Cavernous malformations (CMs) are vascular malformations that mainly occur in the brain. Many patients with such lesions are asymptomatic; however, individuals with CMs can present with seizures, focal neurological deficits or intracranial hemorrhage. In this Review, Batra and colleagues examine the pathology, natural history and imaging of CMs. Furthermore, the authors discuss the use of pharmacology, surgical resection and stereotactic radiosurgery in the management of such lesions.
- Sachin Batra
- Doris Lin
- Daniele Rigamonti