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Scientific Reports (18)
Experimental & Molecular Medicine (11)
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Showing 1–50 of 54 results

Advanced filters: Author: Hee Jung Um Clear advanced filters

Elliptic anisotropy measurement of the f₀(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A. Hayrapetyan
A. Tumasyan
A. Zhokin
ResearchOpen Access27 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Regulating Sirtuin 3-mediated mitochondrial dynamics through vanillic acid improves muscle atrophy in cancer-induced cachexia

Mechanistic insights into vanillic acid reveal its role in restoring muscle mass, reducing cytokines, and enhancing mitochondrial function via SIRT3 modulation, underscoring its therapeutic potential in muscle atrophy induced by cancer cachexia.

Gahee Song
Jinbong Park
Jae-Young Um
ResearchOpen Access09 Apr 2025
Communications Biology

Volume: 8, P: 1-15
Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6

The cytokine TGF-β signals through canonical, Smad-dependent, and non-canonical, Smad-independent pathways. Jung et al. show that Smad6, an inhibitor of canonical TGF-β signalling, also inhibits a non-canonical pathway by recruiting a deubiquitinase to TRAF6.

Su Myung Jung
Ji-Hyung Lee
Seok Hee Park
Research07 Oct 2013
Nature Communications

Volume: 4, P: 1-16
CD137 induces adhesion and cytokine production in human monocytic THP-1 cells

Jung-Won Choi
Hyeon-Woo Lee
KyuBum Kwack
ResearchOpen Access01 Apr 2005
Experimental & Molecular Medicine

Volume: 37, P: 78-85
Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells

Shin-Hae Kang
Ji-Hoon Song
Deok-Bae Park
ResearchOpen Access01 Apr 2003
Experimental & Molecular Medicine

Volume: 35, P: 83-90
Cysteine carboxyl O-methylation of human placental 23 kDa protein

Kyeong-Man Hong
Yong-Bock Choi
Moon-Kee Paik
ResearchOpen Access01 Mar 1999
Experimental & Molecular Medicine

Volume: 31, P: 30-35
Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells

Ji Hyun Kang
Youn Hee Park
Won Jung Lee
ResearchOpen Access01 Dec 2003
Experimental & Molecular Medicine

Volume: 35, P: 467-474
Roles of TNF-α and IgE in the late phase of contact hypersensitivity induced by trimellitic anhydride

Ok Hee Chai
Hern-Ku Lee
Chang Ho Song
ResearchOpen Access01 Oct 2005
Experimental & Molecular Medicine

Volume: 37, P: 408-417
Single-cell mapping of combinatorial target antigens for CAR switches using logic gates

CAR-T targets are identified using logic gates and single-cell expression data.

Joonha Kwon
Junho Kang
Jung Kyoon Choi
Research16 Feb 2023
Nature Biotechnology

Volume: 41, P: 1593-1605
Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice

Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of generating heat via uncoupled respiration. Here, Park et al. identify LETMD1 as a mitochondrial matrix protein enriched in brown adipose tissue (BAT) and reveal a crucial role for it in maintaining brown adipocyte mitochondrial OXPHOS and thermogenesis upon cold stimulus.

Anna Park
Kwang-eun Kim
Jae Myoung Suh
ResearchOpen Access23 Jun 2023
Nature Communications

Volume: 14, P: 1-14
Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27

Yun-Jee Seo
Mi-Hee Jeon
Jeong-Hwa Lee
ResearchOpen Access01 Dec 2005
Experimental & Molecular Medicine

Volume: 37, P: 624-630
Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers

Cellular defects in autophagy contribute to the development of fatty liver in obesity. Here, Park et al.reveal that hepatic autophagy is impaired by chronically elevated cytosolic calcium levels, and show that a clinically approved calcium channel blocker can improve metabolic parameters of obese mice.

Hwan-Woo Park
Haeli Park
Jun Hee Lee
Research05 Sept 2014
Nature Communications

Volume: 5, P: 1-12
ENOblock inhibits the pathology of diet-induced obesity

Haaglim Cho
Ji-Hyung Lee
Darren R. Williams
ResearchOpen Access24 Jan 2019
Scientific Reports

Volume: 9, P: 1-24
The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4

Jeong-Sun Seo
Hyonyong Chong
Hyen Sam Kang
ResearchOpen Access01 Jan 2005
Nature Biotechnology

Volume: 23, P: 63-68
Hydrogen diffusion and its electrical properties variation as a function of the IGZO stacking structure

Hee Yeon Noh
Woo-Geun Lee
Hyeon-Jun Lee
ResearchOpen Access17 Nov 2022
Scientific Reports

Volume: 12, P: 1-8
Transient pacing in pigs with complete heart block via myocardial injection of mRNA coding for the T-box transcription factor 18

Intramyocardial injection of synthetic mRNA coding for the embryonic T-box transcription factor 18 gene generates rate-adaptive cardiac pacing and limits innate and inflammatory immune responses, as shown in rodents and pigs.

David W. Wolfson
Nam Kyun Kim
Hee Cheol Cho
ResearchOpen Access02 May 2024
Nature Biomedical Engineering

Volume: 8, P: 1124-1141
Long-term outcomes according to additional treatments after endoscopic resection for rectal small neuroendocrine tumors

Jae Hwang Cha
Da Hyun Jung
Hyun Jung Lee
ResearchOpen Access20 Mar 2019
Scientific Reports

Volume: 9, P: 1-8
Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase

Hyun-Myung Choi
Yunu Jung
Jae-Young Um
ResearchOpen Access23 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
Sec13 induces genomic instability in U2OS cells

Choong-Ryoul Sihn
Eun-Jung Suh
Sang Hoon Kim
ResearchOpen Access01 Jun 2005
Experimental & Molecular Medicine

Volume: 37, P: 255-260
Association of DNA-dependent protein kinase with hypoxia inducible factor-1 and its implication in resistance to anticancer drugs in hypoxic tumor cells

Jee Hyun Um
Chi Dug Kang
Sun Hee Kim
ResearchOpen Access01 Jun 2004
Experimental & Molecular Medicine

Volume: 36, P: 233-242
Atrophy of brown adipocytes in the adult mouse causes transformation into white adipocyte-like cells

Dae Whan Kim
Beom Sue Kim
Chul Geun Kim
ResearchOpen Access01 Dec 2003
Experimental & Molecular Medicine

Volume: 35, P: 518-526
Interleukin-1β promotes the expression of monocyte chemoattractant protein-1 in human aorta smooth muscle cells via multiple signaling pathways

Jun Hee Lim
Hee Jung Um
Taeg Kyu Kwon
ResearchOpen Access30 Oct 2009
Experimental & Molecular Medicine

Volume: 41, P: 757-764
Observation of triple J/ψ meson production in proton-proton collisions

The CMS Collaboration reports the study of three simultaneous hard interactions between quarks and gluons in proton–proton collisions. This manifests through the concurrent production of three J/ψ mesons, which consist of a charm-quark–antiquark pair.

A. Tumasyan
W. Adam
W. Vetens
ResearchOpen Access19 Jan 2023
Nature Physics

Volume: 19, P: 338-350
Measurement of the Higgs boson width and evidence of its off-shell contributions to ZZ production

The CMS Collaboration reports evidence for off-shell Higgs boson contributions in the production of Z boson pairs, and measures the width of the Higgs boson, which is inversely related to its lifetime.

A. Tumasyan
W. Adam
W. Vetens
ResearchOpen Access20 Oct 2022
Nature Physics

Volume: 18, P: 1329-1334
PPIL4 is essential for brain angiogenesis and implicated in intracranial aneurysms in humans

Genomic analyses in individuals with index and familial intracranial aneurysms and experiments in vertebrate models identify pathogenic variants in the PPIL4 gene implicated in cerebral angiogenesis and cerebrovascular integrity, through the Wnt signaling pathway.

Tanyeri Barak
Emma Ristori
Murat Günel
Research09 Dec 2021
Nature Medicine

Volume: 27, P: 2165-2175
Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex

Arrays of bioresorbable, highly doped silicon electrodes with multiplexing capabilities are used as electrocorticography sensors to perform in vivo, reliable acute and chronic recordings for up to one month before dissolving in the body.

Ki Jun Yu
Duygu Kuzum
John A. Rogers
Research18 Apr 2016
Nature Materials

Volume: 15, P: 782-791
Fully implantable and battery-free wireless optoelectronic system for modulable cancer therapy and real-time monitoring

Kiho Kim
In Sik Min
Ki Jun Yu
ResearchOpen Access28 Aug 2023
npj Flexible Electronics

Volume: 7, P: 1-12
A portrait of the Higgs boson by the CMS experiment ten years after the discovery

The most up-to-date combination of results on the properties of the Higgs boson is reported, which indicate that its properties are consistent with the standard model predictions, within the precision achieved to date.

A. Tumasyan
W. Adam
A. Zhokin
ResearchOpen Access04 Jul 2022
Nature

Volume: 607, P: 60-68
Bisphenol A Affects on the Functional Properties and Proteome of Testicular Germ Cells and Spermatogonial Stem Cells in vitro Culture Model

Polash Chandra Karmakar
Hyun-Gu Kang
Buom-Yong Ryu
ResearchOpen Access19 Sept 2017
Scientific Reports

Volume: 7, P: 1-14
Bioactive secondary metabolites produced by an endophytic fungus Gaeumannomyces sp. JS0464 from a maritime halophyte Phragmites communis

Changyeol Lee
Soonok Kim
Sang Hee Shim
Research29 Mar 2017
The Journal of Antibiotics

Volume: 70, P: 737-742
Acute exposure to silica nanoparticles aggravate airway inflammation: different effects according to surface characteristics

Hye Jung Park
Jung-Ho Sohn
Jae-Hyun Lee
ResearchOpen Access17 Jul 2015
Experimental & Molecular Medicine

Volume: 47, P: e173
Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder

Il Bin Kim
Taeyeop Lee
Jeong Ho Lee
Research15 Jul 2022
Molecular Psychiatry

Volume: 27, P: 4680-4694
Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies

Hyun Mi Kang
Jung Hwa Lim
Cho-Rok Jung
ResearchOpen Access26 Nov 2019
Scientific Reports

Volume: 9, P: 1-17
Effectiveness of a collagen matrix seal and xenograft in alveolar ridge preservation: an experimental study in dogs

Hee-seung Han
Jung-Tae Lee
Sungtae Kim
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-10
Preclinical assessment of the VEGFR inhibitor axitinib as a therapeutic agent for epithelial ovarian cancer

E Sun Paik
Tae-Hyun Kim
Jeong-Won Lee
ResearchOpen Access17 Mar 2020
Scientific Reports

Volume: 10, P: 1-9
RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-κB-mediated ERK reactivation

Jung Hee Cho
Yeon-Mi You
Kyung Chan Park
ResearchOpen Access22 May 2018
Cell Death & Disease

Volume: 9, P: 1-13
JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway

Min Seong Kim
Hye In Cho
Yeun Kyu Jang
ResearchOpen Access26 Apr 2018
Scientific Reports

Volume: 8, P: 1-12
Rubi Fructus (Rubus coreanus) activates the expression of thermogenic genes in vivo and in vitro

M-Y Jeong
H-L Kim
J-Y Um
Research11 Aug 2014
International Journal of Obesity

Volume: 39, P: 456-464
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

Swapan Nath, Sang-Cheol Bae and colleagues report the results of a large-scale association study of systemic lupus erythematosus in individuals of Asian ancestry. They identify several new susceptibility loci and find enrichment for signals near genes implicated in B cell and T cell function.

Celi Sun
Julio E Molineros
Swapan K Nath
Research25 Jan 2016
Nature Genetics

Volume: 48, P: 323-330
Coiled-coil domain containing 3 suppresses breast cancer growth by protecting p53 from proteasome-mediated degradation

Caiyue Li
Hyemin Lee
Hua Lu
Research17 Nov 2022
Oncogene

Volume: 42, P: 154-164
TM4SF5-mediated CD44v8-10 splicing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis

Ji Eon Kim
Hye-Jin Kim
Jung Weon Lee
ResearchOpen Access09 Sept 2019
Cell Death & Disease

Volume: 10, P: 1-16
Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo

Eunju Leem
Hyung-Jun Kim
Sang Ryong Kim
ResearchOpen Access18 Apr 2018
Cell Death & Disease

Volume: 9, P: 1-15
The role of dexamethasone in mediating the contradictory effects of Wnt antagonists SFRP2 and SFRP3 on human hair follicle growth

Ons Ben Hamida
Moon Kyu Kim
Mi Hee Kwack
ResearchOpen Access02 Oct 2023
Scientific Reports

Volume: 13, P: 1-11
ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes

Haaglim Cho
JungIn Um
Darren R. Williams
ResearchOpen Access08 Mar 2017
Scientific Reports

Volume: 7, P: 1-16
Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes

Ji-Eun Bae
Hyunjung Choi
Dong-Hyung Cho
ResearchOpen Access08 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Screening ginseng saponins in progenitor cells identifies 20(R)-ginsenoside Rh₂ as an enhancer of skeletal and cardiac muscle regeneration

Ah Ra Kim
Seon-Wook Kim
Darren R. Williams
ResearchOpen Access18 Mar 2020
Scientific Reports

Volume: 10, P: 1-16
Heat-killed Lactobacillus casei confers broad protection against influenza A virus primary infection and develops heterosubtypic immunity against future secondary infection

Yu-Jin Jung
Young-Tae Lee
Sang-Moo Kang
ResearchOpen Access12 Dec 2017
Scientific Reports

Volume: 7, P: 1-12
Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment

Yong Sook Kim
Hye-yun Jeong
Youngkeun Ahn
ResearchOpen Access11 Aug 2016
Scientific Reports

Volume: 6, P: 1-13
Exploration of sub-bandgap states in 2D halide perovskite single-crystal photodetector

Eunyoung Choi
Yurou Zhang
Jae Sung Yun
ResearchOpen Access23 Jun 2022
npj 2D Materials and Applications

Volume: 6, P: 1-10
Impact of Amyloid Burden on Regional Functional Synchronization in the Cognitively Normal Older Adults

Dong Woo Kang
Woo Hee Choi
Hyun Kook Lim
ResearchOpen Access31 Oct 2017
Scientific Reports

Volume: 7, P: 1-9

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