Many patients who undergo doxorubicin chemotherapy develop cardiac complications later in life. Patient-derived cardiomyocytes can be used to predict individual susceptibility to drug-induced cardiotoxicity, as evidenced by enhanced doxorubicin responses in cardiomyocytes derived from induced pluripotent stem cells of patients who developed heart failure after chemotherapy.
- Milena Bellin
- Christine L. Mummery
