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Showing 51–100 of 1514 results

Advanced filters: Author: J P McCarthy Clear advanced filters

Diminished immune cell adhesion in hypoimmune ICAM-1 knockout human pluripotent stem cells

Hypoimmune gene editing in human pluripotent stem cells (hPSCs) provides a promising platform for cellular therapies. Here, the authors report that CRISPR mediated deletion of ICAM-1 in hPSC-derived grafts reduces immune cell adhesion, dampens T cell activation, and protects against immune rejection.

Sayandeep Saha
W. John Haynes
Matthew E. Brown
ResearchOpen Access12 Aug 2025
Nature Communications

Volume: 16, P: 1-16
Activation of Kidney Mitochondrial Glutaminase by Inorganic Phosphate and Organic Acids

D. J. O'DONOVAN
W. D. LOTSPEICH
Research26 Nov 1966
Nature

Volume: 212, P: 930-932
A high-redshift IRAS galaxy with huge luminosity―hidden quasar or protogalaxy?

M. Rowan-Robinson
T. Broadhurst
J. J. Condon
Research27 Jun 1991
Nature

Volume: 351, P: 719-721
Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses

S. SPIEGELMAN
A. BURNY
K. WATSON
Research08 Aug 1970
Nature

Volume: 227, P: 563-567
Unique and repetitive sequences in multiple genes for feather keratin

David J. Kemp
Research01 Apr 1975
Nature

Volume: 254, P: 573-577
The power of genetic diversity in genome-wide association studies of lipids

A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Research09 Dec 2021
Nature

Volume: 600, P: 675-679
Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite

P. H. Reitsma
P. G. Rothberg
A. J. Kahn
Research01 Dec 1983
Nature

Volume: 306, P: 492-494
Novel treatment for joint inflammation

J. T. DINGLE
J. L. GORDON
J. S. LOWE
Research01 Jan 1978
Nature

Volume: 271, P: 372-373
Proton Magnetic Resonance, Magnetic Susceptibility and Mössbauer Studies of Clostridium pasteurianum Rubredoxin

W. D. PHILLIPS
M. POE
W. LOVENBERG
Research08 Aug 1970
Nature

Volume: 227, P: 574-577
Separation of membrane currents using a Paramecium mutant

Donata Oertel
Stanley J. Schein
Ching Kung
Research14 Jul 1977
Nature

Volume: 268, P: 120-124
Integrated community-based HIV and sexual and reproductive health services for youth: a cluster-randomized trial

Delivery of human immunodeficiency virus (HIV) testing, treatment and adherence support integrated into sexual and reproductive health services for youth in Zimbabwe did not improve population-level HIV viral suppression over standard care, largely due to a substantial proportion of youth with undiagnosed HIV—highlighting implementation challenges to achieve UNAIDS 90-90-90 targets.

Rashida A. Ferrand
Ethel Dauya
Richard J. Hayes
ResearchOpen Access24 Jun 2025
Nature Medicine

Volume: 31, P: 3081-3088
Protein–DNA and protein–hormone interactions in prealbumin: a model of the thyroid hormone nuclear receptor?

C. C. F. Blake
S. J. Oatley
Research14 Jul 1977
Nature

Volume: 268, P: 115-120
Plutonium-244 in the Early Solar System

J. H. REYNOLDS
Research15 Jun 1968
Nature

Volume: 218, P: 1024-1028
Thermal Alteration as a Contributory Process to the Genesis of Petroleum

W. HENDERSON
G. EGLINTON
J. E. LOVELOCK
Research07 Sept 1968
Nature

Volume: 219, P: 1012-1016
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

A meta-analysis of genome-wide association studies of type 2 diabetes (T2D) identifies more than 600 T2D-associated loci; integrating physiological trait and single-cell chromatin accessibility data at these loci sheds light on heterogeneity within the T2D phenotype.

Ken Suzuki
Konstantinos Hatzikotoulas
Eleftheria Zeggini
ResearchOpen Access19 Feb 2024
Nature

Volume: 627, P: 347-357
Winds in the thermosphere of the Northern Polar Cap

R. W. Smith
P. J. Sweeney
Research03 Apr 1980
Nature

Volume: 284, P: 437-438
Electrolytic Polishing of Zinc

W. H. J. VERNON
E. G. STROUD
Research31 Dec 1938
Nature

Volume: 142, P: 1161
Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms

ROBERT G. ROEDER
WILLIAM J. RUTTER
Research18 Oct 1969
Nature

Volume: 224, P: 234-237
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

A. Kamb
D. Shattuck-Eidens
L. A. Cannon-Albright
Research01 Sept 1994
Nature Genetics

Volume: 8, P: 22-26
Ground-based imaging of extrasolar planets using adaptive optics

J. R. P. Angel
Research17 Mar 1994
Nature

Volume: 368, P: 203-207
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Genome-wide association and fine-mapping analyses in ancestrally diverse populations implicate candidate causal genes and mechanisms underlying type 2 diabetes. Trans-ancestry genetic risk scores enhance transferability across populations.

Anubha Mahajan
Cassandra N. Spracklen
Andrew P. Morris
Research12 May 2022
Nature Genetics

Volume: 54, P: 560-572
Scaling of heating rates in solar coronal loops

James A. Klimchuk
Lisa J. Porter
Research14 Sept 1995
Nature

Volume: 377, P: 131-133
Late type giants in Large Magellanic Cloud

VICTOR M. BLANCO
S.J. MARTIN F. MCCARTHY
Research04 Dec 1975
Nature

Volume: 258, P: 407-408
Scattered Arrangement of the Bacterial Ribosomal Cistrons

I. PURDOM
J. O. BISHOP
M. L. BIRNSTIEL
Research18 Jul 1970
Nature

Volume: 227, P: 239-242
Sequence analysis of immunoglobulin light chain messenger RNA

C. Milstein
G. G. Brownlee
N. J. Proudfoot
Research29 Nov 1974
Nature

Volume: 252, P: 354-359
Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like ancestors

Phylogenetic reconstructions with conserved protein markers from the 11 known DPANN phyla reveal their monophyletic placement within the Euryarchaeota.

Brittany A. Baker
Charley G. P. McCarthy
David Moreira
Research17 Jun 2025
Nature Microbiology

Volume: 10, P: 1593-1604
A low resolution structure for the histone core of the nucleosome

A. Klug
D. Rhodes
J. O. Thomas
Research09 Oct 1980
Nature

Volume: 287, P: 509-516
Concept of Human Atherosclerosis

K. J. KINGSBURY
Research11 Oct 1969
Nature

Volume: 224, P: 146-149
The observability of possible atmospheric removal processes for chlorfluorocarbons 11 and 12

Robert J. Gelinas
David K. Hall
Robert G. Nelson
Research01 Mar 1977
Nature

Volume: 266, P: 229-231
Generation of Cherenkov Light Flashes by Cosmic Radiation within the Eyes of the Apollo Astronauts

G. G. FAZIO
J. V. JELLEY
W. N. CHARMAN
Research17 Oct 1970
Nature

Volume: 228, P: 260-264
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Andrew Morris, Mark McCarthy, Michael Boehnke and colleagues report a meta-analysis of genome-wide association studies for type 2 diabetes, including 26,488 cases and 83,964 controls from populations of European, east Asian, south Asian and Mexican and Mexican American ancestry. They identify seven loci newly associated with type 2 diabetes and examine the genetic architecture of disease across populations.

Anubha Mahajan
Min Jin Go
Andrew P Morris
Research09 Feb 2014
Nature Genetics

Volume: 46, P: 234-244
Determination of Diffusion Coefficients of Haemocyanin at Low Concentration by Intensity Fluctuation Spectroscopy of Scattered Laser Light

R. FOORD
E. JAKEMAN
A. R. PEACOCKE
Research18 Jul 1970
Nature

Volume: 227, P: 242-245
Substrate Hydrophobic Groups and the Maximal Rate of Enzyme Reactions

BAREND H. J. HOFSTEE
Research07 Jan 1967
Nature

Volume: 213, P: 42-44
Electron Micrography of Antibody-Producing Cells

A. E. BUSSARD
J. L. BINET
Research01 Feb 1965
Nature

Volume: 205, P: 675-678
Action of Urea on the Activity of Dehydrogenases and α-Glucosidase in Aerobacter aerogenes grown in Continuous Culture

A. C. R. DEAN
P. J. RODGERS
Research08 Mar 1969
Nature

Volume: 221, P: 969-971
Transposition protein of Tn3: identification and characterisation of an essential represser-controlled gene product

Joany Chou
Peggy G. Lemaux
Stanley N. Cohen
Research20 Dec 1979
Nature

Volume: 282, P: 801-806
Ability of Tamarins to Produce and Respond to Erythropoietin

E. A. MIRAND
T. C. PRENTICE
J. T. GRACE jun.
Research01 Dec 1964
Nature

Volume: 204, P: 1064-1066
Comparative Effectiveness of Adenosine Analogues as Inhibitors of Blood-Platelet Aggregation and as Vasodilators in Man

G. V. R. BORN
R. J. HASLAM
R. D. LOWE
Research01 Feb 1965
Nature

Volume: 205, P: 678-680
The Enzyme Electrode

S. J. UPDIKE
G. P. HICKS
Research01 Jun 1967
Nature

Volume: 214, P: 986-988
Transient X-ray sources

D. H. CLARK
J. H. PARKINSON
Research04 Dec 1975
Nature

Volume: 258, P: 408-409
The credibility of machine intelligence

We usually use our previous experience in solving a present problem, and ‘intelligence’ is the name of the mechanism by which we do this. A programmed computer should not be deemed intelligent unless it is functionally similar to the brain in its use of previous experience.

J. R. Ullmann
Research16 Oct 1975
Nature

Volume: 257, P: 547-549
Isoprenoid thiophenes: novel products of sediment diagenesis?

S. C. Brassell
C. A. Lewis
J. S. Sinninghe Damsté
Research13 Mar 1986
Nature

Volume: 320, P: 160-162
Photochemistry of Anthraquinone Dyes in Solution and in Polymer Masses

G. S. EGERTON
J. M. GLEADLE
A. G. ROACH
Research25 Apr 1964
Nature

Volume: 202, P: 345-347
In Vitro Activation of Adenylate Cyclase of Atrophic Celiac Intestinal Mucosa by Wheat Gliadin-Derived Peptides

L Beguinot
S Auricchio
V Silano
Research01 Jan 1986
Pediatric Research

Volume: 20, P: 42-44
Structural Units in Chromatin and their Orientation on Membranes

H. G. DAVIES
J. V. SMALL
Research23 Mar 1968
Nature

Volume: 217, P: 1122-1125
Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models of neurodevelopmental disorders

Caldwell et al. provide a resource of astrocyte-secreted proteins from models of neurodevelopmental disorders and use this to identify upregulated levels of the IGF inhibitor Igfbp2 as contributing to neural developmental deficits in Rett syndrome.

Alison L. M. Caldwell
Laura Sancho
Nicola J. Allen
Research30 Aug 2022
Nature Neuroscience

Volume: 25, P: 1163-1178
Reproduction of the Viruses isolated from Cases of Infectious Hepatitis on Detroit-6(VA) Cell Line

J. LÁSZLÓ
E. BÁLINT
SUSANA ALMÁSI
Research17 Jul 1965
Nature

Volume: 207, P: 326-327
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Ruth Loos and colleagues report results of a large genome-wide association study for body mass index. They identify 18 new loci associated with this trait, some of which map near key hypothalamic regulators of energy balance.

Elizabeth K Speliotes
Cristen J Willer
Ruth J F Loos
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 937-948
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Kyle Gaulton, Mark McCarthy, Andrew Morris and colleagues report fine mapping and genomic annotation of 39 established type 2 diabetes susceptibility loci. They find that the set of potential causal variants is enriched for overlap with FOXA2 binding sites in human islet and liver cells, and they show that a likely causal variant near MTNR1B increases FOXA2-bound enhancer activity, providing a molecular mechanism to explain the effect of this locus on disease risk.

Kyle J Gaulton
Teresa Ferreira
Andrew P Morris
Research09 Nov 2015
Nature Genetics

Volume: 47, P: 1415-1425
Significance of the even-carbon n-paraffin preference of a Spanish crude oil

J. ALBAIGES
J. M. TORRADAS
Research01 Aug 1974
Nature

Volume: 250, P: 567-568

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