Specialized cell types in the medial entorhinal cortex (MEC), such as grid cells, are thought to provide spatial information to the hippocampus. Here the authors show that MEC lesions disrupt hippocampal theta phase precession, which suggests that the MEC is critical for cognitive functions that depend on precisely timed neuronal activity.
- Magdalene I Schlesiger
- Christopher C Cannova
- Stefan Leutgeb