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Showing 1–50 of 57 results

Advanced filters: Author: Gaurav Sharma Clear advanced filters

Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

Maximilian Zenk
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Direct shoot regeneration and gene expression profiling for optimized picroside-I biosynthesis in Picrorhiza Kurroa

Sonia Kumari Shishodia
Arjun Chauhan
Gholamreza Abdi
ResearchOpen Access02 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
Optimization of steel anchor pile configurations for enhanced pullout resistance in expansive soil foundations

Abhishek Sharma
Anjana Kumari
Ankush Mehta
ResearchOpen Access29 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Host range expansion of Helicoverpa armigera to apple orchards in the Himalayan region

Chander Singh
Subhash Chander Verma
Ojas Chauhan
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-8
Effects of biochar amendment at various soil depths on maize roots and growth indices

S. Gaurav
B. Diptanu
Vishnu D. Rajput
ResearchOpen Access20 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Experimental and numerical investigation on heat dissipation capability of micro-pillar textured cutting tools

Gaurav Saraf
Gaurav Sharma
Chandrakant K. Nirala
ResearchOpen Access10 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
SARS-CoV-2 virulence factor ORF3a blocks lysosome function by modulating TBC1D5-dependent Rab7 GTPase cycle

SARS-CoV-2 uses the host endolysosomal system for replication and egress. Here the authors show that SARS-CoV-2 virulence factor ORF3a localizes to the late endocytic compartments of the host cell to disrupt Rab7 GTP to GDP cycling and block lysosome function in cargo degradation, while activated Rab7 promotes virus replication.

Kshitiz Walia
Abhishek Sharma
Amit Tuli
ResearchOpen Access06 Mar 2024
Nature Communications

Volume: 15, P: 1-24
Discovering geroprotectors through the explainable artificial intelligence-based platform AgeXtend

Arora et al. present AgeXtend, an explainable artificial intelligence-based platform that leverages bioactivity data to predict geroprotectors. They validate potential geroprotectors identified using this platform in yeast, worm and senescence assays.

Sakshi Arora
Aayushi Mittal
Gaurav Ahuja
Research03 Dec 2024
Nature Aging

Volume: 5, P: 144-161
Innovative strategies for managing hallucinations by exploring effects of tDCS on source monitoring abilities

Gaurav Sharma
Vinay Chitturi
Ragini D. Singh
ResearchOpen Access17 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Federated learning enables big data for rare cancer boundary detection

Federated ML (FL) provides an alternative to train accurate and generalizable ML models, by only sharing numerical model updates. Here, the authors present the largest FL study to-date to generate an automatic tumor boundary detector for glioblastoma.

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access05 Dec 2022
Nature Communications

Volume: 13, P: 1-17
RUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning

Lysosomes move along microtubule tracks, and Arl8b is known to stimulate their anterograde transport. Here, the authors identified RUFY3 as an Arl8b effector that interacts with dynein-dynactin to drive retrograde transport and perinuclear lysosome positioning.

Gaurav Kumar
Prateek Chawla
Amit Tuli
ResearchOpen Access21 Mar 2022
Nature Communications

Volume: 13, P: 1-21
Development of rare earth element-based hybrid aluminium composites using stir casting process

Gaurav Sapkota
Ranjan Kumar Ghadai
Kanak Kalita
ResearchOpen Access13 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni

The CsrA protein binds to and represses translation of certain bacterial mRNAs. Here, Dugar et al. show for the human pathogen Campylobacter jejunithat the major flagellin mRNA acts as both a target and a regulatory 'sponge' for CsrA, and is localized at the cell poles in a translation-dependent manner.

Gaurav Dugar
Sarah L. Svensson
Cynthia M. Sharma
ResearchOpen Access27 May 2016
Nature Communications

Volume: 7, P: 1-18
Sense of agency for intracortical brain–machine interfaces

Serino et al. studied the sense of agency for actions generated via a brain–machine interface. They show that primary motor cortex encodes not only motor and sensory signals, but also subjective agency signals, enabling improved brain–machine interface proficiency.

Andrea Serino
Marcia Bockbrader
Olaf Blanke
Research19 Jan 2022
Nature Human Behaviour

Volume: 6, P: 565-578
Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques

SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.

Pragya D. Yadav
Raches Ella
Balram Bhargava
ResearchOpen Access02 Mar 2021
Nature Communications

Volume: 12, P: 1-11
Complex rearrangement in TBC1D4 in an individual with diabetes due to severe insulin resistance syndrome

Avivit Cahn
Hagar Mor-Shaked
Tamar Harel
Research12 Dec 2023
European Journal of Human Genetics

Volume: 32, P: 232-237
HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8⁺ T-cell infiltration into tumors

Lack of CD8⁺ T-cell infiltration into solid tumors is associated with poor responsiveness to immune checkpoint therapy (ICT). Here, the authors show that blocking the phosphorylation of HRS to reduce the induction of immunosuppressive exosomes promotes CD8⁺ T-cell infiltration into tumors and enhances the efficacy of ICT in mouse melanoma models.

Lei Guan
Bin Wu
Wei Guo
ResearchOpen Access14 Jul 2022
Nature Communications

Volume: 13, P: 1-12
Impact of lanthanum doping on crystal structure and magnetic anisotropy of Mn-Zn soft nanoferrites

Gaurav Katoch
Gazal Sharma
A. Johnson Santhosh
ResearchOpen Access05 Apr 2025
Scientific Reports

Volume: 15, P: 1-15
Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression

Proliferation of cardiomyocytes typically ceases shortly after birth. Here the authors show that decreasing fatty-acid oxidation extends the perinatal cardiomyocyte proliferative window and can reintroduce cell-cycle activity in adult cardiomyocytes.

Alisson C. Cardoso
Nicholas T. Lam
Hesham A. Sadek
Research20 Feb 2020
Nature Metabolism

Volume: 2, P: 167-178
A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

The response to respiratory virus exposure can currently not be predicted by pre- or early post-exposure molecular signatures. Here, the authors conduct a community-based analysis of blood gene expression from healthy individuals exposed to respiratory viruses and provide predictive models and biological insight into the physiological response.

Slim Fourati
Aarthi Talla
Solveig K. Sieberts
ResearchOpen Access24 Oct 2018
Nature Communications

Volume: 9, P: 1-11
The lag in SARS-CoV-2 genome submissions to GISAID

Kishan Kalia
Gayatri Saberwal
Gaurav Sharma
Correspondence10 Aug 2021
Nature Biotechnology

Volume: 39, P: 1058-1060
Driver identification in advanced transportation systems using osprey and salp swarm optimized random forest model

Akshat Gaurav
Brij B. Gupta
Kwok Tai Chui
ResearchOpen Access19 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Synergistic mechanisms of novel Z-Scheme N,S co-doped biochar-based Ag₃PO₄ composites for efficient removal of norfloxacin

Tongtong Wang
Amit Kumar
Hui Shi
ResearchOpen Access28 Sept 2024
npj Clean Water

Volume: 7, P: 1-16
A real-world study of wearable sensors in Parkinson’s disease

Jamie L. Adams
Karthik Dinesh
Gaurav Sharma
ResearchOpen Access29 Nov 2021
npj Parkinson's Disease

Volume: 7, P: 1-8
Elimination of a ligand gating site generates a supersensitive olfactory receptor

Kanika Sharma
Gaurav Ahuja
Sigrun I. Korsching
ResearchOpen Access21 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Pesticide Residues in Peri-Urban Bovine Milk from India and Risk Assessment: A Multicenter Study

J. P. S. Gill
J. S. Bedi
Manish Kakkar
ResearchOpen Access15 May 2020
Scientific Reports

Volume: 10, P: 1-11
Meeting brain–computer interface user performance expectations using a deep neural network decoding framework

Intracortical activity data recorded over 2 years in a tetraplegic patient is used to develop an artificial intelligence algorithm that achieves fast, accurate, and stable movement decoding to reenable real-time control of the paralyzed forearm.

Michael A. Schwemmer
Nicholas D. Skomrock
David A. Friedenberg
Research24 Sept 2018
Nature Medicine

Volume: 24, P: 1669-1676
Genome wide transcriptome profiling of Fusarium oxysporum f sp. ciceris conidial germination reveals new insights into infection-related genes

Mamta Sharma
Anindita Sengupta
Rajeev K Varshney
ResearchOpen Access17 Nov 2016
Scientific Reports

Volume: 6, P: 1-11
Restoring cortical control of functional movement in a human with quadriplegia

Signals recorded from motor cortex—through an intracortical implant—can be linked in real-time to activation of forearm muscles to restore movement in a paralysed human.

Chad E. Bouton
Ammar Shaikhouni
Ali R. Rezai
Research13 Apr 2016
Nature

Volume: 533, P: 247-250
Glucose-6-phosphate dehydrogenase is critical for suppression of cardiac hypertrophy by H₂S

Aastha Chhabra
Shalini Mishra
Manish Sharma
ResearchOpen Access01 Feb 2018
Cell Death Discovery

Volume: 4, P: 1-16
APOBEC3H polymorphisms and susceptibility to HIV-1 infection in an Indian population

Taeko K Naruse
Daisuke Sakurai
Akinori Kimura
Research12 Nov 2015
Journal of Human Genetics

Volume: 61, P: 263-265
The ex vivo human translaminar autonomous system to study spaceflight associated neuro-ocular syndrome pathogenesis

Michael Peng
Stacy M. Curry
Tasneem P. Sharma
ResearchOpen Access28 Oct 2022
npj Microgravity

Volume: 8, P: 1-14
SwiftReg cluster registration automatically reduces flow cytometry data variability including batch effects

Rebhahn et al. develop swiftReg that automatically corrects undesired sources of variability of flow cytometry data. To identify batch variation, this method registers an internal standard or consensus sample from each batch and applies the resulting registration shifts to individual samples, reducing the batch variation while preserving biological differences.

Jonathan A. Rebhahn
Sally A. Quataert
Tim R. Mosmann
ResearchOpen Access07 May 2020
Communications Biology

Volume: 3, P: 1-14
Using an Artificial Neural Bypass to Restore Cortical Control of Rhythmic Movements in a Human with Quadriplegia

Gaurav Sharma
David A. Friedenberg
Chad Bouton
ResearchOpen Access23 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
Neuroprosthetic-enabled control of graded arm muscle contraction in a paralyzed human

David A. Friedenberg
Michael A. Schwemmer
Gaurav Sharma
ResearchOpen Access21 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Author Correction: Federated learning enables big data for rare cancer boundary detection

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
Amendments and CorrectionsOpen Access26 Jan 2023
Nature Communications

Volume: 14, P: 1-2
Iron-Overload triggers ADAM-17 mediated inflammation in Severe Alcoholic Hepatitis

Jaswinder Singh Maras
Sukanta Das
Shiv Kumar Sarin
ResearchOpen Access06 Jul 2018
Scientific Reports

Volume: 8, P: 1-14
Author Correction: Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

Yuhan Jiang
Zhen Li
Jian Hu
Amendments and CorrectionsOpen Access24 Oct 2023
Communications Biology

Volume: 6, P: 1
Modeling of two-stage anaerobic onsite wastewater sanitation system to predict effluent soluble chemical oxygen demand through machine learning

Rajshree Mathur
Meena Kumari Sharma
Koppula Srinivas Rao
ResearchOpen Access21 Jan 2024
Scientific Reports

Volume: 14, P: 1-14
Evaluation of micronutrient profile of North Indian children with cystic fibrosis: a case–control study

Krishan Yadav
Meenu Singh
Anil Kumar Bhalla
Research06 Apr 2014
Pediatric Research

Volume: 75, P: 762-766
Pre-transplant myeloid and immune suppression, upfront plerixafor mobilization and post-transplant cyclophosphamide: novel strategy for haploidentical transplant in sickle cell disease

Gaurav Kharya
Atish Bakane
Archana Rauthan
Research15 Sept 2020
Bone Marrow Transplantation

Volume: 56, P: 492-504
Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells

Shakti Sagar
Md Imam Faizan
Soumya Sinha Roy
ResearchOpen Access13 May 2023
Cell Death & Disease

Volume: 14, P: 1-19
Green synthesis of peptide functionalized reduced graphene oxide (rGO) nano bioconjugate with enhanced antibacterial activity

Shubhi Joshi
Ruby Siddiqui
Avneet Saini
ResearchOpen Access10 Jun 2020
Scientific Reports

Volume: 10, P: 1-11
Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity

An integrated experimental and computational approach reveals an ion selectivity filter in multi-metal transporter ZIP8 that is rationally engineered to increase preference toward Zn²⁺ over Cd²⁺.

Yuhan Jiang
Zhen Li
Jian Hu
ResearchOpen Access26 Jul 2023
Communications Biology

Volume: 6, P: 1-15
Thiourea priming enhances salt tolerance through co-ordinated regulation of microRNAs and hormones in Brassica juncea

Ashish Kumar Srivastava
Gaurav Sablok
Penna Suprasanna
ResearchOpen Access06 Apr 2017
Scientific Reports

Volume: 7, P: 1-15
Correction: Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines

Luciane T. Kagohara
Fernando Zamuner
Elana J. Fertig
Amendments and Corrections21 Jul 2020
British Journal of Cancer

Volume: 123, P: 1582-1583
Differential responses of chicken monocyte-derived dendritic cells infected with Salmonella Gallinarum and Salmonella Typhimurium

Degpal Singh
Mithilesh Singh
Tapas Kumar Goswami
ResearchOpen Access26 Aug 2021
Scientific Reports

Volume: 11, P: 1-13
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines

Luciane T. Kagohara
Fernando Zamuner
Elana J. Fertig
ResearchOpen Access04 May 2020
British Journal of Cancer

Volume: 123, P: 101-113
Real-time hyperpolarized ¹³C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4–double knockout mouse livers

Gaurav Sharma
Cheng-Yang Wu
Chalermchai Khemtong
ResearchOpen Access11 Nov 2019
Scientific Reports

Volume: 9, P: 1-11
Agricultural wastes as a resource of raw materials for developing low-dielectric glass-ceramics

Satwinder Singh Danewalia
Gaurav Sharma
K. Singh
ResearchOpen Access18 Apr 2016
Scientific Reports

Volume: 6, P: 1-12

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