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Showing 1–50 of 285 results

Advanced filters: Author: F Mena Clear advanced filters

Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression

Cells transmit mechanical force to the nucleus via the cytoskeleton. Here, the authors reveal a role for the actin regulator Mena in force transmission at the nuclear envelope, where it regulates nuclear architecture, chromatin organization and gene expression.

Frederic Li Mow Chee
Bruno Beernaert
Adam Byron
ResearchOpen Access23 Mar 2023
Nature Communications

Volume: 14, P: 1-19
Measuring disaster resilience in MENA countries and its impact on disaster losses

Abdullah Demir
Ali Ersin Dinçer
Nazire Nergiz Dincer
ResearchOpen Access08 Dec 2025
Scientific Reports

Volume: 15, P: 1-19
Shariah-compliant firms and firm leverage: evidence from firm-level time varying quasi experimental analysis for MENA countries

Talat Ulussever
Ömer Tuğsal Doruk
Ömer Faruk Tekdoğan
ResearchOpen Access24 Sept 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-9
Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Bacteria harness toxin-antitoxin systems to manipulate growth and evade stress. Using biochemistry, biophysics, and crystallography, the authors characterize a mechanism of antitoxin-induced autophosphorylation that can neutralize nucleotidyltransferase toxins of Mycobacterium tuberculosis.

Tom J. Arrowsmith
Xibing Xu
Tim R. Blower
ResearchOpen Access04 Sept 2024
Nature Communications

Volume: 15, P: 1-20
Intersectional biases in narratives produced by open-ended prompting of generative language models

People use generative language models to inform all aspects of their lives. Here, the authors examine synthetic narratives produced by open-ended prompting of generative language models and identify patterns of omission, subordination, and stereotyping against minoritized intersectional subgroups.

Evan Shieh
Faye-Marie Vassel
Thema Monroe-White
ResearchOpen Access08 Jan 2026
Nature Communications

Volume: 17, P: 1-20
Phosphorus transitions driven by cyclone biparjoy linked middle east North Africa (MENA) and Indian Thar Desert dust storm pathways in Asia’s largest grassland

Rupak Dey
Seema B. Sharma
Aliya Naz
ResearchOpen Access05 Feb 2025
Scientific Reports

Volume: 15, P: 1-18
Development of a composite drought indicator for operational drought monitoring in the MENA region

Karim Bergaoui
Makram Belhaj Fraj
Rachael McDonnell
ResearchOpen Access05 Mar 2024
Scientific Reports

Volume: 14, P: 1-16
Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells

The understanding of the mechanisms underlying the ability of disseminated tumor cells (DTCs) to form metastasis is incomplete. Here, by using high-resolution intravital imaging of the murine lung to track the fate of breast-derived DTCs, the authors show that macrophages within the primary tumor induce a pro-dissemination and pro-dormancy phenotype in tumor cells, favouring their extravasation in the lung.

Lucia Borriello
Anouchka Coste
David Entenberg
ResearchOpen Access02 Feb 2022
Nature Communications

Volume: 13, P: 1-19
National evidence on glucose-lowering medication use for diabetes from 62 low- and middle-income countries

Given rising diabetes prevalence globally, access to diabetes treatments is gaining urgency. Here, the authors show patterns of glucose-lowering medication use for diabetes across 62 low- and middle-income countries.

Felix Teufel
Pia Roddewig
Caroline Bulstra
ResearchOpen Access04 Aug 2025
Nature Communications

Volume: 16, P: 1-8
Perspectives on transport pathways of microplastics across the Middle East and North Africa (MENA) region

Sisi Pu
Hooralain Bushnaq
Ludovic F. Dumée
ReviewsOpen Access17 Nov 2024
npj Clean Water

Volume: 7, P: 1-23
NHSL3 controls single and collective cell migration through two distinct mechanisms

NHSL3 is the most recently identified gene of the Nance-Horan syndrome family. Here, the authors show that the gene encodes several protein isoforms that control both single and collective cell migration by interacting with specific effector proteins.

Nikita M. Novikov
Jinmei Gao
Alexis M. Gautreau
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-16
Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane

A family of cyclic lipopeptide natural products named lysocins was isolated from a soil bacteria sample and was found to exhibit antimicrobial actions. Genetic and biochemical evidence showed that lysocin E targets bacterial menaquinone.

Hiroshi Hamamoto
Makoto Urai
Kazuhisa Sekimizu
Research08 Dec 2014
Nature Chemical Biology

Volume: 11, P: 127-133
Tracking grid-level freshwater boundary exceedance along global supply chains from consumption to impact

Global consumption drives freshwater overuse at production sites along supply chains, of which 24% is outsourced via trade. Agricultural demand is a key driver, while manufacturing exports exacerbate water stress in emerging economies.

Siyu Hou
Jingwen Huo
Klaus Hubacek
ResearchOpen Access07 Apr 2025
Nature Water

Volume: 3, P: 439-448
Business-as-usual will lead to super and ultra-extreme heatwaves in the Middle East and North Africa

George Zittis
Panos Hadjinicolaou
Jos Lelieveld
ResearchOpen Access23 Mar 2021
npj Climate and Atmospheric Science

Volume: 4, P: 1-9
Prevalence, deaths and disability-adjusted life years due to Alzheimer’s disease and other dementias in Middle East and North Africa, 1990–2021

Fatemeh Amiri
Saeid Safiri
Ali-Asghar Kolahi
ResearchOpen Access27 Feb 2025
Scientific Reports

Volume: 15, P: 1-13
Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties

Bacteria produce several high molecular weight polysaccharides with ill-defined anti-adhesion properties. Here, the authors identified key molecular and biophysical determinants of active antibiofilm polysaccharides, opening new perspectives to identify or engineer new compounds able to control bacterial adhesion and biofilm formation.

Joaquín Bernal-Bayard
Jérôme Thiebaud
Jean-Marc Ghigo
ResearchOpen Access03 May 2023
Nature Communications

Volume: 14, P: 1-11
Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks

Ramesh Elango
Sameera Rashid
Nehad M. Alajez
ResearchOpen Access12 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-14
The burden of prostate cancer in the North Africa and Middle East Region from 1990 to 2021

Saeid Safiri
Ali Shamekh
Ali-Asghar Kolahi
ResearchOpen Access13 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
The burden of rheumatoid arthritis in the Middle East and North Africa region, 1990–2019

Seyed Ehsan Mousavi
Seyed Aria Nejadghaderi
Saeid Safiri
ResearchOpen Access11 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
Ectopic expression of cytosolic DHODH uncouples de novo pyrimidine biosynthesis from mitochondrial electron transport

Cytosolic ScURA uncouples de novo pyrimidine synthesis from mitochondrial electron transport, and rescues pyrimidine production and cell proliferation under pharmacological or genetic mETC disruption.

Andrea Curtabbi
Sara Natalia Jaroszewicz
José Antonio Enríquez
ResearchOpen Access17 Feb 2026
Nature Metabolism

P: 1-13
Burden of diseases and injuries attributable to alcohol consumption in the Middle East and North Africa region, 1990–2019

Saeid Safiri
Seyed Aria Nejadghaderi
Ali-Asghar Kolahi
ResearchOpen Access11 Nov 2022
Scientific Reports

Volume: 12, P: 1-13
Trends and projection of incidence, mortality, and disability-adjusted life years of HIV in the Middle East and North Africa (1990–2030)

Zahra Khorrami
Mohammadreza Balooch Hasankhani
Hamid Sharifi
ResearchOpen Access24 Aug 2023
Scientific Reports

Volume: 13, P: 1-16
Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes

Antimicrobial resistance genes that have been mobilized between bacterial species represent a subset of the naturally occurring resistome. Here, the authors compare the abundance, diversity and geographical patterns of acquired resistance genes with latent resistance genes in global sewage metagenomes.

Hannah-Marie Martiny
Patrick Munk
Frank M. Aarestrup
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-12
Genetic modifiers of APOE-ε4-associated cognitive decline

The APOE-ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease, but it is not deterministic. Here, the authors show that common genetic variation changes how APOE-ε4 influences cognition.

Alex G. Contreras
Skylar Walters
Timothy J. Hohman
ResearchOpen Access20 Feb 2026
Nature Communications

P: 1-17
The global nexus of food–trade–water sustaining environmental flows by 2050

The challenges of meeting food, water and energy needs are interconnected, requiring integrated assessments of land use, socioeconomic policies and climate change. This study assesses the required increases in water, trade and agricultural land needed to double food production by 2050.

A. V. Pastor
A. Palazzo
F. Ludwig
Research13 May 2019
Nature Sustainability

Volume: 2, P: 499-507
Kidney cancer in the Middle East and North Africa region: a 30-year analysis (1990–2019)

Saeid Safiri
Kamaleddin Hassanzadeh
Ali-Asghar Kolahi
ResearchOpen Access14 Jun 2024
Scientific Reports

Volume: 14, P: 1-10
Burden of diseases due to high systolic blood pressure in the Middle East and North Africa region from 1990 to 2019

Saeid Safiri
Seyed Ehsan Mousavi
Mohammad Reza Beyranvand
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-11
The burden of schizophrenia in the Middle East and North Africa region, 1990–2019

Saeid Safiri
Maryam Noori
Ali-Asghar Kolahi
ResearchOpen Access27 Apr 2024
Scientific Reports

Volume: 14, P: 1-13
The burden of colorectal cancer attributable to dietary risk in Middle East and North African from 1990 to 2019

Yahya Pasdar
Fatemeh Khosravi Shadmani
Mitra Darbandi
ResearchOpen Access20 Nov 2023
Scientific Reports

Volume: 13, P: 1-9
Burden of polycystic ovary syndrome in the Middle East and North Africa region, 1990–2019

Kimia Motlagh Asghari
Seyed Aria Nejadghaderi
Saeid Safiri
ResearchOpen Access29 Apr 2022
Scientific Reports

Volume: 12, P: 1-11
Burden of diseases attributable to excess body weight in the Middle East and North Africa region, 1990–2019

Seyed Aria Nejadghaderi
Jessica A. Grieger
Siamak Sabour
ResearchOpen Access20 Nov 2023
Scientific Reports

Volume: 13, P: 1-12
Virtual contact improves intergroup relations between non-Muslim American and Muslim students from the Middle East, North Africa and Southeast Asia in a field quasi-experiment

Virtual contact between U.S. non-Muslim and Muslim students from MENA and SE Asia regions demonstrates that online interactions can effectively reduce prejudice and dehumanization, offering a scalable solution for improving intergroup relations.

Shira Hebel-Sela
Boaz Hameiri
Emile Bruneau
ResearchOpen Access03 Mar 2025
Communications Psychology

Volume: 3, P: 1-11
Unique perspectives about men’s awareness of BRCA1/2 genetic testing in primary care

Caryn Scheinberg Andrews
Istabraq Ibrahim
Anita Noble
ResearchOpen Access11 Feb 2026
Scientific Reports

Volume: 16, P: 1-8
The burden of stroke and its attributable risk factors in the Middle East and North Africa region, 1990–2019

Mehran Jaberinezhad
Mehdi Farhoudi
Saeid Safiri
ResearchOpen Access17 Feb 2022
Scientific Reports

Volume: 12, P: 1-11
Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens

(Meta)genomic mining, bioinformatic prediction and chemical synthesis reveal biosynthetic gene clusters encoding structurally new menaquinone-binding antibiotics that are active against multidrug-resistant Staphylococcus aureus in vivo and Mycobacterium tuberculosis in vitro.

Lei Li
Bimal Koirala
Sean F. Brady
Research23 Dec 2021
Nature Microbiology

Volume: 7, P: 120-131
Phosphorus for Sustainable Development Goal target of doubling smallholder productivity

Phosphorous is limited in many tropical soils. This study finds that, despite such limitation, sub-Saharan Africa is on track to nearly doubling productivity on smallholder farms while some regions will require almost 40% more phosphorous applied between 2015 and 2030.

C. Langhans
A. H. W. Beusen
A. F. Bouwman
ResearchOpen Access22 Nov 2021
Nature Sustainability

Volume: 5, P: 57-63
The national and provincial burden of transport injuries in Iran between 1990 and 2021

Amin Abbasi
Moloud Balafar
Hassan Soleimanpour
ResearchOpen Access23 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
Doubling of the global freshwater footprint of material production over two decades

Many of the materials that our everyday lives rely on come with a hidden freshwater cost during production. The embodied water in materials has surged in material production with the potential to exacerbate regional water scarcity.

Yao Wang
Fengmei Ma
Stephan Lutter
Research30 Oct 2025
Nature Sustainability

Volume: 8, P: 1554-1566
Analysis of the 2024 Hajj heat event and future temperature extremes in Mecca

George Zittis
Tommaso Alberti
Jos Lelieveld
ReviewsOpen Access20 Dec 2025
npj Natural Hazards

Volume: 2, P: 1-8
MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding

Bacteria can control their growth using internal toxins regulated by antitoxins. Here, the authors show MenT toxins from Mycobacterium tuberculosis work by modifying tRNAs, and asymmetric antitoxin binding blocks toxin activity.

Xibing Xu
Ben Usher
Pierre Genevaux
ResearchOpen Access17 Aug 2023
Nature Communications

Volume: 14, P: 1-18
Sustained Oscillations in a Catalytic Chemical System

R. A. SPANGLER
F. M. SNELL
Research01 Jul 1961
Nature

Volume: 191, P: 457-458
Halitosis among users of electronic nicotine delivery systems in a multi-center cross-sectional study

Saadi M. Saleh
Abdelrahman Shata
Omar Hama Ahmed
ResearchOpen Access25 Jun 2025
Scientific Reports

Volume: 15, P: 1-8
A practical approach for adoption of a hub and spoke model for cell and gene therapies in low- and middle-income countries: framework and case studies

Shadi Saleh
Omar Dabbous
Sean Tunis
ReviewsOpen Access30 Oct 2023
Gene Therapy

Volume: 31, P: 1-11
Age-impaired remyelination is associated with dysregulated microglial transitions

Microglial states throughout remyelination are incompletely understood. Here, the authors show that microglia form several states during the early stages of remyelination that coalesce into a partially resolved state that is dysregulated with age.

Sameera Zia
Marianela E. Traetta
Jason R. Plemel
ResearchOpen Access12 Nov 2025
Nature Communications

Volume: 16, P: 1-24
Green energy and steel imports reduce Europe’s net-zero infrastructure needs

This study examines cost reductions, volumes, & vectors of green energy imports to Europe, showing diminishing returns at higher volumes and a preference for methanol, steel and hydrogen imports.

Fabian Neumann
Johannes Hampp
Tom Brown
ResearchOpen Access12 Jun 2025
Nature Communications

Volume: 16, P: 1-19
COVID-19 vaccination and major cardiovascular and haematological adverse events in Abu Dhabi: retrospective cohort study

Adverse cardiovascular and haematological events following COVID-19 vaccination have been reported, leading to safety concerns. Here, the authors find no evidence for increased incidence of these events within 21 days of BIBP-CorV or BNT162b2 vaccination in electronic health record data from Abu Dhabi.

Marco A. F. Pimentel
Maaz Shaikh
Shadab Khan
ResearchOpen Access28 Jun 2024
Nature Communications

Volume: 15, P: 1-8
An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis

R Lara
F A Mauri
O E Pardo
Research21 Mar 2011
Oncogene

Volume: 30, P: 3513-3521
Structure and community assembly of rare bacterial community in sediments of Sancha Lake

Yong Li
Yajie Li
Sidan Gong
ResearchOpen Access24 Dec 2025
Scientific Reports

Volume: 16, P: 1-15
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population

Loulia Bader
Ahmad Mahfouz
Hazem Elewa
Research25 Oct 2019
The Pharmacogenomics Journal

Volume: 20, P: 277-284
Reply to: Why fossil fuel producer subsidies matter

Jessica Jewell
Johannes Emmerling
Detlef van Vuuren
Research05 Feb 2020
Nature

Volume: 578, P: E5-E7

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