Little is known about how the plant-infecting cowpea mosaic virus (CPMV)—an invaluable tool in several biotechnology applications—packages its single-strand RNA genome into the capsid. Here the authors present two high-resolution cryo-EM structures of CPMV and a new model for RNA recognition and capsid assembly.
- Emma L. Hesketh
- Yulia Meshcheriakova
- Neil A. Ranson