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Giant electrocaloric effect in high-polar-entropy perovskite oxides

Targeted multielement substitution of a lead-free relaxor ferroelectric perovskite distorts the lattice structure and induces strong polar disorder, leading to high-polar-entropy ferroelectric oxides with a high electrocaloric effect and long lifetime.

Feihong Du
Tiannan Yang
Xiaoshi Qian
Research09 Apr 2025
Nature

Volume: 640, P: 924-930
Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families

Using a single strategy to make a number of related intermediates is a useful strategy in the total synthesis. Here, the authors report the synthesis of a number of natural products, employing two diastereomerically complementary metal-catalyzed cyclizations as the key step to access a number of frameworks.

Zhanchao Meng
Haixin Yu
Ang Li
ResearchOpen Access04 Feb 2015
Nature Communications

Volume: 6, P: 1-8
Bright and photostable yellow fluorescent proteins for extended imaging

Yellow fluorescent proteins (YFPs) photobleach rapidly, restricting microscopy experiments. Here, the authors report mGold2s and mGold2t, YFPs that extend imaging durations up to 25 times longer than standard probes without sacrificing brightness.

Jihwan Lee
Shujuan Lai
François St-Pierre
ResearchOpen Access04 Apr 2025
Nature Communications

Volume: 16, P: 1-16
Correction: Corrigendum: Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

Kexin Chen
Hongxia Ma
Qingyi Wei
Amendments and Corrections17 Dec 2014
Nature Communications

Volume: 5, P: 1
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

The genomic epidemiology of Acinetobacter baumannii, which is rising in virulence and multidrug resistance, was explored. This study examined bloodstream infection isolates from Chinese patients in 2011–2021, revealing increased genetic diversity and dominance of highly virulent ST208.

Qixia Luo
Mengru Chang
Yonghong Xiao
ResearchOpen Access14 Apr 2025
Nature Communications

Volume: 16, P: 1-17
Reduction of bulk and surface defects in inverted methylammonium- and bromide-free formamidinium perovskite solar cells

The efficiency and stability of methylammonium- and bromide-free perovskite inverted solar cells need improvement. Now, Chen et al. combine a Lewis-based additive with a fluorocarbon-modified ammonium salt to reduce defects in the perovskite, increasing the device performance.

Rui Chen
Jianan Wang
Wei Chen
Research03 Jul 2023
Nature Energy

Volume: 8, P: 839-849
Modulation of perovskite degradation with multiple-barrier for light-heat stable perovskite solar cells

The long-term stability of perovskite solar cells remains a critical challenge for the commercialization of the technology. Here, the authors adopt a non-noble metal/metal oxide/polymer multiple-barrier to suppress device degradation, achieving long-term stability in encapsulated p-i-n devices.

Jing Zhou
Zonghao Liu
Wei Chen
ResearchOpen Access30 Sept 2023
Nature Communications

Volume: 14, P: 1-11
AMPK-mediated activation of MCU stimulates mitochondrial Ca²⁺ entry to promote mitotic progression

Zhao et al. find that AMPK phosphorylates and activates the mitochondrial Ca²⁺ uniporter in response to low energy status in mitosis, allowing Ca²⁺ entry into mitochondria to boost mitochondrial respiration.

Haixin Zhao
Teng Li
Xin Pan
Research11 Mar 2019
Nature Cell Biology

Volume: 21, P: 476-486
Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

Ovarian cancer is common among women and is the leading cause of death from gynaecological malignancies. Here the authors identify two previously unknown genetic variants that increase the risk of epithelial ovarian cancer in Han Chinese women.

Kexin Chen
Hongxia Ma
Qingyi Wei
Research19 Aug 2014
Nature Communications

Volume: 5, P: 1-8
ZDHHC1 downregulates LIPG and inhibits colorectal cancer growth via IGF2BP1 Palmitoylation

Qun Zhang
Zhouyuan Du
Tao Liu
ResearchOpen Access28 Jul 2024
Cancer Gene Therapy

Volume: 31, P: 1427-1437
Author Correction: Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Ting Li
Dingyi Lu
Xin Pan
Amendments and CorrectionsOpen Access17 Mar 2022
Nature Communications

Volume: 13, P: 1
Genomes of 211 Actinomycete Strains from Diverse Environments

Yue Liu
Zhengjiao Liang
Haixin Chen
ResearchOpen Access15 Jul 2025
Scientific Data

Volume: 12, P: 1-5
Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

Developing multi-cancer early detection (MCED) tests based on cfDNA or protein markers holds great promise for effective cancer screening. Here, the authors show a sensitive, non-invasive pan-cancer detection method that concurrently detects the oncofetal chondroitin sulfate (ofCS) glycans and its protein backbone in plasma.

Pei-Fen Zhang
Zi-Yi Wu
Wei-Hua Jia
ResearchOpen Access06 Feb 2023
Nature Communications

Volume: 14, P: 1-12
The asparagus genome sheds light on the origin and evolution of a young Y chromosome

Several models have been proposed to explain the emergence of sex chromosomes. Here, through comparative genomics and mutant analysis, Harkess et al. show that linked but separate genes on the Y chromosome are responsible for sex determination in Asparagus, supporting a two-gene model for sex chromosome evolution.

Alex Harkess
Jinsong Zhou
Guangyu Chen
ResearchOpen Access02 Nov 2017
Nature Communications

Volume: 8, P: 1-10
Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii

Tree peony (Paeonia ostii) has the largest chromosome of any sequenced plants to date. Here, the authors assemble its genome and reveal the association of a list of candidate genes with fatty acid biosynthesis and the possible contribution of transposon and histone expansion to maintain the giga-chromosomes.

Junhui Yuan
Sanjie Jiang
Yonghong Hu
ResearchOpen Access28 Nov 2022
Nature Communications

Volume: 13, P: 1-16
Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO

The two-component regulatory system VraRS regulates transcription of penicillin-binding protein 2 in response to cell wall antimicrobials. Here, Lu et al. show that an enzyme from the wall teichoic acid biosynthetic pathway of MRSA can also modulate the expression of virulence factors such as Staphylococcal protein A via VraRS.

Yunfu Lu
Feifei Chen
Lefu Lan
ResearchOpen Access22 Mar 2023
Nature Communications

Volume: 14, P: 1-19
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Qing Lan and colleagues report the results of a genome-wide association study of lung cancer in never-smoking women from Asia. They identify three new susceptibility loci and confirm three other previously reported associations.

Qing Lan
Chao A Hsiung
Nathaniel Rothman
Research11 Nov 2012
Nature Genetics

Volume: 44, P: 1330-1335
Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Here the authors show that the Koolen-de Vries syndrome associated gene KANSL1 modulates autophagosome-lysosome fusion via transcriptional regulation of autophagosomal gene Syntaxin17, and that 13-cis retinoic acid can reverses mitophagic defects and neurobehavioural abnormalities of mice lacking Kansl1.

Ting Li
Dingyi Lu
Xin Pan
ResearchOpen Access17 Feb 2022
Nature Communications

Volume: 13, P: 1-16
The effect of aging on glucose metabolism improvement after Roux-en-Y gastric bypass in type 2 diabetes rats

Weijie Chen
Haixin Yin
Xiaodong He
ResearchOpen Access23 Dec 2022
Nutrition & Diabetes

Volume: 12, P: 1-6
Meta-analysis of soil mercury accumulation by vegetables

Haixin Yu
Jing Li
Yaning Luan
ResearchOpen Access19 Jan 2018
Scientific Reports

Volume: 8, P: 1-10
Colloidal crystal engineering with metal–organic framework nanoparticles and DNA

Colloidal crystals assembled from nanoscale building blocks are powerful designer materials with diverse functionalities. Here, the authors describe a colloidal crystal engineering strategy to prepare hierarchical structures from metal–organic framework nanoparticles and DNA which retain permanent porosity and catalytic activity.

Shunzhi Wang
Sarah S. Park
Chad A. Mirkin
ResearchOpen Access19 May 2020
Nature Communications

Volume: 11, P: 1-8
Pollen magnetofection for genetic modification with magnetic nanoparticles as gene carriers

Current genetic modification methods require regeneration using tissue culture. This study now reports a type of transformation technology, pollen magnetofection, that allows production of transgenic seeds in multiple species in a fast, culture-free manner.

Xiang Zhao
Zhigang Meng
Haixin Cui
Research27 Nov 2017
Nature Plants

Volume: 3, P: 956-964
A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China

Authors carry out a genomic analysis of carbapenem-resistant Klebsiella pneumoniae bloodstream isolates, noting subclonal expansion, associated with the emergence of a hypervirulent subpopulation.

Kai Zhou
Chun-Xu Xue
Yonghong Xiao
ResearchOpen Access28 Apr 2023
Nature Communications

Volume: 14, P: 1-14
Alternative mRNA polyadenylation regulates macrophage hyperactivation via the autophagy pathway

Yunzhu Chen
Baiwen Chen
Hua-Bing Li
ResearchOpen Access13 Nov 2024
Cellular & Molecular Immunology

Volume: 21, P: 1522-1534
MethAgingDB: a comprehensive DNA methylation database for aging biology

Siyu Li
Songming Tang
Shengquan Chen
ResearchOpen Access14 Jul 2025
Scientific Data

Volume: 12, P: 1-10
Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization

Li Zhang, Zhimin Cui, and Qianqian Li et al. compare the infectivity, host tropism, and antigenicity of 10 SARS-CoV-2 variants using a VSV-based pseudovirus system. Their results suggest that variants carrying E484K display the most significant reduction in sensitivity to neutralization, and may provide further insight into the development of relevant therapeutics for SARS-CoV-2 infection.

Li Zhang
Zhimin Cui
Youchun Wang
ResearchOpen Access13 Oct 2021
Communications Biology

Volume: 4, P: 1-10
The Developmental Process of the Growing Motile Ciliary Tip Region

Matthew J. Reynolds
Tanaporn Phetruen
Haixin Sui
ResearchOpen Access22 May 2018
Scientific Reports

Volume: 8, P: 1-10
CarcinoPred-EL: Novel models for predicting the carcinogenicity of chemicals using molecular fingerprints and ensemble learning methods

Li Zhang
Haixin Ai
Hongsheng Liu
ResearchOpen Access18 May 2017
Scientific Reports

Volume: 7, P: 1-14
Multicenter and multimodal imaging study reveals rare fundus lesions in patients after SARS-CoV-2 infection

Guangqi An
Bo Lei
Liping Du
ResearchOpen Access22 Jun 2024
Scientific Reports

Volume: 14, P: 1-12
MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2

Weiwei Yan
Qiuying Han
Tao Zhou
ResearchOpen Access30 Apr 2022
British Journal of Cancer

Volume: 127, P: 612-623
The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer

Liangliang Ren
Xingrong Qing
Jun Li
ResearchOpen Access26 Aug 2023
Cell Death & Disease

Volume: 14, P: 1-15
Preliminary effectiveness of breast cancer screening among 1.22 million Chinese females and different cancer patterns between urban and rural women

Yubei Huang
Hongji Dai
Kexin Chen
ResearchOpen Access20 Dec 2016
Scientific Reports

Volume: 6, P: 1-10
Interrogation of gender disparity uncovers androgen receptor as the transcriptional activator for oncogenic miR-125b in gastric cancer

Ben Liu
Meng Zhou
Kexin Chen
ResearchOpen Access04 May 2021
Cell Death & Disease

Volume: 12, P: 1-22
Genome-wide association and functional interrogation identified a variant at 3p26.1 modulating ovarian cancer survival among Chinese women

Hongji Dai
Xinlei Chu
Kexin Chen
ResearchOpen Access21 Dec 2021
Cell Discovery

Volume: 7, P: 1-17
A salivary EF-hand calcium-binding protein of the brown planthopper Nilaparvata lugens functions as an effector for defense responses in rice

Wenfeng Ye
Haixin Yu
Yonggen Lou
ResearchOpen Access18 Jan 2017
Scientific Reports

Volume: 7, P: 1-12

Search

Giant electrocaloric effect in high-polar-entropy perovskite oxides

Total synthesis and antiviral activity of indolosesquiterpenoids from the xiamycin and oridamycin families

Bright and photostable yellow fluorescent proteins for extended imaging

Correction: Corrigendum: Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

Reduction of bulk and surface defects in inverted methylammonium- and bromide-free formamidinium perovskite solar cells

Modulation of perovskite degradation with multiple-barrier for light-heat stable perovskite solar cells

AMPK-mediated activation of MCU stimulates mitochondrial Ca²⁺ entry to promote mitotic progression

Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women

ZDHHC1 downregulates LIPG and inhibits colorectal cancer growth via IGF2BP1 Palmitoylation

Author Correction: Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Genomes of 211 Actinomycete Strains from Diverse Environments

Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

The asparagus genome sheds light on the origin and evolution of a young Y chromosome

Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii

Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

The effect of aging on glucose metabolism improvement after Roux-en-Y gastric bypass in type 2 diabetes rats

Meta-analysis of soil mercury accumulation by vegetables

Colloidal crystal engineering with metal–organic framework nanoparticles and DNA

Pollen magnetofection for genetic modification with magnetic nanoparticles as gene carriers

A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China

Alternative mRNA polyadenylation regulates macrophage hyperactivation via the autophagy pathway

MethAgingDB: a comprehensive DNA methylation database for aging biology

Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization

The Developmental Process of the Growing Motile Ciliary Tip Region

CarcinoPred-EL: Novel models for predicting the carcinogenicity of chemicals using molecular fingerprints and ensemble learning methods

Multicenter and multimodal imaging study reveals rare fundus lesions in patients after SARS-CoV-2 infection

MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2

The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer

Preliminary effectiveness of breast cancer screening among 1.22 million Chinese females and different cancer patterns between urban and rural women

Interrogation of gender disparity uncovers androgen receptor as the transcriptional activator for oncogenic miR-125b in gastric cancer

Genome-wide association and functional interrogation identified a variant at 3p26.1 modulating ovarian cancer survival among Chinese women

A salivary EF-hand calcium-binding protein of the brown planthopper Nilaparvata lugens functions as an effector for defense responses in rice

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