Nature Search

Incorporating social knowledge structures into computational models

People are remarkably good at learning about others’ personalities. Here, the authors develop computational models showing that this learning relies on a combination of prior beliefs and similarities between personality traits.

Koen M. M. Frolichs
Gabriela Rosenblau
Christoph W. Korn
ResearchOpen Access20 Oct 2022
Nature Communications

Volume: 13, P: 1-18
The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

Gabriele Grenningloh
Axel Rienitz
Heinrich Betz
Research16 Jul 1987
Nature

Volume: 328, P: 215-220
Giant magnetic splitting inducing near-unity valley polarization in van der Waals heterostructures

In transition metal dichalcogenide monolayers, the spin and valley degrees of freedom are strongly coupled. Here, the authors engineer a WSe₂/MoSe₂ heterostructure in which inter-valley transitions of interlayer excitons exhibit a giant splitting and near-unity polarization in a magnetic field.

Philipp Nagler
Mariana V. Ballottin
Tobias Korn
ResearchOpen Access16 Nov 2017
Nature Communications

Volume: 8, P: 1-6
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T_H17 cells

Korn and colleagues report that Sirpα⁺ dendritic cells trans-present the cytokine IL-6 to T cells through a process that requires its receptor IL-6Rα bound to dendritic cells and that trans-presentation is needed to generate pathogenic cells of the T_H17 subset of helper T cells in vivo.

Sylvia Heink
Nir Yogev
Thomas Korn
Research28 Nov 2016
Nature Immunology

Volume: 18, P: 74-85
Minimizing threat via heuristic and optimal policies recruits hippocampus and medial prefrontal cortex

Korn and Bach show that when humans have to trade off the opportunity to forage with the necessity of avoiding threat, they use a mix of optimal decision-making and heuristics. Hippocampal and medial prefrontal activity reflects these computations.

Christoph W. Korn
Dominik R. Bach
Research20 May 2019
Nature Human Behaviour

Volume: 3, P: 733-745
Loss avoidance during social interactions

This study disentangled loss avoidance from loss aversion, across seven experiments using social dilemmas with gains and losses. We found that people increased or decreased their cooperation to avoid losses. We found no consistent evidence for loss aversion.

Benjamin J. Kuper-Smith
Christoph W. Korn
ResearchOpen Access24 Jul 2025
Communications Psychology

Volume: 3, P: 1-10
How unrealistic optimism is maintained in the face of reality

This study reports that people are worse at incorporating negative information when updating their beliefs. Correspondingly, neural activity encodes desirable information updates, but there is weaker encoding of unexpectedly undesirable information.

Tali Sharot
Christoph W Korn
Raymond J Dolan
Research09 Oct 2011
Nature Neuroscience

Volume: 14, P: 1475-1479
Momentum-space indirect interlayer excitons in transition-metal dichalcogenide van der Waals heterostructures

A new type of exciton is observed in transition-metal dichalcogenide heterobilayers that is indirect in both real space and momentum space. It consists of a paired electron in MoS₂ at the K point and hole spread across MoS₂ and WSe₂ at the Γ point.

Jens Kunstmann
Fabian Mooshammer
Tobias Korn
Research30 Apr 2018
Nature Physics

Volume: 14, P: 801-805
Heuristic and optimal policy computations in the human brain during sequential decision-making

Alhough humans often make a series of related decisions, it is unknown whether this is done by relying on optimal or heuristic strategies. Here, the authors show that humans rely on both the best heuristic and the optimal policy, and that these strategies are controlled by parts of the medial prefrontal cortex.

Christoph W. Korn
Dominik R. Bach
ResearchOpen Access23 Jan 2018
Nature Communications

Volume: 9, P: 1-15
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development

Here the authors show that dihydroorotate dehydrogenase in the de novo pyrimidine synthesis pathway functions as a cell fate checkpoint that can be targeted to specifically diminish the number and function of effector T cells without affecting the memory T cell pool and response to infection.

Stefanie Scherer
Susanne G. Oberle
Dietmar Zehn
Research16 Feb 2023
Nature Immunology

Volume: 24, P: 501-515
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Factor XII initiates the intrinsic blood coagulation cascade and the kinin system. Here the authors show that Factor XII is elevated in the blood of multiple sclerosis patients, activates dendritic cells via CD87 and cAMP, and its blockade inhibits immunopathology in a mouse model of the disease.

Kerstin Göbel
Susann Pankratz
Sven G. Meuth
ResearchOpen Access18 May 2016
Nature Communications

Volume: 7, P: 1-16
Acceleration of inferred neural responses to oddball targets in an individual with bilateral amygdala lesion compared to healthy controls

Aslan Abivardi
Christoph W. Korn
Dominik R. Bach
ResearchOpen Access04 Sept 2023
Scientific Reports

Volume: 13, P: 1-13
Ly6D⁺Siglec-H⁺ precursors contribute to conventional dendritic cells via a Zbtb46⁺Ly6D⁺ intermediary stage

The ontogeny of conventional and plasmacytoid dendritic cells (DC) and how these two cell types are related is not fully known. Here the authors identify a pool of bone marrow precursor cells expressing Ly6D Siglec-H and Zbtb46 that can differentiate into either cDC or pDC and show that type I IFN can limit cDC and favor pDC output from these precursors.

Konstantin Lutz
Andrea Musumeci
Anne B. Krug
ResearchOpen Access16 Jun 2022
Nature Communications

Volume: 13, P: 1-15
Social preferences and psychopathy in a sample of male prisoners—a pilot study

Benjamin J. Kuper-Smith
Alexander Voulgaris
Christoph W. Korn
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-12
Coherent cyclotron motion beyond Kohn’s theorem

Kohn’s theorem states that the electron cyclotron resonance is unaffected by many-body interactions in a static magnetic field. Yet, intense terahertz pulses do introduce Coulomb effects between electrons—holding promise for quantum control of electrons.

T. Maag
A. Bayer
M. Kira
Research30 Nov 2015
Nature Physics

Volume: 12, P: 119-123
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies

Ralf Kittler
Vineeth Surendranath
Frank Buchholz
Research11 Mar 2007
Nature Methods

Volume: 4, P: 337-344
Population genomics and haplotype analysis in spelt and bread wheat identifies a gene regulating glume color

Krattinger, Abrouk et al. use genome wide association study and haplotype analyses to investigate the genetics of glume colour in ten reference grade wheat genomes. Haplotype comparison identifies a MYB transcription factor as a candidate gene for red glume colour.

Michael Abrouk
Naveenkumar Athiyannan
Simon G. Krattinger
ResearchOpen Access19 Mar 2021
Communications Biology

Volume: 4, P: 1-11
Gut CD4⁺ T cell phenotypes are a continuum molded by microbes, not by T_H archetypes

Helper T cell subsets are characterized functionally by the cytokines they produce. Benoist and colleagues demonstrate that in vivo helper T cells do not manifest as discrete helper subsets but rather form a continuum shaped by microbial exposure.

Evgeny Kiner
Elijah Willie
Hideyuki Yoshida
Research18 Jan 2021
Nature Immunology

Volume: 22, P: 216-228
Author Correction: Self-utility distance as a computational approach to understanding self-concept clarity

Josué García-Arch
Christoph W. Korn
Lluís Fuentemilla
Amendments and CorrectionsOpen Access11 Apr 2025
Communications Psychology

Volume: 3, P: 1
Self-utility distance as a computational approach to understanding self-concept clarity

This study introduces Self-Utility Distance, a mechanistically informed metric quantifying mismatches between self-concept traits and their perceived utility, and show it robustly predicts self-concept clarity across three empirical and computational studies.

Josué García-Arch
Christoph W. Korn
Lluís Fuentemilla
ResearchOpen Access25 Mar 2025
Communications Psychology

Volume: 3, P: 1-13
The ORFeome Collaboration: a genome-scale human ORF-clone resource

Stefan Wiemann
Christa Pennacchio
David E Hill
Correspondence25 Feb 2016
Nature Methods

Volume: 13, P: 191-192
Pupil diameter as an indicator of sound pair familiarity after statistically structured auditory sequence

Janika Becker
Christoph W. Korn
Helen Blank
ResearchOpen Access16 Apr 2024
Scientific Reports

Volume: 14, P: 1-14
Effect of valproate and pregabalin on human anxiety-like behaviour in a randomised controlled trial

Dominik R. Bach
Christoph W. Korn
Antonia Bantel
ResearchOpen Access16 Aug 2018
Translational Psychiatry

Volume: 8, P: 1-10

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