Nature Search

Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer

Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining neuroendocrine–tuft heterogeneity and offering new perspectives for targeting lineage plasticity.

Abbie S. Ireland
Daniel A. Xie
Trudy G. Oliver
ResearchOpen Access17 Sept 2025
Nature

P: 1-11
THE RELATIONS BETWEEN SCIENCE AND ETHICS

C. H. WADDINGTON
Research06 Sept 1941
Nature

Volume: 148, P: 270-274
Active Principle of the Amphibian Organisation Centre

C. H. WADDINGTON
J. NEEDHAM
R. LEMBERG
Research21 Jul 1934
Nature

Volume: 134, P: 103
Selection of the Genetic Basis for an Acquired Character

C. H. WADDINGTON
Research12 Apr 1952
Nature

Volume: 169, P: 625-626
Organizers in Mammalian Development

C. H. WADDINGTON
Research18 Jul 1936
Nature

Volume: 138, P: 125
Synthesis of Ribonucleic Acid by Different Regions of the Early Amphibian Embryo

C. H. WADDINGTON
E. PERKOWSKA
Research18 Sept 1965
Nature

Volume: 207, P: 1244-1246
Evolutionary Systems–Animal and Human

C. H. WADDINGTON
Research13 Jun 1959
Nature

Volume: 183, P: 1634-1638
THE RELATIONS BETWEEN SCIENCE AND ETHICS

C. E. M. JOAD
News06 Sept 1941
Nature

Volume: 148, P: 276-277
Canalization of Development and Genetic Assimilation of Acquired Characters

C. H. WADDINGTON
Research13 Jun 1959
Nature

Volume: 183, P: 1654-1655
Skin-resident innate lymphoid cells converge on a pathogenic effector state

In studies using mouse models of psoriasis, a spectrum of innate lymphoid cell types is reconfigured and converges via multiple trajectories on a type 3-like state, demonstrating the range and flexibility of innate lymphoid cell responses in the skin.

Piotr Bielecki
Samantha J. Riesenfeld
Richard A. Flavell
Research03 Feb 2021
Nature

Volume: 592, P: 128-132
Towards a Theoretical Biology

C. H. WADDINGTON
Research01 May 1968
Nature

Volume: 218, P: 525-527
True and False Teleology

C. H. WADDINGTON
Research04 May 1940
Nature

Volume: 145, P: 705
Evolution of Developmental Systems

C. H. WADDINGTON
Research25 Jan 1941
Nature

Volume: 147, P: 108-110
Some European Contributions to the Prehistory of Molecular Biology

C. H. WADDINGTON
Research25 Jan 1969
Nature

Volume: 221, P: 318-321
Structural variation in the pangenome of wild and domesticated barley

A pangenome analysis of 76 wild and domesticated barley accessions in combination with short-read sequence data of 1,315 barley genotypes indicates that allelic diversity at structurally complex loci may have helped crop plants to adapt to agricultural ecosystems.

Murukarthick Jayakodi
Qiongxian Lu
Nils Stein
ResearchOpen Access13 Nov 2024
Nature

Volume: 636, P: 654-662
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

Analysis of colorectal cancer bulk gene expression data at the pathway level identifies a poor-prognosis subtype associated with cell differentiation. The subtypes are reproducible in single-cell data and offer biological insights beyond existing stratification strategies.

Sudhir B. Malla
Ryan M. Byrne
Philip D. Dunne
ResearchOpen Access13 Feb 2024
Nature Genetics

Volume: 56, P: 458-472
Congenital Hyperglycæmia in Mice

HANS GRÜNEBERG
J. B. S. HALDANE
Research04 May 1940
Nature

Volume: 145, P: 704-705
Carbon Dioxide: A Factor Influencing Cell Division

C. L. MER
D. R. CAUSTON
Research27 Jul 1963
Nature

Volume: 199, P: 360-362
CLAVATA signalling shapes barley inflorescence by controlling activity and determinacy of shoot meristem and rachilla

Grasses have evolved a wide variety of inflorescence architectures. Here Vardanega et. al show how the barley CLV1 receptor and FCP1 peptide signal interact to control meristem shape, organ formation and determinacy thus shaping barley spike morphology.

Isaia Vardanega
Jan Eric Maika
Rüdiger Simon
ResearchOpen Access26 Apr 2025
Nature Communications

Volume: 16, P: 1-14
Molecular Biology or Ultrastructural Biology?

C. H. WADDINGTON
Research17 Jun 1961
Nature

Volume: 190, P: 1124-1125
Forecasting Weather from Solar Radiation

C. G. ABBOT
Research08 May 1954
Nature

Volume: 173, P: 880
Determination, Activation and Actinomycin D Insensitivity in the Optic Imaginal Disk of Drosophila

C. H. WADDINGTON
EVELYN ROBERTSON
Research08 Mar 1969
Nature

Volume: 221, P: 933-935
GABA mediated circling from substantia nigra

C. REAVILL
N. LEIGH
C. D. MARSDEN
Research01 Sept 1980
Nature

Volume: 287, P: 368
Recent Echo Sounder Studies

G. C. TROUT
A. J. LEE
F. R. HARDEN JONES
Research12 Jul 1952
Nature

Volume: 170, P: 71-72
The Concept of Polygenes

A. C. FABERGÉ
Research05 Jun 1943
Nature

Volume: 151, P: 643
Spontaneous Ignition of Gaseous Hydrogen Azide

PETER GRAY
T. C. WADDINGTON
Research16 Mar 1957
Nature

Volume: 179, P: 576-577
Electrical conductivity measurements from the GISP2 and GRIP Greenland ice cores

K. C. Taylor
C. U. Hammer
E. D. Waddington
Research09 Dec 1993
Nature

Volume: 366, P: 549-552
Evolution and Epistemology

C. H. WADDINGTON
Research08 May 1954
Nature

Volume: 173, P: 880
Physical Sciences: Solar Modulation and the Chemical Composition of the Cosmic Radiation

C. J. WADDINGTON
Research21 Apr 1972
Nature

Volume: 236, P: 391-392
CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS

C. H. WADDINGTON
Research14 Nov 1942
Nature

Volume: 150, P: 563-565
Lattice Energies, Charge Distributions and Thermochemical Data for Salts containing Complex Ions

H. D. B. JENKINS
T. C. WADDINGTON
Research05 Jul 1971
Nature Physical Science

Volume: 232, P: 5-7
Cancer and the Theory of Organisers

C. H. WADDINGTON
News20 Apr 1935
Nature

Volume: 135, P: 606-608
Operational Research

C. H. WADDINGTON
Research13 Mar 1948
Nature

Volume: 161, P: 404
Porphobilinogen: Chemical Constitution

G. H. COOKSON
C. RIMINGTON
Research16 May 1953
Nature

Volume: 171, P: 875-876
Imprinting and the Evolution of Instincts

J. B. S. HALDANE
HELEN SPURWAY
Research14 Jul 1956
Nature

Volume: 178, P: 85-86
Growth and Determination in the Development of Drosophila

C. H. WADDINGTON
Research07 Mar 1942
Nature

Volume: 149, P: 264-265
Correlation between Ulcerative Colitis and Rh Blood Groups

WILLIAM C. BOYD
MARY HEISLER
EGON OROWAN
Research17 Jun 1961
Nature

Volume: 190, P: 1123-1124
Sir Edward Sharpey-Schafer, F.R.S

J. A. C.
Comments & Opinion20 Apr 1935
Nature

Volume: 135, P: 608-610
Comparison of oxygen isotope records from the GISP2 and GRIP Greenland ice cores

P. M. Grootes
M. Stuiver
J. Jouzel
Research09 Dec 1993
Nature

Volume: 366, P: 552-554
Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks

Atefeh Taherian Fard
Sriganesh Srihari
Mark A Ragan
ResearchOpen Access18 Feb 2016
npj Systems Biology and Applications

Volume: 2, P: 1-9
Types of High Molecular Weight RNA in Embryos

C. H. WADDINGTON
Research18 Oct 1969
Nature

Volume: 224, P: 269-270
[Letter to Editors]

C. H. WADDINGTON
Research01 Nov 1941
Nature

Volume: 148, P: 534-535
Cryptorchism in Australian Merino Sheep

C. H. S. DOLLING
M. G. BROOKER
Research01 Jul 1964
Nature

Volume: 203, P: 49-50
Analysis of Environmental Variability in Quantitative Inheritance

E. C. R. REEVE
F. W. ROBERTSON
Research16 May 1953
Nature

Volume: 171, P: 874-875
Reflexions on Mind

J. C. ECCLES
Books & Arts20 Jul 1973
Nature

Volume: 244, P: 183-184
Nuclear Uptake of Glycine-2-¹⁴C in the Newt Embryo

J. L. SIRLIN
C. H. WADDINGTON
Research14 Aug 1954
Nature

Volume: 174, P: 309
Structure of Silver Iodide Dibenzoate

I. R. BEATTIE
D. BRYCE-SMITH
Research16 Mar 1957
Nature

Volume: 179, P: 577-578
Unbalanced response to growth variations reshapes the cell fate decision landscape

Zhu et al. show how the growth-rate-dependent gene expression reshapes the landscape of cell-fate determination and highlight that expression capacities of genes have unbalanced response to growth variations.

Jingwen Zhu
Pan Chu
Xiongfei Fu
Research23 Mar 2023
Nature Chemical Biology

Volume: 19, P: 1097-1104
Cosmic Ray Production by Vibrating Neutron Stars

A. G. W. CAMERON
Research26 Jun 1965
Nature

Volume: 206, P: 1342-1343
Single cell transcriptomics of human epidermis identifies basal stem cell transition states

The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial positioning of at least four basal stem cell populations.

Shuxiong Wang
Michael L. Drummond
Scott X. Atwood
ResearchOpen Access25 Aug 2020
Nature Communications

Volume: 11, P: 1-14

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