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Showing 1–5 of 5 results
Advanced filters: Author: Geoffrey Schiebinger Clear advanced filters

  • The contribution of cell-extrinsic factors during cellular reprogramming to human induced pluripotent stem cells has long been overlooked. Here, the authors show functional protein communication between reprogramming intermediates and the re-shaping of a permissive extracellular environment.

    • Francesco Panariello
    • Onelia Gagliano
    • Nicola Elvassore
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve our understanding of development.

    • Aden Forrow
    • Geoffrey Schiebinger
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • This Resource presents an atlas classifying the age-related changes in human hematopoietic stem and progenitor cells from gestation through aging.

    • Hojun Li
    • Parker Côté
    • R. Grant Rowe
    Research
    Nature Methods
    Volume: 22, P: 422-434

  • The optimal transport mathematical framework can be used to describe how source populations, such as populations of single cells, can morph into another target population. In this Primer, Bunne et al. describe how optimal transport theory is used for analysing single-cell data.

    • Charlotte Bunne
    • Geoffrey Schiebinger
    • Marco Cuturi
    Reviews
    Nature Reviews Methods Primers
    Volume: 4, P: 1-21