Nature Search

Elevated nonhomologous end-joining by AATF enables efficient DNA damage repair and therapeutic resistance in glioblastoma

Glioma stem-like cells (GSCs) contribute to therapeutic resistance via enhanced capability of DNA damage repair. Here the authors identify that the upregulated transcription factor AATF in GSCs modulates the stability and release of XRCC4 protein to promote DNA repair and resistance to radiotherapy.

Lanjuan Mi
Yan Cai
Jianghong Man
ResearchOpen Access28 May 2025
Nature Communications

Volume: 16, P: 1-19
Predicting factors associated with anxiety by patients undergoing treatment for infectious diseases using a random-forest machine learning approach

Ruijie Chang
Chenrui Li
Tian Shen
ResearchOpen Access01 Sept 2025
Scientific Reports

Volume: 15, P: 1-11
Grave-to-cradle upcycling of Ni from electroplating wastewater to photothermal CO₂ catalysis

The valorization of undesirable substrates offers a two-fold strategy for pollution remediation and renewable energy conversion. Here, authors demonstrate the scavenging of Ni from electroplating wastewater and subsequent utilization as materials for photothermal CO₂ reduction.

Shenghua Wang
Dake Zhang
Geoffrey A. Ozin
ResearchOpen Access09 Sept 2022
Nature Communications

Volume: 13, P: 1-11
Atlantic origin of the increasing Asian westerly jet interannual variability

The summer jet stream above East Asia has become more variable in recent decades, leading to weather and climate extremes across Eurasia. The authors show that a Scandinavian Pattern in preceding February is driving the strong variability.

Lifei Lin
Chundi Hu
Dake Chen
ResearchOpen Access09 Mar 2024
Nature Communications

Volume: 15, P: 1-10
Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance

How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for radiotherapy resistance in glioma stem-like cells.

Haohao Huang
Songyang Zhang
Jianghong Man
ResearchOpen Access17 Jun 2021
Nature Communications

Volume: 12, P: 1-16
Emergence of climate change in the tropical Pacific

Determining the emergent climate change signals in the tropical Pacific—mean state and El Niño/Southern Oscillation (ENSO)—is crucial for climate action. Model simulations show that the mean sea surface temperature signal is already detectable, and that mean rainfall and ENSO-related signals could emerge around 2040.

Jun Ying
Matthew Collins
Karl Stein
Research07 Mar 2022
Nature Climate Change

Volume: 12, P: 356-364
Ecological geological vulnerability assessment in Northern Shanxi Province (China) based on sensitivity resilience pressure (SRP) model

Yanlong Cai
Xiaoyu Guo
Jilin Zheng
ResearchOpen Access08 Mar 2025
Scientific Reports

Volume: 15, P: 1-19
Integrated algorithm combining plasma biomarkers and cognitive assessments accurately predicts brain β-amyloid pathology

Pan, Huang, Cai et al. develop computational models to predict brain β-amyloid (Aβ) pathology from plasma biomarkers, cognitive test scores and key demographics. The models accurately predict brain Aβ positivity enabling assessment of Aβ pathology in a non-invasive and cost-effective way.

Fengfeng Pan
Yanlu Huang
Qihao Guo
ResearchOpen Access10 May 2023
Communications Medicine

Volume: 3, P: 1-11
Anti-liver tumor ingredient exploration and validation of Elephantopus tomentosus Linn. by combining in silico and in vitro experiments

Zhihao Zeng
Canchao Jia
Xiaoli Bi
ResearchOpen Access10 Sept 2024
Scientific Reports

Volume: 14, P: 1-14
Tropical teleconnection impacts on Antarctic climate changes

Tropical teleconnections can influence polar climates through the generation of stationary Rossby waves. This Review outlines the dynamics and impacts of long-term tropical–polar connections on the Antarctic climate, which include warming trends and ice mass loss in West Antarctica.

Xichen Li
Wenju Cai
Chentao Song
Reviews31 Aug 2021
Nature Reviews Earth & Environment

Volume: 2, P: 680-698
Integrated network pharmacology and metabolomics reveal the mechanisms of Jasminum elongatum in anti-ulcerative colitis

Jinyan Qiu
Guanlin Xiao
Aili Xu
ResearchOpen Access17 Dec 2023
Scientific Reports

Volume: 13, P: 1-18

Search

Elevated nonhomologous end-joining by AATF enables efficient DNA damage repair and therapeutic resistance in glioblastoma

Predicting factors associated with anxiety by patients undergoing treatment for infectious diseases using a random-forest machine learning approach

Grave-to-cradle upcycling of Ni from electroplating wastewater to photothermal CO₂ catalysis

Atlantic origin of the increasing Asian westerly jet interannual variability

Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance

Emergence of climate change in the tropical Pacific

Ecological geological vulnerability assessment in Northern Shanxi Province (China) based on sensitivity resilience pressure (SRP) model

Integrated algorithm combining plasma biomarkers and cognitive assessments accurately predicts brain β-amyloid pathology

Anti-liver tumor ingredient exploration and validation of Elephantopus tomentosus Linn. by combining in silico and in vitro experiments

Tropical teleconnection impacts on Antarctic climate changes

Integrated network pharmacology and metabolomics reveal the mechanisms of Jasminum elongatum in anti-ulcerative colitis

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