Nature Search

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Structure of ADP·AIF₄^–-stabilized nitrogenase complex and its implications for signal transduction

Hermann Schindelin
Caroline Kisker
Douglas C. Rees
Research22 May 1997
Nature

Volume: 387, P: 370-376
Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

Deep brain stimulation and epidural electrical stimulation of the spinal cord enable locomotion in humans with spinal cord injury (SCI) but the potential synergy between both approaches is unclear. The authors show that a complex technological approach is required to enable volitional walking in rats with SCI.

Marco Bonizzato
Nicholas D. James
Gregoire Courtine
ResearchOpen Access26 Mar 2021
Nature Communications

Volume: 12, P: 1-14
Modern archaeomonads indicate sea-ice environments

James G. Mitchell
Mary W. Silver
Research01 Apr 1982
Nature

Volume: 296, P: 437-439
Design and synthesis of multi-haem proteins

Dan E. Robertson
Ramy S. Farid
P. Leslie Dutton
Research31 Mar 1994
Nature

Volume: 368, P: 425-432
Comprehensive molecular characterization of mitochondrial genomes in human cancers

Analysis of mitochondrial genomes (mtDNA) by using whole-genome sequencing data from 2,658 cancer samples across 38 cancer types identifies hypermutated mtDNA cases, frequent somatic nuclear transfer of mtDNA and high variability of mtDNA copy number in many cancers.

Yuan Yuan
Young Seok Ju
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Genetics

Volume: 52, P: 342-352
Studies on Ciliary Dyskinesia Factor in Cystic Fibrosis. II. Short Term Leukocyte Cultures and Long Term Lymphoid Lines

James H Conover
Nicholas G Beratis
Kurt Hirschhorn
Research01 Apr 1973
Pediatric Research

Volume: 7, P: 224-228
Association between COVID-19 vaccine efficacy and epidemic force of infection

Jing Xu
M. Elizabeth Halloran
Yunda Huang
ResearchOpen Access17 Jan 2026
npj Vaccines

Volume: 11, P: 1-9
Ionospheric irregularities at Jupiter observed by JWST

JWST has revealed unexpected and complex emissions structures in the upper atmosphere of Jupiter, above the Great Red Spot. These features suggest that different atmospheric layers are strongly coupled by gravity waves.

Henrik Melin
J. O’Donoghue
M. R. Showalter
ResearchOpen Access21 Jun 2024
Nature Astronomy

Volume: 8, P: 1000-1007
Platinum and microspherule peaks as chronostratigraphic markers for onset of the Younger Dryas at Wakulla Springs, Florida

Christopher R. Moore
Mark J. Brooks
James K. Feathers
ResearchOpen Access20 Dec 2023
Scientific Reports

Volume: 13, P: 1-22
Diamagnetic Susceptibility of Heavy Water

V. C. G. TREW
JAMES F. SPENCER
Research13 Jun 1936
Nature

Volume: 137, P: 998
Generalisation of self-thinning of plant populations

JAMES WHITE
Research28 Jul 1977
Nature

Volume: 268, P: 373
Respiratory syncytial virus hospitalisation by chronological month of age and by birth month in infants

Passive immunisation for respiratory syncytial virus for infants is recommended by the World Health Organization but products currently available have limited duration of protection. Here, the authors investigate the age distribution of infant hospitalisation for respiratory syncytial virus to inform optimal timing of immunisation.

Ling Guo
Sebastien Kenmoe
Eva Molero
ResearchOpen Access03 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Genomic–transcriptomic evolution in lung cancer and metastasis

Computational and machine-learning approaches that integrate genomic and transcriptomic variation from paired primary and metastatic non-small cell lung cancer samples from the TRACERx cohort reveal the role of transcriptional events in tumour evolution.

Carlos Martínez-Ruiz
James R. M. Black
Nicholas McGranahan
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 543-552
Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreading

Lipid particles loaded with RNA coding for tumour-unspecific antigens can enhance early responses of type-I interferons, mediating the success of immune checkpoint inhibitors as well as epitope spreading.

Sadeem Qdaisat
Brandon Wummer
Elias J. Sayour
Research18 Jul 2025
Nature Biomedical Engineering

Volume: 9, P: 1437-1452
DNA-binding properties of the product of the testis-determining gene and a related protein

Nargis Nasrin
Colleen Buggs
Maria Alexander-Bridges
Research28 Nov 1991
Nature

Volume: 354, P: 317-320
Large-scale migration into Britain during the Middle to Late Bronze Age

Genome-wide ancient DNA data from individuals from the Middle Bronze Age to Iron Age documents large-scale movement of people from the European continent between 1300 and 800 bc that was probably responsible for spreading early Celtic languages to Britain.

Nick Patterson
Michael Isakov
David Reich
Research22 Dec 2021
Nature

Volume: 601, P: 588-594
Brain-wide neural recordings in mice navigating physical spaces enabled by robotic neural recording headstages

To avoid head fixation or drawbacks of miniaturized devices for freely moving rodents, a robotic device can move a headstage for microscopy or electrophysiology with the animal, thereby enabling naturalistic behavior.

James Hope
Travis M. Beckerle
Suhasa B. Kodandaramaiah
Research07 Oct 2024
Nature Methods

Volume: 21, P: 2171-2181
Algebraic methods and computational strategies for pseudoinverse-based MR image reconstruction (Pinv-Recon)

Kylie Yeung
Christine Tobler
Florian Wiesinger
ResearchOpen Access30 Oct 2025
Scientific Reports

Volume: 15, P: 1-19
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

Mixed responses to targeted therapy within a patient are a clinical challenge. Here the authors show that TP53 loss-of-function cooperates with whole genome doubling which increases chromosomal instability. This leads to greater cellular diversity and multiple routes of resistance, which in turn promotes mixed responses to treatment.

Sebastijan Hobor
Maise Al Bakir
Charles Swanton
ResearchOpen Access13 Jun 2024
Nature Communications

Volume: 15, P: 1-21
An enzyme–substrate complex involved in bacterial cell wall biosynthesis

Timothy E. Benson
David J. Filman
James M. Hogle
Research01 Aug 1995
Nature Structural Biology

Volume: 2, P: 644-653
Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

Jhumku D. Kohtz
Sharon F. Jamison
James L. Manley
Research10 Mar 1994
Nature

Volume: 368, P: 119-124
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Raymond K. Walters
Renato Polimanti
Arpana Agrawal
Research26 Nov 2018
Nature Neuroscience

Volume: 21, P: 1656-1669
Role of γ-interferon in antibody-producing responses

H. James Leibson
Malcolm Gefter
John W. Kappler
Research28 Jun 1984
Nature

Volume: 309, P: 799-801
Embryonal carcinoma stem cells lack a function required for virus replication

James W. Gautsch
Research08 May 1980
Nature

Volume: 285, P: 110-112
Expanded encyclopaedias of DNA elements in the human and mouse genomes

The authors summarize the data produced by phase III of the Encyclopedia of DNA Elements (ENCODE) project, a resource for better understanding of the human and mouse genomes.

Federico Abascal
Reyes Acosta
Zhiping Weng
ResearchOpen Access29 Jul 2020
Nature

Volume: 583, P: 699-710
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Whole-genome sequencing of 490,640 UK Biobank participants

A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation.

Keren Carss
Bjarni V. Halldorsson
Ole Schulz-Trieglaff
ResearchOpen Access06 Aug 2025
Nature

Volume: 645, P: 692-701
Structure of a human common cold virus and functional relationship to other picornaviruses

Michael G. Rossmann
Edward Arnold
Gerrit Vriend
Research12 Sept 1985
Nature

Volume: 317, P: 145-153
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
The evolution of non-small cell lung cancer metastases in TRACERx

A longitudinal evolutionary analysis of 126 lung cancer patients with metastatic disease reveals the timing of metastatic divergence, modes of dissemination and the genomic events subject to selection during the metastatic transition.

Maise Al Bakir
Ariana Huebner
Charles Swanton
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 534-542
Dicarboxylic acids from electric discharge

BEN ZEITMAN
SHERWOOD CHANG
JAMES G. LAWLESS
Research06 Sept 1974
Nature

Volume: 251, P: 42-43
Streamside trees that do not use stream water

Todd E. Dawson
James R. Ehleringer
Research28 Mar 1991
Nature

Volume: 350, P: 335-337
Plasmodium falciparum strain-specific antibody blocks binding of infected erythrocytes to amelanotic melanoma cells

Iroka J. Udeinya
Louis H. Miller
James B. Jensen
Research02 Jun 1983
Nature

Volume: 303, P: 429-431
Root Pressure Exudation from Apical Root Segments

JAMES W. O'LEARY
Research01 Oct 1966
Nature

Volume: 212, P: 96-97
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer.

Christopher Abbosh
Alexander M. Frankell
Charles Swanton
Research13 Apr 2023
Nature

Volume: 616, P: 553-562
Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

Joel B. Nelson
Sean P. Hedican
Jonathan W. Simons
Research01 Sept 1995
Nature Medicine

Volume: 1, P: 944-949
The evolution of lung cancer and impact of subclonal selection in TRACERx

Analyses of multiregional tumour samples from 421 patients with non-small cell lung cancer prospectively enrolled to the TRACERx study reveal determinants of tumour evolution and relationships between intratumour heterogeneity and clinical outcome.

Alexander M. Frankell
Michelle Dietzen
Charles Swanton
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 525-533
Homocysteine Metabolism in Scurvy, Growth and Arteriosclerosis

KILMER S. McCULLY
Research11 Jun 1971
Nature

Volume: 231, P: 391-392
The viral mousetrap

James Binley
John P. Moore
News & Views22 May 1997
Nature

Volume: 387, P: 346-348
Asparaginyl-tRNA and Resistance of Murine Leukaemias to L-Asparaginase

ROBERT C. GALLO
JAMES L. LONGMORE
RICHARD H. ADAMSON
Research12 Sept 1970
Nature

Volume: 227, P: 1134-1136
Specific distribution of metabolic alterations in cerebral cortex following apomorphine administration

James McCulloch
Helen E. Savaki
Louis Sokoloff
Research15 Nov 1979
Nature

Volume: 282, P: 303-305
Integrated radiogenomics models predict response to neoadjuvant chemotherapy in high grade serous ovarian cancer

Response to treatment in high grade serous ovarian carcinoma (HGSOC) is highly variable. Here, the authors leverage a radiogenomic model to predict neoadjuvant chemotherapy response in HGSOC, including clinical data, medical imaging, and blood-based biomarkers such as CA-125 and ctDNA features.

Mireia Crispin-Ortuzar
Ramona Woitek
James D. Brenton
ResearchOpen Access24 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Mouse spleen and IgD-secreting plasmacytomas contain multiple IgD δ chain RNAs

Leona Fitzmaurice
James Owens
J. Frederic Mushinski
Research01 Apr 1982
Nature

Volume: 296, P: 459-462
Focused ultrasound-microbubble treatment arrests the growth and formation of cerebral cavernous malformations

Central nervous system lesions are reduced following focused ultrasound treatment in a mouse model.

Delaney G. Fisher
Tanya Cruz
Richard J. Price
ResearchOpen Access13 May 2025
Nature Biomedical Engineering

Volume: 9, P: 1531-1546
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models

Patient-derived xenografts are important tools for cancer drug development. Here, the authors develop models from 22 non-small cell lung cancer patients. They show genomic differences between models created from different spatial regions of tumours and a bottleneck on model establishment.

Robert E. Hynds
Ariana Huebner
Charles Swanton
ResearchOpen Access31 May 2024
Nature Communications

Volume: 15, P: 1-21
RETRACTED ARTICLE: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

Medulloblastomas lacking p53 do not express surface class I major histocompatibility complex (MHC-I) and are resistant to immune rejection. Tumor necrosis factor rescues MHC-I expression and synergizes with immune checkpoint inhibitors to promote rejection.

Alexandra Garancher
Hiromichi Suzuki
Robert J. Wechsler-Reya
Research18 May 2020
Nature Neuroscience

Volume: 23, P: 842-853
The NMR structure of the inhibited catalytic domain of human stromelysin–1

Paul R. Gooley
John F. O'Connell
Bruce A. Johnson
Research01 Feb 1994
Nature Structural Biology

Volume: 1, P: 111-118
A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology

The authors identify genetic variation associated with properties of the internal biological structures of blood cells in hundreds of genes and show how such discoveries can be used to improve understanding of cellular mechanisms causing disease.

Parsa Akbari
Dragana Vuckovic
William J. Astle
ResearchOpen Access18 Aug 2023
Nature Communications

Volume: 14, P: 1-19
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Transancestral GWAS meta-analysis in 160,420 individuals identifies 139 loci associated with refractive error, including myopia. Newly identified genes implicate pathways involved in eye growth and light signaling cascades.

Milly S. Tedja
Robert Wojciechowski
Caroline C. W. Klaver
Research28 May 2018
Nature Genetics

Volume: 50, P: 834-848

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