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Showing 251–300 of 345 results

Advanced filters: Author: D Schaeffer Clear advanced filters

Resource utilization patterns using non-invasive ventilation in neonates with respiratory distress syndrome

Thomas A. Chavez
Ashwini Lakshmanan
Rangasamy Ramanathan
Research24 May 2018
Journal of Perinatology

Volume: 38, P: 850-856
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

RNA-Seq enables rapid sequencing of total cellular RNA and should allow the reconstruction of spliced transcripts in a cell population. Trapnell et al. achieve this and transcript quantification using only paired-end RNA-Seq data and an unannotated genome sequence, and apply the approach to characterize isoform switching over a developmental time course.

Cole Trapnell
Brian A Williams
Lior Pachter
Research02 May 2010
Nature Biotechnology

Volume: 28, P: 511-515
Phase II and pharmacokinetic study of paclitaxel therapy for unresectable hepatocellular carcinoma patients

Y Chao
W-K Chan
S-D Lee
Research01 Jul 1998
British Journal of Cancer

Volume: 78, P: 34-39
Scaffold proteins of MAP-kinase modules

D N Dhanasekaran
K Kashef
E P Reddy
Reviews14 May 2007
Oncogene

Volume: 26, P: 3185-3202
S-allele sequence diversity in natural populations of Solanum carolinense (Horsenettle)

Adam D Richman
Teh-Hui Kao
Marcy K Uyenoyama
Research01 Oct 1995
Heredity

Volume: 75, P: 405-415
Deep continental roots and cratons

Cratons are the oldest parts of the Earth’s continents; this Review concludes that the production of widespread, thick and strong lithosphere via the process of orogenic thickening was fundamental to the eventual emergence of extensive continental landmasses.

D. Graham Pearson
James M. Scott
Peter B. Kelemen
Reviews11 Aug 2021
Nature

Volume: 596, P: 199-210
Summation model of pelvic pain in interstitial cystitis

Many patients with interstitial cystitis (IC) note that particular foods can exacerbate their symptoms. In this Review, Klumpp and Rudick propose a model, based on pelvic-organ crosstalk, for this association between pain symptoms from IC and dietary modification.

David J Klumpp
Charles N Rudick
Reviews01 Sept 2008
Nature Clinical Practice Urology

Volume: 5, P: 494-500
RET ligand-induced internalization and its consequences for downstream signaling

D S Richardson
A Z Lai
L M Mulligan
Research16 Jan 2006
Oncogene

Volume: 25, P: 3206-3211
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines

Hillary Elrick
Kevin A. Peterson
Lauryl M. J. Nutter
ResearchOpen Access30 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
A resource of targeted mutant mouse lines for 5,061 genes

The International Mouse Phenotyping Consortium reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter alleles.

Marie-Christine Birling
Atsushi Yoshiki
Stephen A. Murray
Comments & Opinion08 Apr 2021
Nature Genetics

Volume: 53, P: 416-419
Cloning of a novel phosphotyrosine binding domain containing molecule, Odin, involved in signaling by receptor tyrosine kinases

Akhilesh Pandey
Blagoy Blagoev
Matthias Mann
Research13 Nov 2002
Oncogene

Volume: 21, P: 8029-8036
S-allele diversity in a natural population of Physalis crassifolia (Solanaceae) (ground cherry) assessed by RT-PCR

Adam D Richman
Marcy K Uyenoyama
Joshua R Kohn
Research01 May 1996
Heredity

Volume: 76, P: 497-505
Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects

Susanne Gaul
Karen Marie Schaeffer
Ulrich Laufs
ResearchOpen Access26 Jul 2021
Scientific Reports

Volume: 11, P: 1-13
The failure rate of NHS funded molar endodontic treatment delivered in general dental practice

M. Tickle
K. Milsom
V. R. Aggarwal
Research15 Feb 2008
British Dental Journal

Volume: 204, P: E8
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

Erica S. Tsang
Veronika Csizmok
Daniel J. Renouf
ResearchOpen Access24 Mar 2023
npj Precision Oncology

Volume: 7, P: 1-12
Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms

Julia Bauer
Nicole Cuvelier
Heidi Hahn
ResearchOpen Access25 Jun 2021
Oncogene

Volume: 40, P: 4955-4966
Persistent growth of CO₂ emissions and implications for reaching climate targets

In order to limit climate warming, CO₂ emissions must remain below fixed quota. An evaluation of past emissions suggests that at 2014 emissions rates, the total quota will probably be exhausted within the next 30 years.

P. Friedlingstein
R. M. Andrew
C. Le Quéré
Reviews21 Sept 2014
Nature Geoscience

Volume: 7, P: 709-715
Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials

Andre Esteva
Jean Feng
Osama Mohamad
ResearchOpen Access08 Jun 2022
npj Digital Medicine

Volume: 5, P: 1-8
Mapping the climate change challenge

A long-term goal for climate policy can only be agreed through political processes, but science can inform these through mapping policy choices and the risks they create. Recommendations for the practical use of the IPCC's Fifth Assessment Report are provided.

Stephane Hallegatte
Joeri Rogelj
Detlef P. van Vuuren
Reviews23 Jun 2016
Nature Climate Change

Volume: 6, P: 663-668
Effectiveness of ecological rescue for altered soil microbial communities and functions

Kadiya Calderón
Aymé Spor
Laurent Philippot
Research24 Jun 2016
The ISME Journal

Volume: 11, P: 272-283
Systematic differences in the response of genetic variation to pedigree and genome-based selection methods

M Heidaritabar
A Vereijken
J W M Bastiaansen
Research30 Jul 2014
Heredity

Volume: 113, P: 503-513
Paternal cocaine taking elicits epigenetic remodeling and memory deficits in male progeny

M E Wimmer
L A Briand
R C Pierce
Research21 Feb 2017
Molecular Psychiatry

Volume: 22, P: 1641-1650
Optimizing detection of clinically significant prostate cancer through nomograms incorporating mri, clinical features, and advanced serum biomarkers in biopsy naïve men

Mohammad R. Siddiqui
Eric V. Li
Ashley E. Ross
Research27 Mar 2023
Prostate Cancer and Prostatic Diseases

Volume: 26, P: 588-595
A molecular perspective on a complex polymorphic inversion system with cytological evidence of multiply reused breakpoints

D J Orengo
E Puerma
M Aguadé
Research25 Feb 2015
Heredity

Volume: 114, P: 610-618
Unregulated large language models produce medical device-like output

Gary E. Weissman
Toni Mankowitz
Genevieve P. Kanter
ResearchOpen Access07 Mar 2025
npj Digital Medicine

Volume: 8, P: 1-5
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences

Walter Rayford, Alp Tuna Beksac et al. investigated gene expression alterations in African-American and European-American men who underwent radical prostatectomy for prostate cancer. The observed differences include higher expression of inflammation genes and lower expression of mismatch repair genes in African-American men.

Walter Rayford
Alp Tuna Beksac
Ashutosh K. Tewari
ResearchOpen Access03 Jun 2021
Communications Biology

Volume: 4, P: 1-9
Regeneration of Fertile Plants from Protoplasts of Elite Inbread Maize.

Raymond D. Shillito
Gleta K. Carswell
Christian T. Harms
Research01 Jun 1989
Bio/Technology

Volume: 7, P: 581-587
The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer

Yi-Jye Chern
John C. T. Wong
Isabella T. Tai
ResearchOpen Access26 Jun 2019
Cell Death & Disease

Volume: 10, P: 1-14
Efficacy and safety of Stealth liposomal doxorubicin in AIDS-related Kaposi's sarcoma

F-D Goebel
D Goldstein
JS Stewart
Research01 Apr 1996
British Journal of Cancer

Volume: 73, P: 989-994
Association between maternal serious mental illness and adverse birth outcomes

H. Heun-Johnson
S. A. Seabury
A. Lakshmanan
Research08 Mar 2019
Journal of Perinatology

Volume: 39, P: 737-745
Genetic characterization of non-5q proximal spinal muscular atrophy in a French cohort: the place of whole exome sequencing

Julian Theuriet
Gorka Fernandez-Eulate
Antoine Pegat
ResearchOpen Access19 Jun 2023
European Journal of Human Genetics

Volume: 32, P: 37-43
Increased expression of nestin in the major pelvic ganglion following cavernous nerve injury

O Kutlu
A E Ross
T J Bivalacqua
Research13 Oct 2011
International Journal of Impotence Research

Volume: 24, P: 84-90
A genomic classifier predicting metastatic disease progression in men with biochemical recurrence after prostatectomy

A E Ross
F Y Feng
E M Schaeffer
Research22 Oct 2013
Prostate Cancer and Prostatic Diseases

Volume: 17, P: 64-69
In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components

Christine Woischke
Christian W Schaaf
David Horst
Research02 Sept 2016
Modern Pathology

Volume: 30, P: 95-103
The impact of COVID-19 vaccination rate on traffic recovery

Suyanpeng Zhang
Jing Jin
Sze-chuan Suen
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
SSR180711, a Novel Selective α7 Nicotinic Receptor Partial Agonist: (1) Binding and Functional Profile

Bruno Biton
Olivier E Bergis
Bernard Scatton
Research04 Oct 2006
Neuropsychopharmacology

Volume: 32, P: 1-16
Novel Analgesic Triglycerides from Cultures of Agaricus macrosporus and Other Basidiomycetes as Selective Inhibitors of Neurolysin

Marc Stadler
Veronika Hellwig
Nils Burkhardt
Research01 Dec 2005
The Journal of Antibiotics

Volume: 58, P: 775-786
Mismatch repair status may predict response to adjuvant chemotherapy in resectable pancreatic ductal adenocarcinoma

Maziar Riazy
Steve E Kalloger
David F Schaeffer
Research31 Jul 2015
Modern Pathology

Volume: 28, P: 1383-1389
A prostate derived commensal Staphylococcus epidermidis strain prevents and ameliorates induction of chronic prostatitis by UPEC infection

Stephen F. Murphy
Christel Hall
Praveen Thumbikat
ResearchOpen Access27 Nov 2018
Scientific Reports

Volume: 8, P: 1-10
Division of labour and terminal differentiation in a novel Bacillus thuringiensis strain

Chao Deng
Leyla Slamti
Fuping Song
Research01 Aug 2014
The ISME Journal

Volume: 9, P: 286-296
Rotating edge-field driven processing of chiral spin textures in racetrack devices

Alexander F. Schäffer
Pia Siegl
Elena Y. Vedmedenko
ResearchOpen Access23 Nov 2020
Scientific Reports

Volume: 10, P: 1-8
Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling

D J Hines
L I Schmitt
P G Haydon
ResearchOpen Access15 Jan 2013
Translational Psychiatry

Volume: 3, P: e212
Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders

L Yan
A Shamir
A Buonanno
ResearchOpen Access21 Mar 2017
Molecular Psychiatry

Volume: 23, P: 1233-1243
A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts

G Pratesi
P Perego
F Zunino
ResearchOpen Access30 Jul 1999
British Journal of Cancer

Volume: 80, P: 1912-1919
Stool-based biomarkers of interstitial cystitis/bladder pain syndrome

A. Braundmeier-Fleming
Nathan T. Russell
David J. Klumpp
ResearchOpen Access18 May 2016
Scientific Reports

Volume: 6, P: 1-10
The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases

This 96-well-plate ‘real-time quaking-induced conversion’ assay allows the detection of abnormal prion protein in human brain and CSF samples. It can be applied to study many protein misfolding diseases, as well as for drug screening and prion strain discrimination.

Matthias Schmitz
Maria Cramm
Inga Zerr
Protocols13 Oct 2016
Nature Protocols

Volume: 11, P: 2233-2242
Efficacy of post-operative radiation in a prostatectomy cohort adjusted for clinical and genomic risk

A E Ross
R B Den
E M Schaeffer
ResearchOpen Access03 May 2016
Prostate Cancer and Prostatic Diseases

Volume: 19, P: 277-282
American Life in Realtime: a benchmark registry of health data for equitable precision health

Ritika R. Chaturvedi
Marco Angrisani
Arie Kapteyn
Correspondence03 Feb 2023
Nature Medicine

Volume: 29, P: 283-286
Chromosomal alterations in the clonal evolution to the metastatic stage of squamous cell carcinomas of the lung

S Petersen
M Aninat-Meyer
I Petersen
ResearchOpen Access10 Dec 1999
British Journal of Cancer

Volume: 82, P: 65-73
Robert Lindsay, August 1926, and the American experience - Part 2: the seventh International Dental Congress

Helen Nield
Research28 Jul 2023
British Dental Journal

Volume: 235, P: 133-142

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