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Nature Communications (13)
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Showing 1–50 of 51 results

Advanced filters: Author: Jiani Yang Clear advanced filters

RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity

Cell state plasticity of neuroblastoma cells is linked to therapy resistance. Here, the authors develop a transcriptomic and epigenetic map of indisulam (RBM39 degrader) resistant neuroblastoma, demonstrating bidirectional cell state switching accompanied by increased NK cell activity, which they therapeutically enhance by the addition of an anti-GD2 antibody.

Shivendra Singh
Jie Fang
Jun Yang
ResearchOpen Access17 Sept 2025
Nature Communications

Volume: 16, P: 1-26
Homologous heteropolyaromatic covalent organic frameworks for enhancing photocatalytic hydrogen peroxide production and aerobic oxidation

Developing robust catalysts that work under harsh conditions for photocatalysis is challenging. Here, the authors report the design of thiazole-based homologous hetero-polyaromatic covalent organic frameworks via post-cyclization reaction for photocatalytic H₂O₂ production and aerobic oxidation.

Jiani Yang
Zhenyang Zhao
Chong Cheng
ResearchOpen Access17 Aug 2025
Nature Communications

Volume: 16, P: 1-15
Astrocyte-secreted cues promote neural maturation and augment activity in human forebrain organoids

Current brain organoids protocols face significant challenges in achieving adequate neural maturation to effectively replicate the functionality of mature neural circuits. Here, authors present an approach by integrating astrocyte-secreted factors to facilitate maturation and functional fidelity of in vitro brain organoids and planar neural cultures.

Honghui Zheng
Yilin Feng
Shaohua Ma
ResearchOpen Access23 Mar 2025
Nature Communications

Volume: 16, P: 1-19
Publisher Correction: Metal–support frontier orbital interactions in single-atom catalysis

Xianxian Shi
Zhilin Wen
Junling Lu
Amendments and Corrections04 Jun 2025
Nature

Volume: 642, P: E25
Proteogenomic characterization reveals tumorigenesis and progression of lung cancer manifested as subsolid nodules

Understanding the development of subsolid nodules (SSNs) in lung adenocarcinoma (LUAD) is important for their clinical management. Here, the authors perform proteogenomic analysis of 66 LUAD displayed as SSNs from 3 histological stages and highlight the role of endoplasmic reticulum stress in progression.

Hang Su
Li Chen
Haipeng Liu
ResearchOpen Access11 Mar 2025
Nature Communications

Volume: 16, P: 1-19
Author Correction: Sequence terminus dependent PCR for site-specific mutation and modification detection

Gaolian Xu
Hao Yang
Hongchen Gu
Amendments and CorrectionsOpen Access20 Mar 2023
Nature Communications

Volume: 14, P: 1-2
Fibrosis quantification in Hypertensive Heart Disease with LVH and Non-LVH: Findings from T1 mapping and Contrast-free Cardiac Diffusion-weighted imaging

Lian-Ming Wu
Rui Wu
Jian-Rong Xu
ResearchOpen Access03 Apr 2017
Scientific Reports

Volume: 7, P: 1-9
Metal–support frontier orbital interactions in single-atom catalysis

The acetylene hydrogenation activity and stability of a palladium single-atom catalyst are both controlled by the lowest unoccupied molecular orbital of the oxide support.

Xianxian Shi
Zhilin Wen
Junling Lu
Research02 Apr 2025
Nature

Volume: 640, P: 668-675
Associations of digestive diseases exposure and lifestyle factors with Parkinson’s disease

Kaitai Yang
Ruitian Zeng
Guoen Cai
ResearchOpen Access18 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Single-cell transcriptomic landscape deciphers olfactory neuroblastoma subtypes and intra-tumoral heterogeneity

Yu and colleagues present a single-cell transcriptomic landscape of olfactory neuroblastoma, characterizing different tumor subtypes and cancer cell responses to drug treatments.

Jingyi Yang
Xiaole Song
Hongmeng Yu
Research14 Nov 2024
Nature Cancer

Volume: 5, P: 1919-1939
Sequence terminus dependent PCR for site-specific mutation and modification detection

Rapid and facile detection of specific nucleic acid modifications could have numerous applications. Here the authors present Specific Terminal Mediated Polymerase Chain Reaction (STEM-PCR) as a generic and accessible approach, and demonstrate proof-of-principle cancer biomarker detection.

Gaolian Xu
Hao Yang
Hongchen Gu
ResearchOpen Access01 Mar 2023
Nature Communications

Volume: 14, P: 1-11
VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of bla_NDM-5 in zoonotic bacteria

Carbapenem-resistant Escherichia coli, carrying bla_NDM-5-IncX3 plasmids, can persist in chickens either under the presence of amoxicillin or without any antibiotic. Transcriptional regulator VirBR can promote transmission of IncX3 plasmid and persistence of bla_NDM-5 in zoonotic bacteria.

Tengfei Ma
Ning Xie
Jianzhong Shen
ResearchOpen Access28 Jun 2024
Nature Communications

Volume: 15, P: 1-13
Regulatory variation controlling architectural pleiotropy in maize

Pleiotropy is the effect of a single locus on multiple traits, which can lead to undesirable outcomes during crop improvement. Here, the authors reveal regulatory variation controlling pleiotropy between maize leaf angle and tassel branching, two important agronomic traits.

Edoardo Bertolini
Brian R. Rice
Andrea L. Eveland
ResearchOpen Access03 Mar 2025
Nature Communications

Volume: 16, P: 1-18
Effect of ion-specific water structures at metal surfaces on hydrogen production

Water structures at the electrolyte and electrode interfaces are crucial for electrochemical reactions. Here, the authors report that alkali metal cations can modify two-dimensional water networks at charged surfaces, impacting both reaction kinetics and efficiency.

Ye Tian
Botao Huang
Ying Jiang
ResearchOpen Access07 Sept 2024
Nature Communications

Volume: 15, P: 1-10
SPAT inhibits LUAD metastasis by targeting SF1-mediated splicing

Yun Ma
Xiaoxu Zhou
Pengyuan Liu
ResearchOpen Access08 Aug 2025
Cell Death & Disease

Volume: 16, P: 1-13
Identification of a longevity gene through evolutionary rate covariation of insect mito-nuclear genomes

By analyzing co-evolution of mitochondrial and nuclear genomes across insect species, the authors uncover the evolutionary covariation of a group of non-mitochondrially targeted nuclear genes with mitochondrial genes, including the uncharacterized gene CG11837, which regulates insect lifespan.

Mei Tao
Jiani Chen
Xing-Xing Shen
Research04 Jun 2024
Nature Aging

Volume: 4, P: 1076-1088
Evaluating the role of large language models in traditional Chinese medicine diagnosis and treatment recommendations

Yu Liu
Yishan Yuan
Jian Kong
ResearchOpen Access21 Jul 2025
npj Digital Medicine

Volume: 8, P: 1-12
The genome of Acorus deciphers insights into early monocot evolution

Monocots are one of the most diverse and dominant clades of flowering plants. Here, the authors assemble the genome of Acorus gramineus, confirm its phylogenetic position as sister to the rest of monocots and reveal the absence of tau (τ) whole-genome duplication observed in the majority of monocot clades.

Xing Guo
Fang Wang
Huan Liu
ResearchOpen Access20 Jun 2023
Nature Communications

Volume: 14, P: 1-15
Climate-driven patterns of global tree longevity

Trees in harsh environments exhibit higher longevity globally, particularly arid-adaptive gymnosperms whose extended longevity is linked to slow growth rates and high drought resilience, as revealed by 219,000 tree-ring width records from 4880 sites.

Jiani Gao
Keyan Fang
Zhengtang Guo
ResearchOpen Access31 Jul 2025
Communications Earth & Environment

Volume: 6, P: 1-9
A bimodal distribution of haze in Pluto’s atmosphere

Pluto’s haze is revealed to have two types of particles: small spherical organic haze particles and micron-size fluffy aggregates. The persistence of these two populations has important implications for haze formation and properties on icy worlds.

Siteng Fan
Peter Gao
Yuk L. Yung
ResearchOpen Access11 Jan 2022
Nature Communications

Volume: 13, P: 1-11
EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming

Triple-negative breast cancer is an aggressive form of the disease. Here, the authors identify EGFL9 as a mediator of metastasis in TNBC through interactions with cMET.

Fanyan Meng
Ling Wu
Guojun Wu
ResearchOpen Access06 Nov 2019
Nature Communications

Volume: 10, P: 1-17
Chromosome-level genome assembly of the threatened ornamental plant Hibiscus yunnanensis

Bishal Gurung
Jiani Li
Gao Chen
ResearchOpen Access25 Mar 2025
Scientific Data

Volume: 12, P: 1-7
Surface oxygen concentration differs between dry and ice-snow melting bare lands on the Tibetan Plateau

Wei Jia
Yujun Ma
Jiani Wu
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Changes in the assembly and functional adaptation of endophytic microbial communities in Amorphophallus species with different levels of resistance to necrotrophic bacterial pathogen stress

A study on the response of different resistant Amorphophallus species to Pcc stress reveals that endophytic fungal taxa play a key role in host plant’s defense against necrotizing bacterial pathogens.

Min Yang
Ying Qi
Lei Yu
ResearchOpen Access19 May 2025
Communications Biology

Volume: 8, P: 1-16
Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D

Citrullinated IGF2BP1 enhances the aggressiveness of fibroblast-like synoviocytes by increasing the mRNA stability of SEMA3D, autoantibodies against citrullinated IGF2BP1 are detected in patients with rheumatoid arthritis and positively correlate with disease severity.

Yang Qin
Li Liu
Xinyu Yang
ResearchOpen Access14 Jan 2025
Communications Biology

Volume: 8, P: 1-13
Mevalonate kinase inhibits anti-tumor immunity by impairing the tumor cell-intrinsic interferon response in microsatellite instability colorectal cancer

Yuanyu Liao
Rui Yang
Yanqiao Zhang
Research26 Dec 2024
Oncogene

Volume: 44, P: 944-957
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

The cellular heterogeneity in brain obscures the identification of robust cellular regulatory networks. Here the authors integrate genome-wide chromosome conformation data from sorted neurons and glia, with transcriptomic and enhancer profiles, to characterize cell-type-specific gene regulatory landscapes in the human brain, and provide insights into cell-type-specific gene regulatory networks in brain disorders.

Benxia Hu
Hyejung Won
Daniel H. Geschwind
ResearchOpen Access25 Jun 2021
Nature Communications

Volume: 12, P: 1-13
IGF2BP3 recruits NUDT21 to regulate SPTBN1 alternative polyadenylation and drive ovarian cancer progression

IGF2BP3 recruits NUDT21 to the m6A-modified site of SPTBN1, promoting alternative polyadenylation and generating oncogenic short transcripts in ovarian cancer. The long isoform suppresses tumor growth by binding CDK1 and blocking the G2/M phase.

Xin Luo
Lingcui Xie
Jing Xu
ResearchOpen Access29 Apr 2025
Communications Biology

Volume: 8, P: 1-13
Staphylococcus aureus SaeRS impairs macrophage immune functions through bacterial clumps formation in the early stage of infection

Mingzhang Li
Boyong Wang
Hao Shen
ResearchOpen Access06 Oct 2024
npj Biofilms and Microbiomes

Volume: 10, P: 1-16
Landscape of potentially targetable receptor tyrosine kinase fusions in diverse cancers by DNA-based profiling

Tiantian Wang
Li Wei
Zhe Wang
ResearchOpen Access11 Nov 2022
npj Precision Oncology

Volume: 6, P: 1-11
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells

Large tumors induce anemia and expansion of CD45⁺ immature erythroid cells, which represent a major immunosuppressive population in the spleen, contributing to systemic suppression of T cell immunity in late-stage cancer.

Lintao Zhao
Ran He
Bo Zhu
Research08 Oct 2018
Nature Medicine

Volume: 24, P: 1536-1544
Development and validation for prognostic nomogram of epithelial ovarian cancer recurrence based on circulating tumor cells and epithelial–mesenchymal transition

Jiani Yang
Jun Ma
Yu Wang
ResearchOpen Access22 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Functional dynamics analysis of endophytic microbial communities during Amorphophallus muelleri seed maturation

Min Yang
Yongteng Zhao
Lei Yu
ResearchOpen Access18 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Autophagy facilitates age-related cell apoptosis—a new insight from senile cataract

Jiani Huang
Wangshu Yu
Wei Han
ResearchOpen Access10 Jan 2022
Cell Death & Disease

Volume: 13, P: 1-15
Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes

Jiani Yin
Wu Chen
Christian P. Schaaf
ResearchOpen Access03 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
Investigating the causal impact of gut microbiota on arthritis via inflammatory proteins using mendelian randomization

Bingxiao Pan
Qihao Guo
Yang Wang
ResearchOpen Access10 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Mutations in ASH1L confer susceptibility to Tourette syndrome

Shiguo Liu
Miaomiao Tian
Ji-Song Guan
Research31 Oct 2019
Molecular Psychiatry

Volume: 25, P: 476-490
Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

Fei Li
Diping Song
Daniel S. W. Ting
ResearchOpen Access22 Sept 2020
npj Digital Medicine

Volume: 3, P: 1-8
Characteristics of Amorphophallus konjac as indicated by its genome

Lifang Li
Min Yang
Lei Yu
ResearchOpen Access19 Dec 2023
Scientific Reports

Volume: 13, P: 1-12
Metformin suppresses the growth of colorectal cancer by targeting INHBA to inhibit TGF-β/PI3K/AKT signaling transduction

Qing Xiao
Jiani Xiao
Gang Yin
ResearchOpen Access02 Mar 2022
Cell Death & Disease

Volume: 13, P: 1-14
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system

Yangyang Zhu
Hao Zhang
Longping Wen
Research14 Sept 2022
Cell Death & Differentiation

Volume: 30, P: 168-183
Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling

Dongdong Sun
Weiwei Tao
Haibo Cheng
ResearchOpen Access27 Aug 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-3
Spontaneous hyperactivity in Ash1l mutant mice, a new model for Tourette syndrome

Shiguo Liu
Miaomiao Tian
Ji-Song Guan
Research21 Jan 2020
Molecular Psychiatry

Volume: 25, P: 241-242
A tablet-based multi-dimensional drawing system can effectively distinguish patients with amnestic MCI from healthy individuals

Xiaonan Zhang
Liangliang Lv
Yang Li
ResearchOpen Access10 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Forecasting the progression of human civilization on the Kardashev Scale through 2060 with a machine learning approach

Antong Zhang
Jiani Yang
Siteng Fan
ResearchOpen Access12 Jul 2023
Scientific Reports

Volume: 13, P: 1-10
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway

Chunsik Lee
Rongyuan Chen
Xuri Li
ResearchOpen Access18 Aug 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-14
The species coalescent indicates possible bat and pangolin origins of the COVID-19 pandemic

Jialin Yang
Michael Skaro
Jonathan Arnold
ResearchOpen Access05 Apr 2023
Scientific Reports

Volume: 13, P: 1-13
High light and temperature reduce photosynthetic efficiency through different mechanisms in the C₄ model Setaria viridis

Anderson, Mattoon et al. exposed the C₄ model plant green foxtail Setaria viridis to four-hour periods of high light or high temperature and observed transcriptomic, photosynthetic, and ultrastructural changes. Both treatments caused a comparable reduction in photosynthetic efficiency, but the authors identified important differences in key pathways and differential responses in the mesophyll and bundle sheath cells in response to these two treatments.

Cheyenne M. Anderson
Erin M. Mattoon
Ru Zhang
ResearchOpen Access16 Sept 2021
Communications Biology

Volume: 4, P: 1-19
Increased talin–vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections

The authors observed an increase of talin-vinculin spatial proximities in the livers of spotted fever Rickettsia australis or Ebola virus-infected mice when compared to mock mice. Furthermore, using EPAC1 knockout mice, they found that deletion of EPAC1 suppresses the formation of spatial proximal complex of talin-vinculin in rickettsial infections.

Yakun Liu
Jie Xiao
Bin Gong
Research01 Apr 2020
Laboratory Investigation

Volume: 100, P: 1030-1041
Author Correction: Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection

Fei Li
Diping Song
Daniel S. W. Ting
Amendments and CorrectionsOpen Access22 Mar 2022
npj Digital Medicine

Volume: 5, P: 1

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