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Showing 51–78 of 78 results

Advanced filters: Author: Eli Adams Clear advanced filters

New models of collaboration in genome-wide association studies: the Genetic Association Information Network

The Genetic Association Information Network (GAIN) is a public-private partnership established to investigate the genetic basis of common diseases through a series of collaborative genome-wide association studies. GAIN has used new approaches for project selection, data deposition and distribution, collaborative analysis, publication and protection from premature intellectual property claims. These demonstrate a new commitment to shared scientific knowledge that should facilitate rapid advances in understanding the genetics of complex diseases.

Teri A Manolio
Laura Lyman Rodriguez
Francis S Collins
Comments & Opinion29 Aug 2007
Nature Genetics

Volume: 39, P: 1045-1051
A dynamic map for learning, communicating, navigating and improving therapeutic development

John Wagner
Andrew M. Dahlem
Christopher P. Austin
Correspondence22 Dec 2017
Nature Reviews Drug Discovery

Volume: 17, P: 150
Author Correction: Universal DNA methylation age across mammalian tissues

A. T. Lu
Z. Fei
S. Horvath
Amendments and CorrectionsOpen Access06 Sept 2023
Nature Aging

Volume: 3, P: 1462
Recombinant Human Insulin-Like Growth Factor II Expressed in Escherichia coli

Thomas C. Furman
Janet Epp
Michele C. Smith
Research01 Oct 1987
Bio/Technology

Volume: 5, P: 1047-1051
Purification and direct transformation of epithelial progenitor cells from primary human prostate

Andrew S Goldstein
Justin M Drake
Owen N Witte
Protocols21 Apr 2011
Nature Protocols

Volume: 6, P: 656-667
Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

John Luk and colleagues report the sequencing of 81 hepatitis B virus (HBV)-positive and 7 HBV-negative hepatocellular carcinomas and matched normal tissues. They confirm recurrent integration events of HBV at TERT and MLL4 and report recurrent events at the CCNE1 gene.

Wing-Kin Sung
Hancheng Zheng
John M Luk
Research27 May 2012
Nature Genetics

Volume: 44, P: 765-769
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

A cell-free DNA-methylation sequencing assay accurately identifies renal cell carcinoma using plasma and urine samples.

Pier Vitale Nuzzo
Jacob E. Berchuck
Matthew L. Freedman
Research22 Jun 2020
Nature Medicine

Volume: 26, P: 1041-1043
Bax cleavage is mediated by calpain during drug-induced apoptosis

David E Wood
Anju Thomas
Elizabeth W Newcomb
Research04 Sept 1998
Oncogene

Volume: 17, P: 1069-1078
Group II Metabotropic Glutamate Receptor Modulation of DOI-induced c-fos mRNA and Excitatory Responses in the Cerebral Cortex

Yan Zhai
Carolyn A George
Laura K Nisenbaum
Research16 Dec 2003
Neuropsychopharmacology

Volume: 28, P: 45-52
Author Correction: Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures

A. E. Hussein
N. Senabulya
A. G. R. Thomas
Amendments and CorrectionsOpen Access10 Jan 2020
Scientific Reports

Volume: 10, P: 1
Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures

A. E. Hussein
N. Senabulya
A. G. R. Thomas
ResearchOpen Access01 Mar 2019
Scientific Reports

Volume: 9, P: 1-13
Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer

A mutation in RAS oncogene family-like 3 (RABL3) is discovered in a family with multiple cases of pancreatic cancer. Zebrafish modeling and biochemical approaches suggest that truncated RABL3 elevates KRAS activity via accelerated prenylation.

Sahar Nissim
Ignaty Leshchiner
Wolfram Goessling
Research12 Aug 2019
Nature Genetics

Volume: 51, P: 1308-1314
GigaGauss solenoidal magnetic field inside bubbles excited in under-dense plasma

Zs. Lécz
I. V. Konoplev
A. Andreev
ResearchOpen Access31 Oct 2016
Scientific Reports

Volume: 6, P: 1-11
Adipose tissue contribution to plasma fibroblast growth factor 21 and fibroblast activation protein in obesity

Marleen A. van Baak
Roel G. Vink
Edwin C. M. Mariman
ResearchOpen Access27 Aug 2019
International Journal of Obesity

Volume: 44, P: 544-547
ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

Rare variant association data from human genetics combined with in vitro and in vivo functional validation highlight ANGPTL7 as a promising therapeutic target for intraocular pressure reduction, and protection from glaucoma.

Kavita Praveen
Gaurang C. Patel
Giovanni Coppola
ResearchOpen Access03 Oct 2022
Communications Biology

Volume: 5, P: 1-15
The trend of disruption in the functional brain network topology of Alzheimer’s disease

Alireza Fathian
Yousef Jamali
Ansgar J. Furst
ResearchOpen Access02 Sept 2022
Scientific Reports

Volume: 12, P: 1-17
Population-scale analysis of common and rare genetic variation associated with hearing loss in adults

A GWAS and exome-wide association study meta-analysis identifies 53 loci affecting hearing loss risk from over half a million individuals across five cohorts. Rare variants in Mendelian hearing loss genes contribute to hearing loss risk in adults.

Kavita Praveen
Lee Dobbyn
Giovanni Coppola
ResearchOpen Access03 Jun 2022
Communications Biology

Volume: 5, P: 1-12
Wireless, non-invasive, wearable device for continuous remote monitoring of hemodynamic parameters in a swine model of controlled hemorrhagic shock

Dean Nachman
Keren Constantini
Yftach Gepner
ResearchOpen Access19 Oct 2020
Scientific Reports

Volume: 10, P: 1-10
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Simone de Jong et al. examine the balance of common and rare risk for psychiatric disorders in a large family with high incidence of Bipolar Disorder and Major Depressive Disorder. They find that increased polygenic risk over generations could be partially due to assortative mating, which may explain the observation of anticipation in mood disorders.

Simone de Jong
Mateus Jose Abdalla Diniz
Gerome Breen
ResearchOpen Access08 Oct 2018
Communications Biology

Volume: 1, P: 1-10
Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

R S Muraoka-Cook
I Shin
C L Arteaga
Research26 Sept 2005
Oncogene

Volume: 25, P: 3408-3423
E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

Shirley Polager
Yael Kalma
Doron Ginsberg
Research24 Jan 2002
Oncogene

Volume: 21, P: 437-446
Metabolic adaptation and maladaptation in adipose tissue

Adipose tissue responds to a variety of hormonal and environmental cues with changes in size, cellular composition and metabolic activity. Here Kajimura and Chouchani review our current understanding of adipocyte metabolism in physiology and metabolic disease, and they discuss strategies to reprogram adipocyte fate and metabolism.

Edward T. Chouchani
Shingo Kajimura
Reviews21 Jan 2019
Nature Metabolism

Volume: 1, P: 189-200
Defining suicidality phenotypes for genetic studies: perspectives of the Psychiatric Genomics Consortium Suicide Working Group

Sarah M. C. Colbert
Eric T. Monson
Lea Zillich
ReviewsOpen Access25 Sept 2025
Molecular Psychiatry

Volume: 30, P: 6144-6154
A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

Suprateek Kundu
Joshua Lukemire
Ansgar J. Furst
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-18
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Till F. M. Andlauer
Jose Guzman-Parra
Marcella Rietschel
ResearchOpen Access11 Nov 2019
Molecular Psychiatry

Volume: 26, P: 1286-1298
Common variant at 16p11.2 conferring risk of psychosis

S Steinberg
S de Jong
K Stefansson
Research20 Nov 2012
Molecular Psychiatry

Volume: 19, P: 108-114
Developing a Neuronal Model for the Pathophysiology of Schizophrenia Based on the Nature of Electrophysiological Actions of Dopamine in the Prefrontal Cortex

Charles R Yang
Jeremy K Seamans
Natalia Gorelova
Reviews01 Aug 1999
Neuropsychopharmacology

Volume: 21, P: 161-194
Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients

J Frank
M Lang
M Rietschel
CorrespondenceOpen Access03 Jun 2014
Molecular Psychiatry

Volume: 20, P: 150-151

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