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Showing 1–50 of 194 results

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Maternal Antenatal Magnesium Does Not Prevent Retinopathy of Prematurity (ROP) or Severe Head Ultrasound (HUS) Abnormalities in Very Low Birth Weight Premature Infants-Severe HUS Abnormalities and ROP Are Significantly Related

Stephen Baumgart
Terri L Saunders
Alan R Spitzer
Research01 Apr 1999
Pediatric Research

Volume: 45, P: 185
Azithromycin and decolonization after HUS

An observational study associates azithromycin use with accelerated stool decolonization in patients infected with Shiga toxin-producing Escherichia coli O104:H4. Even if this association is causal, however, the value of late-in-illness treatment is not established and the results provide no support for early-in-illness treatment of Shiga toxin-producing E. coli infections.

Michael E. Seifert
Phillip I. Tarr
News & Views01 May 2012
Nature Reviews Nephrology

Volume: 8, P: 317-318
Atypical HUS: current diagnostic and therapeutic approaches

The management of patients with hemolytic uremic syndrome is challenging, and strategies for accurate diagnosis and effective treatment are needed. Intensive research over the past several years has revealed dysregulation of the complement system to be the main underlying cause of the syndrome, making this system the target of promising novel diagnostic and treatment strategies.

Alejandra Rosales
Magdalena Riedl
Lothar B. Zimmerhackl
News & Views01 Sept 2010
Nature Reviews Nephrology

Volume: 6, P: 504-506
PROTRACTED DEFICIENCY OF α-TOCOPHEROL (α- TOC) AND ESSENTIAL FATTY ACIDS (EFA) IN ENTEROPATHIC HEMOLYTIC-UREMIC SYNDROME (e+HUS)

O Amon
C Hübner
D E Müller-Wiefel
Research01 Nov 1992
Pediatric Research

Volume: 32, P: 625
Leveraging glucan-induced trained immunity for the epigenetic and metabolic rewiring of macrophages to enhance colorectal cancer vaccine response

Beta-glucan is an inducer of trained immunity, an epigenetic and metabolic reprogramming of the innate immune cells conferring immunological memory. Here the authors show that glucan-induced trained immunity enhances response to a cancer vaccine platform in colorectal cancer models, by inducing epigenetic and metabolic rewiring of macrophages that promotes an NK-cDC1 axis boosting anti-tumor immunity.

Firas Hamdan
Sara Gandolfi
Vincenzo Cerullo
ResearchOpen Access28 Jan 2026
Nature Communications

Volume: 17, P: 1-20
Von Willebrand Factor and Von Willebrand Factor-Cleaving Metalloprotease Activity in Escherichia coli O157:H7-Associated Hemolytic Uremic Syndrome

Han-Mou Tsai
Wayne L Chandler
Phillip I Tarr
Research01 May 2001
Pediatric Research

Volume: 49, P: 653-659
Complex genetic effects linked to plasma protein abundance in the UK Biobank

The authors present a deep learning approach to uncover complex genetic effects on circulating protein levels. They reveal new interactions and dominance patterns using UK Biobank proteomics data.

Arnor I. Sigurdsson
Justus F. Gräf
Simon Rasmussen
ResearchOpen Access14 Dec 2025
Nature Communications

Volume: 17, P: 1-15
The Functional State of Neutrophils Correlates With the Severity of Renal Dysfunction in Children With Hemolytic Uremic Syndrome

Gabriela C Fernandez
Sonia A Gomez
Marina S Palermo
Research01 Jan 2007
Pediatric Research

Volume: 61, P: 123-128
Noninvasive neurocritical care monitoring for neonates on extracorporeal membrane oxygenation: where do we stand?

Zeenia C. Billimoria
Natalie E. Rintoul
Robert J. DiGeronimo
Research04 Aug 2020
Journal of Perinatology

Volume: 41, P: 830-835
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling

Genome-wide association meta-analysis identifies 58 independent risk loci for major anxiety disorders among individuals of European ancestry and implicates GABAergic signaling as a potential mechanism underlying genetic risk for these disorders.

Nora I. Strom
Brad Verhulst
John M. Hettema
ResearchOpen Access03 Feb 2026
Nature Genetics

Volume: 58, P: 275-288
Severe thrombotic microangiopathy: an infrequent complication of bone marrow transplantation

P Iacopino
G Pucci
A Bacigalupo
Research23 Jul 1999
Bone Marrow Transplantation

Volume: 24, P: 47-51
Whole-genome resequencing of wild and domestic sheep identifies genes associated with morphological and agronomic traits

Genetic resources for livestock are valuable for understanding their demography and past selection, and may inform future breeding programs and agricultural improvement. Here, the authors present deep resequencing of 248 wild and domestic sheep, with associated data and analysis.

Xin Li
Ji Yang
Meng-Hua Li
ResearchOpen Access04 Jun 2020
Nature Communications

Volume: 11, P: 1-16
999 Dialysis in Acute Renal Failure of Hemolytic Uremic Syndrom in Children

I Oprescu
O C Limoncu
Research01 Nov 2010
Pediatric Research

Volume: 68, P: 497
Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence

PurR acts as transcriptional repressor of purine biosynthesis genes in some bacterial species. Here, the authors show that purR mutations can arise in Staphylococcus aureus upon exposure to stress, leading to upregulation of fibronectin-binding proteins and increased virulence.

Mariya I. Goncheva
Ronald S. Flannagan
David E. Heinrichs
ResearchOpen Access15 Feb 2019
Nature Communications

Volume: 10, P: 1-14
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

A genome-wide meta-analysis of data from six US and European cohorts involving 1.3 million individuals identifies 243 genetic variants associated with risk and pathophysiology of depression, which is used to develop polygenic risk scores for the prediction of depression recurrence and comorbid psychiatric disorders.

Thomas D. Als
Mitja I. Kurki
Anders D. Børglum
Research18 Jul 2023
Nature Medicine

Volume: 29, P: 1832-1844
Azithromycin decolonization of STEC—a new risk emerges

Michael E. Seifert
Phillip I. Tarr
Correspondence05 Jun 2012
Nature Reviews Nephrology

Volume: 8, P: 429
Global distribution of epidemic-related Shiga toxin 2 encoding phages among enteroaggregative Escherichia coli

Keiko Kimata
Kenichi Lee
Sunao Iyoda
ResearchOpen Access16 Jul 2020
Scientific Reports

Volume: 10, P: 1-8
FinnGen provides genetic insights from a well-phenotyped isolated population

Genome-wide association studies of individuals from an isolated population (data from the Finnish biobank study FinnGen) and consequent meta-analyses facilitate the identification of previously unknown coding variant associations for both rare and common diseases.

Mitja I. Kurki
Juha Karjalainen
Aarno Palotie
ResearchOpen Access18 Jan 2023
Nature

Volume: 613, P: 508-518
Risk factors and associated diseases among preterm infants with isolated lenticulostriate vasculopathy

A Maayan-Metzger
L Leibovitch
T Strauss
Research21 Apr 2016
Journal of Perinatology

Volume: 36, P: 775-778
Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events

In this study, the authors showed how common genetic factors in the form of epilepsy polygenic risk scores influence epilepsy risk across lifetime and after unspecified seizure events. This could eventually help epilepsy diagnosis.

Henrike O. Heyne
Fanny-Dhelia Pajuste
Mark J. Daly
ResearchOpen Access25 Jul 2024
Nature Communications

Volume: 15, P: 1-11
Diffuse correlation spectroscopy blood flow monitoring for intraventricular hemorrhage vulnerability in extremely low gestational age newborns

John Sunwoo
Alexander I. Zavriyev
Mohamed El-Dib
ResearchOpen Access27 Jul 2022
Scientific Reports

Volume: 12, P: 1-12
Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Narcolepsy has genetic and environmental risk factors, but the specific genetic risk loci and interaction with environmental triggers are not well understood. Here, the authors identify genetic loci for narcolepsy, suggesting infection as a trigger and dendritic and helper T cell involvement.

Hanna M. Ollila
Eilon Sharon
Emmanuel J. Mignot
ResearchOpen Access15 May 2023
Nature Communications

Volume: 14, P: 1-13
Body composition and lung cancer-associated cachexia in TRACERx

Results of the TRACERx study shed new light into the association between body composition and body weight with survival in individuals with non-small cell lung cancer, and delineate potential biological processes and mediators contributing to the development of cancer-associated cachexia.

Othman Al-Sawaf
Jakob Weiss
Charles Swanton
Research12 Apr 2023
Nature Medicine

Volume: 29, P: 846-858
THE ROLE OF ALDOSTERONE IN RENAL ELECTROLYTE TRANSPORT DURING DEVELOPMENT

Yuhei Ito
David I Goldsmith
Adrian Spitzer
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 370
Na REABSORPTION AND K SECRETION IN THE DISTAL TUBULE OF NEWBORN DOGS

L I Kleinman
R O Banks
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 553
EFFECT OF POLYCYTHEMIA ON RENAL FUNCTION IN NEWBORN DOGS

Uma R Kotagal
Theresa Disney
Leonard I Kleinman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 553
MATURATION OF RENAL ENZYMES IN NEWBORN RATS

L I Kleinman
H Wald
J W Czazkes
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 553
Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing

Fang et al. generate the first genome-wide, strand-specific, single base–pair resolution map of m6A modifications in Escherichia coli.

Gang Fang
Diana Munera
Eric E Schadt
Research08 Nov 2012
Nature Biotechnology

Volume: 30, P: 1232-1239
997 Pseudohypoaldosteronism Type 1, Renal Form- a Case Report

V P Despotova
M Kalajdgieva
K Grozdeva
Research01 Nov 2010
Pediatric Research

Volume: 68, P: 496-497
998 Percutaneous Transluminal Angioplasty in a Child with Renal Artery Fibromuscular Dysplasia

I Petrov
V Chervenkoff
M Lilova
Research01 Nov 2010
Pediatric Research

Volume: 68, P: 497
Priority European strategies for sustainable access to high-quality genetic counselling in cancer: A Delphi study

J. Matt McCrary
Els Van Valckenborgh
Anke Katharina Bergmann
ResearchOpen Access13 Feb 2026
European Journal of Human Genetics

P: 1-11
Pattern Formation in Aggregations of Entities of Varied Size and Shapes as Seen in Mosaics

RICHARD E. M. MOORE
Research08 Jan 1966
Nature

Volume: 209, P: 128-132
Detection of Escherichia coli O157:H7 in imported meat products from Saudi Arabian ports in 2017

Meshari Ahmed Alhadlaq
Mohammed I. Mujallad
Sulaiman M. I. Alajel
ResearchOpen Access14 Mar 2023
Scientific Reports

Volume: 13, P: 1-6
Genome-wide analyses identify 25 infertility loci and relationships with reproductive traits across the allele frequency spectrum

Genome-wide analyses identify variants associated with infertility and reproductive hormone levels but find limited polygenic overlap between reproductive hormone levels and infertility at the population level.

Samvida S. Venkatesh
Laura B. L. Wittemans
Cecilia M. Lindgren
ResearchOpen Access14 Apr 2025
Nature Genetics

Volume: 57, P: 1107-1118
Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes

Genome-wide association analyses identify 13 loci associated with gestational diabetes, showing partial overlap with type 2 diabetes risk loci but also distinct genetic architecture predominantly influencing pregnancy-related mechanisms.

Amanda Elliott
Raymond K. Walters
Elisabeth Widén
ResearchOpen Access05 Jan 2024
Nature Genetics

Volume: 56, P: 377-382
The renaissance of complement therapeutics

Complement activation has important physiological and pathological implications for kidney-related and other diseases. Here, the authors discuss the state of the art of complement therapeutics, including the targets, candidate drugs, insights from clinical trials and evolving challenges for the field.

Daniel Ricklin
Dimitrios C. Mastellos
John D. Lambris
Reviews04 Dec 2017
Nature Reviews Nephrology

Volume: 14, P: 26-47
Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage

Petri Paakkari
Satu I. Inkinen
Juuso T. J. Honkanen
ResearchOpen Access02 Dec 2024
Scientific Reports

Volume: 14, P: 1-14
Identification of a New Virulent Clade in Enterohemorrhagic Escherichia coli O26:H11/H- Sequence Type 29

Nozomi Ishijima
Ken-ichi Lee
Sunao Iyoda
ResearchOpen Access23 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
Missense variants in FRS3 affect body mass index in populations of diverse ancestries

Understanding the underlying pathophysiology of obesity can help prevent this condition. Here, the authors perform a GWAS of BMI in diverse ancestries, finding four missense variants in FRS3 that affect BMI.

Andrea B. Jonsdottir
Gardar Sveinbjornsson
Kari Stefansson
ResearchOpen Access25 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development

Cell metabolism has emerged as a major factor implicated in human brain evolution. Here, the authors show that an ape-specific enzyme enhances the ability of a human-specific enzyme to increase glutaminolysis and therefore expand the size of the human neocortex.

Lei Xing
Vasiliki Gkini
Takashi Namba
ResearchOpen Access24 Apr 2024
Nature Communications

Volume: 15, P: 1-13
AZOTEMIA, HEMOLYTIC ANEMIA, WITH MINIMAL RENAL MICROANGIOPATHY IN A PATIENT WITH COMBINED IMMUNODEFICIENCY (CID), AND RHEOVIRUS (RV) INFECTION

I Bangash
E John
Research01 Aug 1980
Pediatric Research

Volume: 14, P: 985
Genetic associations of protein-coding variants in human disease

A meta-analysis combining whole-exome sequencing data from UK Biobank participants and imputed genotypes from FinnGen participants enables identification of genetic associations with human disease in the rare and low-frequency allelic spectrum

Benjamin B. Sun
Mitja I. Kurki
Heiko Runz
ResearchOpen Access23 Feb 2022
Nature

Volume: 603, P: 95-102
Investigating the effects of TMS-related somatosensory inputs on TMS-evoked potentials provides evidence against significant interaction

Pedro C. Gordon
Johanna Metsomaa
Ulf Ziemann
ResearchOpen Access30 Jan 2026
Scientific Reports

Volume: 16, P: 1-18
Liquid Chromatographic Separation of Mixtures of Polymers and Mineral Oil

P. I. BREWER
Research10 Dec 1960
Nature

Volume: 188, P: 934-935
Specific Diagnosis of Typhus Fever by Rickettsial Agglutination

I. J. KLIGLER
E. OLEJNIK
Research27 Nov 1943
Nature

Volume: 152, P: 627-628
Radiometric Estimation of Unsaturated Fatty Acids on Chromatograms

A. Z. BUDZYŃSKI
Z. J. ZUBRZYCKI
I. G. CAMPBELL
Research19 Jul 1958
Nature

Volume: 182, P: 178-179
Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank

MILTON uses phenotype information in the UK Biobank to identify clinical biomarkers and other quantitative traits that characterize diseases. It then constructs augmented cohorts by predicting undiagnosed individuals, improving power to discover gene–disease relationships.

Manik Garg
Marcin Karpinski
Dimitrios Vitsios
ResearchOpen Access11 Sept 2024
Nature Genetics

Volume: 56, P: 1821-1831
Association analyses identify 31 new risk loci for colorectal cancer susceptibility

In colorectal cancer (CRC), finding loci associated with risk may give insight into disease aetiology. Here, the authors report a genome-wide association analysis in Europeans of 34,627 CRC cases and 71,379 controls, and find 31 new risk loci and 17 new risk SNPs at previously reported loci.

Philip J. Law
Maria Timofeeva
Malcolm G. Dunlop
ResearchOpen Access14 May 2019
Nature Communications

Volume: 10, P: 1-15
APOLIPOPROTEIN B (APO B) GENE IN CONGENITAL DISORDERS OF FAT ABSORPTION

M Pessah
M E Bouma
J Schmitz
Research01 Sept 1989
Pediatric Research

Volume: 26, P: 281
Mathematical Model of Clonal Selection and Antibody Production

GEORGE I. BELL
Research21 Nov 1970
Nature

Volume: 228, P: 739-744

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