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Showing 51–91 of 91 results

Advanced filters: Author: Hideki Abe Clear advanced filters

Genome sequencing and analysis of Aspergillus oryzae

Masayuki Machida
Kiyoshi Asai
Hisashi Kikuchi
Research22 Dec 2005
Nature

Volume: 438, P: 1157-1161
The genome of the mesopolyploid crop species Brassica rapa

The Brassica rapa Genome Sequencing Project Consortium reports the draft genome of the B. rapa accession Chiifu-401-42, an inbred Chinese cabbage line. The B. rapa genome should provide a useful reference genome for the Brassica species, which include many important oil and vegetable crops.

Xiaowu Wang
Hanzhong Wang
Zhonghua Zhang
Research28 Aug 2011
Nature Genetics

Volume: 43, P: 1035-1039
Patient characteristics modify the association between changes in mineral metabolism parameters and mortality in a nationwide hemodialysis cohort study

Shunsuke Goto
Takayuki Hamano
Hideki Fujii
ResearchOpen Access08 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Crystal Growth of Isotactic Poly(butene-1) in the Melt. I. Kinetic Roughening

Motoi Yamashita
Hideki Miyaji
Kunihide Izumi
Research15 Mar 2004
Polymer Journal

Volume: 36, P: 226-237
cAMP-Response Element-Binding Protein Mediates Tumor Necrosis Factor-α-Induced Vascular Cell Adhesion Molecule-1 Expression in Endothelial Cells

Hiroki Ono
Toshihiro Ichiki
Kenji Sunagawa
Research01 Jan 2006
Hypertension Research

Volume: 29, P: 39-47
Determination of Sequence Distribution of Substituted and Unsubstituted Glucopyranose Units in Water-Soluble Cellulose Acetate Chain as Revealed by Enzymatic Degradation

Hideki Iijima
Keisuke Kowsaka
Kenji Kamide
Research01 Oct 1992
Polymer Journal

Volume: 24, P: 1077-1097
Thermodynamics of Formation of Porous Polymeric Membrane by Phase Separation Method III. Pore Formation by Contacting Secondary Particles: Theory and Its Comparison with Experiments

Hideki Iijima
Shigenobu Matsuda
Kenji Kamide
Research01 Apr 1994
Polymer Journal

Volume: 26, P: 439-463
Dehydration of Water/Ethanol Mixtures by Pervaporation Using Modified Poly(vinyl alcohol) Membrane

Shinsuke Takegami
Hideki Yamada
Shoji Tsujii
Research01 Nov 1992
Polymer Journal

Volume: 24, P: 1239-1250
Inhibition of Balloon Injury–Induced Neointimal Formation by Olmesartan and Pravastatin in Rats with Insulin Resistance

Ming Chen
Toshihiro Ichiki
Kenji Sunagawa
Research01 Oct 2007
Hypertension Research

Volume: 30, P: 971-978
Inactivation of a c-Myb/estrogen receptor fusion protein in transformed primary cells leads to granulocyte/macrophage differentiation and down regulation of c-kit but not c-myc or cdc2

Annette Hogg
Sabine Schirm
Thomas J Gonda
Research11 Dec 1997
Oncogene

Volume: 15, P: 2885-2898
dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

Soichi Ogishima
Satoshi Nagaie
Masayuki Yamamoto
ResearchOpen Access10 Dec 2021
Human Genome Variation

Volume: 8, P: 1-8
Four-dimensional anatomical spinal reconstruction using pre-bent rods in thoracic adolescent idiopathic scoliosis

Akira Fukushima
Takashi Ohnishi
Hideki Sudo
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-9
Sea ice records over more than a century at an observatory facing the Okhotsk coast of Hokkaido, Japan

Takahiro Toyoda
Kento Tsukagawa
Masao Ishii
ResearchOpen Access13 Jun 2025
Scientific Data

Volume: 12, P: 1-10
Validation of the obesity paradox by body mass index and waist circumference in patients undergoing percutaneous coronary intervention

Yuichiro Shirahama
Noriaki Tabata
Junichi Matsubara
Research28 Jul 2022
International Journal of Obesity

Volume: 46, P: 1840-1848
Blood perfusion with polymyxin B immobilized columns in patients with COVID-19 requiring oxygen therapy

Daisuke Katagiri
Akinari Tsukada
Haruhito Sugiyama
ResearchOpen Access31 May 2024
Scientific Reports

Volume: 14, P: 1-10
Thermal properties of poly(3-hydroxy-2-methylbutyrate-co-3-hydroxybutyrate) copolymers with narrow comonomer-unit compositional distributions

Polyhydroxyalkanoate copolymers of (2R,3R)-3-hydroxy-2-methylbutyrate and (R)-3-hydroxybutyrate [P(3H2MB-co-3HB)] with various comonomer compositions were biosynthesized using recombinant Escherichia coli. Furthermore, solvent fractionation of P(3H2MB-co-3HB) was performed to obtain copolymers with narrow comonomer-unit compositional distributions. The melting temperature (T_m) of P(3H2MB-co-3HB) as a function of the comonomer content indicated isodimorphism of the copolymer. The fast crystallization behavior of P(3H2MB) was maintained even when it was copolymerized with 3HB. The P(80 mol% 3H2MB-co-3HB) copolymer, with a T_m close to that of P(3HB), exhibited faster crystallization behavior than the P(3HB) homopolymer.

Sho Furutate
Hideki Abe
Takeharu Tsuge
Research12 Aug 2021
Polymer Journal

Volume: 53, P: 1451-1457
Automated noninvasive detection of idiopathic scoliosis in children and adolescents: A principle validation study

Hideki Sudo
Terufumi Kokabu
Satoshi Kanai
ResearchOpen Access07 Dec 2018
Scientific Reports

Volume: 8, P: 1-10
A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation

Nawin Chanthra
Tomoyuki Abe
Hideki Uosaki
ResearchOpen Access06 Mar 2020
Scientific Reports

Volume: 10, P: 1-13
Increased Expression of gp91phox Homologues of NAD(P)H Oxidase in the Aortic Media during Chronic Hypertension: Involvement of the Renin-Angiotensin System

Takashi Akasaki
Yusuke Ohya
Mitsuo Iida
Research01 Oct 2006
Hypertension Research

Volume: 29, P: 813-820
Deep learning driven de novo drug design based on gastric proton pump structures

Deep generative models are used to develop gastric proton pump blockers with novel chemical skeletons and strong inhibitory potency.

Kazuhiro Abe
Mami Ozako
Atsushi Yoshimori
ResearchOpen Access19 Sept 2023
Communications Biology

Volume: 6, P: 1-14
PAM-flexible Cas9-mediated base editing of a hemophilia B mutation in induced pluripotent stem cells

Hiramoto et al. develop a base-editing approach using SpCas9-NG, an engineered Cas9 with broad PAM flexibility, to correct a causative mutation in hemophilia B. Their approach is used to repair the point mutation in patient-derived iPSCs and restore coagulation factor IX expression in HEK293 cells and knock-in mice.

Takafumi Hiramoto
Yuji Kashiwakura
Tsukasa Ohmori
ResearchOpen Access19 Apr 2023
Communications Medicine

Volume: 3, P: 1-12
Long COVID occurrence in COVID-19 survivors

Aya Sugiyama
Kei Miwata
Junko Tanaka
ResearchOpen Access11 Apr 2022
Scientific Reports

Volume: 12, P: 1-11
An almost nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, as an odorant for the grass puffer

Yoshihisa Noguchi
Takehisa Suzuki
Hideki Abe
ResearchOpen Access05 Sept 2022
Scientific Reports

Volume: 12, P: 1-10
Optimal value of CA19-9 determined by KRAS-mutated circulating tumor DNA contributes to the prediction of prognosis in pancreatic cancer patients

Fumiaki Watanabe
Koichi Suzuki
Toshiki Rikiyama
ResearchOpen Access21 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
Superior thermal stability and fast crystallization behavior of a novel, biodegradable α-methylated bacterial polyester

The biosynthesis and characterization of a new biodegradable plastic, poly(3-hydroxy-2-methylbutyrate) [P(3H2MB)], which is a member of the bacterial polyhydroxyalkanoate (PHA) family whose members include an α-methylated monomer unit, were investigated. Biosynthesized P(3H2MB) exhibited the highest melting temperature (197 °C) among the biosynthesized PHAs and improved thermal resistance. It also exhibited improved crystallization behavior and mechanical flexibility nearly equal to those of isotactic polypropylene (iPP). The superior physical properties of P(3H2MB) have the potential to open new avenues for the production of high-performance biodegradable plastics for replacing petroleum-based bulk commodity plastics.

Sho Furutate
Junichi Kamoi
Takeharu Tsuge
ResearchOpen Access02 Apr 2021
NPG Asia Materials

Volume: 13, P: 1-11
Unique acrylic resins with aromatic side chains by homopolymerization of cinnamic monomers

Cinnamic acid and related monomers are challenging to polymerise but offer interesting features combining structural elements of both acrylates and styrenes. Here homopolymers of cinnamic monomers are obtained by group transfer polymerisation under mild conditions.

Motosuke Imada
Yasumasa Takenaka
Hideki Abe
ResearchOpen Access16 Sept 2019
Communications Chemistry

Volume: 2, P: 1-9
Oligomeric states of microbial rhodopsins determined by high-speed atomic force microscopy and circular dichroic spectroscopy

Mikihiro Shibata
Keiichi Inoue
Takayuki Uchihashi
ResearchOpen Access29 May 2018
Scientific Reports

Volume: 8, P: 1-11
Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils

Keigo Ueno
Makoto Urai
Yuki Kinjo
ResearchOpen Access27 Nov 2018
Scientific Reports

Volume: 8, P: 1-13
Unique defect structure and advantageous vortex pinning properties in superconducting CaKFe₄As₄

Shigeyuki Ishida
Akira Iyo
Michael Eisterer
ResearchOpen Access03 Jun 2019
npj Quantum Materials

Volume: 4, P: 1-7
CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene

Michiko Hirose
Ayumi Hasegawa
Atsuo Ogura
ResearchOpen Access14 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
Melting Temperature Mapping Method: A Novel Method for Rapid Identification of Unknown Pathogenic Microorganisms within Three Hours of Sample Collection

Hideki Niimi
Tomohiro Ueno
Isao Kitajima
ResearchOpen Access28 Jul 2015
Scientific Reports

Volume: 5, P: 1-13
OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

Daisuke Oikawa
Min Gi
Fuminori Tokunaga
ResearchOpen Access08 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-13
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17
Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts

Kumi Ubukawa
Tatsufumi Goto
Naoto Takahashi
ResearchOpen Access16 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Initial report of γ-aminobutyric acidergic locomotion regulatory system and its 3-mercaptopropionic acid-sensitivity in metamorphic juvenile of sea urchin, Hemicentrotus pulcherrimus

Hideki Katow
Hiromi Yoshida
Masato Kiyomoto
ResearchOpen Access21 Jan 2020
Scientific Reports

Volume: 10, P: 1-13
Understanding Colour Tuning Rules and Predicting Absorption Wavelengths of Microbial Rhodopsins by Data-Driven Machine-Learning Approach

Masayuki Karasuyama
Keiichi Inoue
Ichiro Takeuchi
ResearchOpen Access22 Oct 2018
Scientific Reports

Volume: 8, P: 1-11
Temperature elevation in epileptogenic foci exacerbates epileptic discharge through TRPV4 activation

The authors reveal that TRPV4, a thermosensitive ion channel, is constitutively active in the brain. They found that local brain temperature is increased at epileptogenic foci, and that hyperthermia lead TRPV4 over-activation and hyper-neuronal activities. Notably, brain cooling treatment drastically suppresses epileptic discharges dependent on the inactivation of TRPV4.

Koji Shibasaki
Katsuya Yamada
Yasuki Ishizaki
Research22 Oct 2019
Laboratory Investigation

Volume: 100, P: 274-284
Improving the marine biodegradability of poly(alkylene succinate)-based copolymers

We report the syntheses of novel marine biodegradable poly(ethylene succinate) (PES)- and poly(butylene succinate) (PBS)-based copolymers containing different dicarboxylic acid (DCA) units with various carbon numbers and different feed ratios. Specifically, the copolymers with longer-chain DCA units, even at low contents, exhibited marine biodegradability. The thermomechanical properties also varied with the DCA contents. These results indicated that the thermomechanical properties and the marine biodegradability of the PES- and PBS-based copolymers were regulated by controlling their structures and DCA contents.

Sumito Kumagai
Senri Hayashi
Yasumasa Takenaka
ResearchOpen Access17 Jan 2024
Polymer Journal

Volume: 56, P: 419-429
Copolymers incorporated with β-substituted acrylate synthesized by organo-catalyzed group-transfer polymerization

The copolymerization of β-substituted acrylates (i.e., crotonates and a cinnamate) using an organo-catalyzed group-transfer polymerization system with N-(tert-butyldimethylsilyl)bis(trifluoromethanesulfonyl)imide (Tf₂NSi^tBuMe₂) and 1-methoxy-1-(tert-butyldimethylsiloxy)-2-methyl-1-propene (^tBuMe2SKA) was investigated. The tert-butyldimethylsilyl moiety served as an effective means for suppressing the termination reactions of the GTP system. One-stage and two-stage copolymerization strategies employing different monomer feed methods were evaluated and gave random and block copolymers, respectively. The glass-transition temperatures of the prepared copolymers varied significantly depending on the comonomer used during the synthesis.

Motosuke Imada
Yasumasa Takenaka
Hideki Abe
ResearchOpen Access19 May 2021
Polymer Journal

Volume: 53, P: 989-999
Fractionation and thermal characteristics of biosynthesized polyhydoxyalkanoates bearing aromatic groups as side chains

Two polyhydroxyalkanoate copolymers, poly(3-hydroxybutyrate-co-3-hydroxy-3-phenylpropioate) [P(3HB-co-3H3PhP)] and poly(3-hydroxybutyrate-co-3-hydroxy-4-phenylbutyrate) [P(3HB-co-3H4PhB)] were biosynthesized. The as-biosynthesized polymers were fractionated into several fractions with narrow comonomer compositional distribution using a chloroform/n-hexane mixed solvent. Using these fractions, the effects of aromatic comonomers on the thermal properties were investigated.

Shoji Mizuno
Ayaka Hiroe
Takeharu Tsuge
Research12 Apr 2017
Polymer Journal

Volume: 49, P: 557-565
Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer

Tetsuji Nakagawachi
Hidenobu Soejima
Tsunehiro Mukai
Research04 Dec 2003
Oncogene

Volume: 22, P: 8835-8844

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