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Showing 1–50 of 140 results

Advanced filters: Author: James E Rothman Clear advanced filters

Mechanisms of intracellular protein transport

James E. Rothman
Reviews03 Nov 1994
Nature

Volume: 372, P: 55-63
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

Tito Serafini
Gudrun Stenbeck
Felix T. Wieland
Research17 Jan 1991
Nature

Volume: 349, P: 215-220
SNAP receptors implicated in vesicle targeting and fusion

Thomas Söllner
Sidney W. Whiteheart
James E. Rothman
Research25 Mar 1993
Nature

Volume: 362, P: 318-324
A role for clathrin light chains in the recognition of clathrin cages by ‘uncoating ATPase’

Sandra L. Schmid
William A. Braell
James E. Rothman
Research20 Sept 1984
Nature

Volume: 311, P: 228-231
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

Duncan W. Wilson
Celeste A. Wilcox
James E. Rothman
Research01 Jun 1989
Nature

Volume: 339, P: 355-359
SNAP family of NSF attachment proteins includes a brain-specific isoform

Sidney W. Whiteheart
Irene C. Griff
James E. Rothman
Research25 Mar 1993
Nature

Volume: 362, P: 353-355
Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol

Lelio Orci
David J. Palmer
James E. Rothman
Research19 Aug 1993
Nature

Volume: 364, P: 732-734
Molecular dissection of the secretory pathway

A combination of biochemistry in animal cell-free systems and genetics in yeast is revealing the molecular machinery of the secretory pathway of eukaryotes. Transporting vesicles have a simple coat structure and employ a general mechanism for fusion that is conserved in evolution.

James E. Rothman
Lelio Orci
Reviews30 Jan 1992
Nature

Volume: 355, P: 409-415
Possible role for fatty acyl-coenzyme A in intracellular protein transport

Benjamin S. Glick
James E. Rothman
Research25 Mar 1987
Nature

Volume: 326, P: 309-312
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

Giuseppe Pantaleo
Cecilia Graziosi
Anthony S. Fauci
Research25 Mar 1993
Nature

Volume: 362, P: 355-358
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

J. Bernd Helms
James E. Rothman
Research26 Nov 1992
Nature

Volume: 360, P: 352-354
Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport

Ruben Diaz
Luis S. Mayorga
Philip D. Stahl
Research01 Jun 1989
Nature

Volume: 339, P: 398-400
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins

Lelio Orci
David J. Palmer
James E. Rothman
Research15 Apr 1993
Nature

Volume: 362, P: 648-652
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein

Con J. M. Beckers
Marc R. Block
William E. Balch
Research01 Jun 1989
Nature

Volume: 339, P: 397-398
Peptide-binding specificity of the molecular chaperone BiP

Gregory C. Flynn
Jan Pohl
James E. Rothman
Research24 Oct 1991
Nature

Volume: 353, P: 726-730
Synchronised transmembrane insertion and glycosylation of a nascent membrane protein

James E. Rothman
Harvey F. Lodish
Research27 Oct 1977
Nature

Volume: 269, P: 775-780
'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles

M. Gerard Waters
Tito Serafini
James E. Rothman
Research17 Jan 1991
Nature

Volume: 349, P: 248-251
A possible docking and fusion particle for synaptic transmission

Giampietro Schiavo
Michael J. S. Gmachl
James E. Rothman
Research14 Dec 1995
Nature

Volume: 378, P: 733-736
Cell biology: An unfolding story of protein translocation

James E. Rothman
Roger D. Kornberg
News & Views17 Jul 1986
Nature

Volume: 322, P: 209-210
Is volcanic ash a pneumoconiosis risk?

Francis H. Y. Green
Val Vallyathan
Philip Parshley
Research17 Sept 1981
Nature

Volume: 293, P: 216-217
Cell biology: Life without clathrin

James E. Rothman
News & Views09 Jan 1986
Nature

Volume: 319, P: 96-97
Two successive oligomeric Munc13 assemblies scaffold vesicle docking and SNARE assembly to support neurotransmitter release

The presynaptic protein Munc13 forms nanoclusters at synaptic release sites, but its internal organization is unclear. Here, the authors show that two distinct ordered Munc13 oligomers couple synaptic vesicle docking and SNARE assembly to regulate neurotransmission

Manindra Bera
Kirill Grushin
Jeremy S. Dittman
ResearchOpen Access05 Aug 2025
Nature Communications

Volume: 16, P: 1-18
Phospholipid transfer market

James E. Rothman
News & Views01 Oct 1990
Nature

Volume: 347, P: 519-520
Apolipoprotein B intermediates

RICHARD PEASE
GEORGINA HARRISON
JAMES SCOTT
Research12 Mar 1992
Nature

Volume: 356, P: 115-116
GTP and methionine bristles

James E. Rothman
News & Views10 Aug 1989
Nature

Volume: 340, P: 433-434
In Vivo Measurement of Phenylalanine in Human Brain by Proton Nuclear Magnetic Resonance Spectroscopy

Edward J Novotny JR.
Malcolm J Avison
Douglas L Rothman
Research01 Feb 1995
Pediatric Research

Volume: 37, P: 244-249
Determination of the spin and parity of all-charm tetraquarks

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

A. Hayrapetyan
V. Makarenko
A. Snigirev
ResearchOpen Access03 Dec 2025
Nature

Volume: 648, P: 58-63
All-optical visualization of specific molecules in the ultrastructural context of brain tissue

Pan-expansion microscopy of tissue combines staining of proteins and lipids with immunolabeling.

Ons M’Saad
Allison Cairns
Joerg Bewersdorf
ResearchOpen Access26 Nov 2025
Nature Biotechnology

P: 1-15
Two-colour live-cell nanoscale imaging of intracellular targets

The intracellular applications of STED microscopy are limited by the availability of dyes. Here the authors develop a two-colour labelling strategy based on SiR and ATTO590 dyes, and apply their strategy to image various subcellular membrane compartments.

Francesca Bottanelli
Emil B. Kromann
Joerg Bewersdorf
ResearchOpen Access04 Mar 2016
Nature Communications

Volume: 7, P: 1-5
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
Familial combined hyperlipidaemia linked to the apolipoprotein AI–CIII–AIV gene cluster on chromosome 11q23q–q24

Andrew P. Wojciechowski
Martin Farrall
James Scott
Research10 Jan 1991
Nature

Volume: 349, P: 161-164
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and show the utility of polygenic risk scores may vary depending on cancer type.

Yan Dora Zhang
Amber N. Hurson
Montserrat Garcia-Closas
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-13
A consensus immune dysregulation framework for sepsis and critical illnesses

In an integrated analysis of transcriptomic data from the SUBSPACE consortium and public datasets of patients with sepsis, acute respiratory distress syndrome, trauma and burns, dysregulation within four consensus molecular clusters related to myeloid and lymphoid cells is associated with mortality and illness severity.

Andrew R. Moore
Hong Zheng
Purvesh Khatri
ResearchOpen Access30 Sept 2025
Nature Medicine

Volume: 31, P: 4084-4096
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins

Robert A. Obar
Christine A. Collins
Richard B. Vallee
Research20 Sept 1990
Nature

Volume: 347, P: 256-261
Sequestration of the membrane-targeting myristoyl group of recoverin in the calcium-free state

Toshiyuki Tanaka
James B. Amest
Mitsuhiko lkura
Research03 Aug 1995
Nature

Volume: 376, P: 444-447
A transcriptional hierarchy involved in mammalian cell-type specification

Calvin J. Kuo
Pamela B. Conley
Gerald R. Crabtree
Research30 Jan 1992
Nature

Volume: 355, P: 457-461
Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

A multi-ancestry genome-wide association meta-analysis of kidney cancer identifies 63 regions associated with disease susceptibility including one locus that was associated with increased risk in individuals with African ancestry.

Mark P. Purdue
Diptavo Dutta
Stephen J. Chanock
Research26 Apr 2024
Nature Genetics

Volume: 56, P: 809-818
Elliptic anisotropy measurement of the f₀(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A. Hayrapetyan
A. Tumasyan
A. Zhokin
ResearchOpen Access27 Aug 2025
Nature Communications

Volume: 16, P: 1-19
A combination of a particular HLA-DPβ allele and an HLA-DQ heterodimer confers susceptibility to coeliac disease

Teodorica L. Bugawan
Giovanna Angelini
Henry A. Erlich
Research08 Jun 1989
Nature

Volume: 339, P: 470-473
Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia

Chronic lymphocytic leukemia is a highly inheritable cancer. Here the authors conduct a metaanalysis of four genome-wide association studies and identify three novel loci located near EOMES, SERPINB6 and LPPassociated with risk of this disease.

Sonja I. Berndt
Nicola J. Camp
Susan L. Slager
ResearchOpen Access09 Mar 2016
Nature Communications

Volume: 7, P: 1-9
A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Marginal zone lymphoma (MZL) is a common subtype of B-cell non-Hodgkin lymphoma. Here the authors carry out a two-stage genome-wide association study in over 8,000 Europeans and identify two new MZL risk loci at chromosome 6p, implicating the major histocompatibility complex in the disease for the first time.

Joseph Vijai
Zhaoming Wang
Alexandra Nieters
ResearchOpen Access08 Jan 2015
Nature Communications

Volume: 6, P: 1-7
Genome-wide association study identifies multiple risk loci for renal cell carcinoma

Risk for renal cell carcinoma (RCC) is higher when there are first-degree family members with the disease. Here, Scelo and colleagues perform a genome-wide association meta-analysis and new genome-wide scan to identify seven new loci with significant RCC association.

Ghislaine Scelo
Mark P. Purdue
Stephen J. Chanock
ResearchOpen Access09 Jun 2017
Nature Communications

Volume: 8, P: 1-9
Role of ion flux in the control of c-fos expression

James I. Morgan
Tom Curran
Research07 Aug 1986
Nature

Volume: 322, P: 552-555
β-Arrestin acts as a clathrin adaptor in endocytosis of the β₂-adrenergic receptor

Oscar B. Goodman Jr
Jason G. Krupnick
Jeffrey L. Benovic
Research03 Oct 1996
Nature

Volume: 383, P: 447-450
Transient and sustained activity in a distributed neural system for human working memory

Susan M. Courtney
Leslie G. Ungerleider
James V. Haxby
Research10 Apr 1997
Nature

Volume: 386, P: 608-611
Expression of transcription factor E2F1 induces quiescent cells to enter S phase

David G. Johnson
James K. Schwarz
Joseph R. Nevins
Research23 Sept 1993
Nature

Volume: 365, P: 349-352
Genetic linkage of Werner's syndrome to five markers on chromosome 8

Makoto Goto
Mark Rubenstein
Dennis Drayna
Research20 Feb 1992
Nature

Volume: 355, P: 735-738
Effect of methylprednisolone in cervical spinal cord injury stratified by injury severity: analysis in 908 patients

Tetsuhiko Mimura
Ali Moghaddamjou
Michael G. Fehlings
Research08 Jan 2026
Spinal Cord

Volume: 64, P: 177-185
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia has a hereditary component, much of which remains to be identified. Here, the authors perform a genome-wide association study and find new risk loci for the disease, which are associated with genes involved in immune function.

Philip J. Law
Sonja I. Berndt
Susan Slager
ResearchOpen Access06 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

Susan Slager and colleagues report a meta-analysis of genome-wide association studies for chronic lymphocytic leukemia (CLL). They identify nine loci newly associated with CLL.

Sonja I Berndt
Christine F Skibola
Susan L Slager
Research16 Jun 2013
Nature Genetics

Volume: 45, P: 868-876

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