Individuals with acute ischemic stroke are frequently shown to have hyperglycemia when admitted to hospital and elevated levels of blood glucose are associated with a poor prognosis. Tight glycemic control (TGC) might be an effective treatment for hyperglycemia in patients with acute ischemic stroke; however, successful and safe provision of TGC is a challenging task. This Review examines the evidence linking hyperglycemia to unfavorable prognoses in patients with acute stroke, provides a systematic review of the literature concerning TGC treatment after stroke and proposes directions on how to treat hyperglycemia in patients with stroke.
- Nyika D. Kruyt
- Geert Jan Biessels
- Yvo B. Roos
