan
ResearchOpen Access29 May 2025
Nature Communications

Volume: 16, P: 1-18
Lipase Activity in the Slow- and Fast-contracting Leg Muscles of the Cockroach

J. C. GEORGE
N. M. G. BHAKTHAN
Research28 Oct 1961
Nature

Volume: 192, P: 356
Inhibition of the Aggregation of Blood Platelets by Nucleosides

SONIA CLAYTON
G. V. R. BORN
M. J. CROSS
Research12 Oct 1963
Nature

Volume: 200, P: 138-139
Estimation of Electron Affinities of Oxygen by Extrapolations of Ionization Potentials

D. F. C. MORRIS
H. N. SCHMEISING
Research15 Feb 1958
Nature

Volume: 181, P: 469-470
Determinants influencing the flow of FDI in India: an empirical insight using panel data

Rithi S. R
Abuzar Nomani
Manoharan M
ResearchOpen Access26 Sept 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-12
MOFs, holistically

Adsorption-based CO₂ capture is characterized by significant interdependencies between sorbent properties, CO₂ sources and process design. Research now underlines that a holistic approach is essential for designing high-performing materials and processes from techno-economic-environmental perspectives.

Matteo C. Romano
News & Views18 Sept 2024
Nature Energy

Volume: 9, P: 1054-1055
Amounts of Oxides of Nitrogen and Carbon Monoxide in Cigarette Smoke, with and without Inhalation

C. BOKHOVEN
H. J. NIESSEN
Research04 Nov 1961
Nature

Volume: 192, P: 458-459
Evidence for a K/T impact event in the Pacific Ocean

E. Robin
L. Froget
R. Rocchia
Research17 Jun 1993
Nature

Volume: 363, P: 615-617
Momentum-dependent scaling exponents of nodal self-energies measured in strange metal cuprates and modelled using semi-holography

Strange metal behaviour of high-Tc superconductors, characterised by unconventional electrical and thermodynamic properties, still poses challenges for theory. Smit et al. report experimental features in the self-energy of a strange metal that are consistent with predictions by holographic theoretical methods.

S. Smit
E. Mauri
M. S. Golden
ResearchOpen Access29 May 2024
Nature Communications

Volume: 15, P: 1-8
Intermediary Metabolism of Tryptophan

C. E. DALGLIESH
W. E. KNOX
A. NEUBERGER
Research07 Jul 1951
Nature

Volume: 168, P: 20-22
Sequence of the First 175 Nucleotides from the 5′ Terminus of Qβ RNA synthesized in vitro

M. A. BILLETER
J. E. DAHLBERG
C. WEISSMANN
Research13 Dec 1969
Nature

Volume: 224, P: 1083-1086
Terrestrial catastrophe caused by cometary impact at the end of Cretaceous

Kenneth J. Hsü
Research22 May 1980
Nature

Volume: 285, P: 201-203
Trace element patterns at a non-marine Cretaceous–Tertiary boundary

J. S. Gilmore
J. D. Knight
R. H. Tschudy
Research19 Jan 1984
Nature

Volume: 307, P: 224-228
Tight linkage between a splicing mutation and a specific DNA haplotype in phenylketonuria

Anthony G. DiLella
Joshua Marvit
Savio L. C. Woo
Research28 Aug 1986
Nature

Volume: 322, P: 799-803
Sublithospheric diamond ages and the supercontinent cycle

The ages and geochemical compositions of inclusions of sublithospheric diamonds indicate additions to the mantle keel of Gondwana by the underplating of buoyant subducted material, originating from 300–700-km depth, which may have contributed to supercontinent stability during long-distance migration.

Suzette Timmerman
Thomas Stachel
D. Graham Pearson
ResearchOpen Access18 Oct 2023
Nature

Volume: 623, P: 752-756
Effect of Inhibition of RNA Synthesis on Neural Information Storage

STANLEY H. APPEL
Research01 Sept 1965
Nature

Volume: 207, P: 1163-1166
Induced Optical Activity of 2,4-Dinitrophenyl-lysine Specifically Bound to Mouse MOPC-315 Myeloma Protein

JOHN M. ROCKEY
KEITH J. DORRINGTON
PAUL C. MONTGOMERY
Research16 Jul 1971
Nature

Volume: 232, P: 192-194
Polymorphism of the major envelope glycoprotein (gp70) of murine C-type viruses: virion associated and differentiation antigens encoded by a multi-gene family

J. H. Elder
F. C. Jensen
R. A. Lerner
Research05 May 1977
Nature

Volume: 267, P: 23-28
Genetic linkage of vitelliform macular degeneration (Best's disease) to chromosome 11q13

Edwin M. Stone
Brian E. Nichols
Val C. Sheffield
Research01 Jul 1992
Nature Genetics

Volume: 1, P: 246-250
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study

Tumor cells can evade immune detection by downregulating commonly recognized antigens, presenting a major challenge for effective immunotherapy. In this first-in-human study, the authors showed that the activation of T cells recognizing a new class of tumor antigens presented by immunotherapy-escaped tumor cells is safe and may lead to clinical benefit.

Mitchell Emmers
Marij J. P. Welters
Sjoerd H. van der Burg
ResearchOpen Access28 May 2025
Nature Communications

Volume: 16, P: 1-14
Upper Cretaceous to Eocene pelagic limestones of the Scaglia Rossa are not Miocene turbidites (reply)

F. C. Wezel
Research19 Nov 1981
Nature

Volume: 294, P: 248
Stimulation of Cell Locomotion and Pseudopod Formation by Heparin

L. G. E. BELL
K. W. JEON
Research28 Jul 1962
Nature

Volume: 195, P: 400-401
The South African Association for the Advancement of Science: diamond Jubilee Congress

A. C. BROWN
Research01 Sept 1962
Nature

Volume: 195, P: 845-847
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

A new study from the eMERGE consortium provides insights on the development of a pipeline for the generation and reporting of polygenic risk scores for ten diseases to diverse populations in a clinical setting.

Niall J. Lennon
Leah C. Kottyan
Eimear E. Kenny
ResearchOpen Access19 Feb 2024
Nature Medicine

Volume: 30, P: 480-487
Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes

Nam-Hoon Kim
Bong-Ki Hong
Wan-Uk Kim
ResearchOpen Access19 Jul 2013
Experimental & Molecular Medicine

Volume: 45, P: e32
Did komatiitic lavas erode channels on Mars?

ALEX K. BAIRD
BENTON C. CLARK
Research06 Sept 1984
Nature

Volume: 311, P: 18
Climate and the pollen record

P. C. Tzedakis
K. D. Bennett
D. Magri
Research18 Aug 1994
Nature

Volume: 370, P: 513
Expansion of satellite DNAs derived from transposable elements in beetles with reduced diploid numbers

José M. Rico-Porras
Pablo Mora
Diogo C. Cabral-de-Mello
Research24 Aug 2025
Heredity

Volume: 134, P: 529-541
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Analyses of genome and exome sequencing data identify rare coding and structural variants associated with atrial fibrillation and highlight genetic links between atrial fibrillation and cardiomyopathies.

Seung Hoan Choi
Sean J. Jurgens
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 548-562
Global fire at the Cretaceous– Tertiary boundary

Wendy S. Wolbach
Iain Gilmour
Robert R. Brooks
Research01 Aug 1988
Nature

Volume: 334, P: 665-669
Metallic behaviour in a Pt₃₀₉ cluster revealed by ¹⁹⁷Au Mössbauer spectroscopy

F. M. Mulder
T. A. Stegink
G. Schmid
Research24 Feb 1994
Nature

Volume: 367, P: 716-718
Data-driven design of metal–organic frameworks for wet flue gas CO₂ capture

Data mining of a computational library of metal–organic frameworks identifies motifs that bind CO₂ sufficiently strongly and whose uptake is not affected by water, with application for the capture of CO₂ from flue gases.

Peter G. Boyd
Arunraj Chidambaram
Berend Smit
Research11 Dec 2019
Nature

Volume: 576, P: 253-256
Glass from the Cretaceous/Tertiary boundary in Haiti

Haraldur Sigurdsson
Steven D'Hondt
James E. T. Channel
Research07 Feb 1991
Nature

Volume: 349, P: 482-487
Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer

Assessment of PD-1 and PD-L1 expression can be predictive of immunotherapy response in lung cancer. Here the authors assess the clinical toxicity, safety and quality of non-invasive imaging of PD-1 and PD-L1 expression in 13 patients with advanced lung cancer prior to treatment with immunotherapy and show it correlates with response.

A. N. Niemeijer
D. Leung
A. J. de Langen
ResearchOpen Access07 Nov 2018
Nature Communications

Volume: 9, P: 1-5
The sequence and analysis of duplication-rich human chromosome 16

Joel Martin
Cliff Han
Len A. Pennacchio
Research23 Dec 2004
Nature

Volume: 432, P: 988-994
Rotation in [C ii]-emitting gas in two galaxies at a redshift of 6.8

The emission of singly ionized carbon is used to identify two galaxies with redshifts of nearly 7—corresponding to the Universe’s first billion years—and with velocity structures suggestive of rotation.

Renske Smit
Rychard J. Bouwens
Wei Zheng
Research11 Jan 2018
Nature

Volume: 553, P: 178-181
The long non-coding RNA landscape of Candida yeast pathogens

Long non-coding RNAs (lncRNAs) play roles in key cellular processes, but remain largely unexplored in fungal pathogens such as Candida. Here, Hovhannisyan and Gabaldón analyze thousands of sequencing datasets to infer and characterize the lncRNA repertoires of five Candida species, paving the way for their future functional characterization.

Hrant Hovhannisyan
Toni Gabaldón
ResearchOpen Access16 Dec 2021
Nature Communications

Volume: 12, P: 1-13
Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery

The authors found, after analyzing 10,960 individuals from 9 multiancestry biobanks across 6 countries, that genetic factors previously associated with BMI have limited impact on GLP-1 receptor agonist-induced weight loss.

Jakob German
Mattia Cordioli
Andrea Ganna
ResearchOpen Access18 Apr 2025
Nature Medicine

Volume: 31, P: 2269-2276
Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain

RNA alternative splicing is involved in determining cell identity, but a comprehensive molecular map is missing. Here, the authors provide a human and mouse brain atlas of transcript isoforms linking them to cellular identity, brain regions and development stages.

Anoushka Joglekar
Wen Hu
Hagen U. Tilgner
ResearchOpen Access09 Apr 2024
Nature Neuroscience

Volume: 27, P: 1051-1063
Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells

How chromatin-associated RNAs (caRNAs) are spatially organized in the context of the multiscale genome architecture is unclear. Here the authors suggest how the 3D genome architecture can modulate the spatial distribution of caRNAs at different scales, and how in turn caRNA could affect the dynamic 3D genome organization.

Riccardo Calandrelli
Xingzhao Wen
Sheng Zhong
ResearchOpen Access16 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein

Reactivation of human cytomegalovirus in immunosuppressed transplant patients can cause severe complications. Here, Krishnaet al. show that a fusion toxin protein that specifically binds the viral surface protein US28 can be used to kill latently infected monocytes and their progenitor cells in vitro.

B. A. Krishna
K. Spiess
J. H. Sinclair
ResearchOpen Access02 Feb 2017
Nature Communications

Volume: 8, P: 1-9
Ostriches recognise their own eggs and discard others

BRIAN C. R. BERTRAM
Research17 May 1979
Nature

Volume: 279, P: 233-234
Initial sequencing and comparative analysis of the mouse genome

Asif T. Chinwalla
Lisa L. Cook
Michael C. Zody
Research05 Dec 2002
Nature

Volume: 420, P: 520-562

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