Nature Search

An online interpretable machine learning model for predicting cardiometabolic multimorbidity risk in patients with type 2 diabetes mellitus

Xiaohan Liu
Cheng Li
Jianzhong Zheng
ResearchOpen Access21 Jan 2026
Scientific Reports

Volume: 16, P: 1-18
DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning

A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

Daya Guo
Dejian Yang
Zhen Zhang
ResearchOpen Access17 Sept 2025
Nature

Volume: 645, P: 633-638
Identifying potential risk genes for clear cell renal cell carcinoma with deep reinforcement learning

The genetic risk of clear cell renal cell carcinoma is complex and the genes related are unclear. Here, the authors propose a deep reinforcement based model to identify risk genes.

Dazhi Lu
Yan Zheng
Jiajie Peng
ResearchOpen Access15 Apr 2025
Nature Communications

Volume: 16, P: 1-18
A comprehensive transformer-based approach for high-accuracy gas adsorption predictions in metal-organic frameworks

Three-dimensional representation learning is efficient in material science. Here, authors proposed a transformer-based framework for multi-purpose gas adsorption prediction. Predicted values correspond with the outcomes of adsorption experiments.

Jingqi Wang
Jiapeng Liu
Diannan Lu
ResearchOpen Access01 Mar 2024
Nature Communications

Volume: 15, P: 1-14
Cascaded deep learning for flame detection and heat release rate quantification in fire safety

Shiqiang Deng
Shuping Jiang
Jianzhong Chen
ResearchOpen Access24 Oct 2025
Scientific Reports

Volume: 15, P: 1-14
Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study

Here, the authors use data from the Adolescent Brain Cognitive Development study to show how individual variation in cognition, personality and mental health can be predicted by shared and unique brain network features.

Jianzhong Chen
Angela Tam
B. T. Thomas Yeo
ResearchOpen Access25 Apr 2022
Nature Communications

Volume: 13, P: 1-17
Exploring deep learning strategies for intervertebral disc herniation detection on veterinary MRI

Shoujin Huang
Guoxiong Deng
Mengye Lyu
ResearchOpen Access19 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery

Jianzhong Ai
Jia Li
Guangping Gao
ResearchOpen Access09 Jan 2017
Scientific Reports

Volume: 7, P: 1-6
Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development

The pathobiology of heart failure (HF) is incompletely understood. The authors identify 37 circulating proteins and 5 protein modules associated with HF risk, with several demonstrating causal effects on HF, risk factors, or cardiac dysfunction by Mendelian randomization analysis.

Amil M. Shah
Peder L. Myhre
Bing Yu
ResearchOpen Access15 Jan 2024
Nature Communications

Volume: 15, P: 1-18
Associations between the dietary inflammatory index and urinary incontinence among women younger than 65 years

Shiyu Zhang
Haiyang Bian
Qiang Wei
ResearchOpen Access29 Apr 2021
Scientific Reports

Volume: 11, P: 1-5
Enhancement of HIFU ablation by sonosensitizer-loading liquid fluorocarbon nanoparticles with pre-targeting in a mouse model

Yong Zhang
Lijun Yong
Jianzhong Zou
ResearchOpen Access06 May 2019
Scientific Reports

Volume: 9, P: 1-18
rAAV-based and intraprostatically delivered miR-34a therapeutics for efficient inhibition of prostate cancer progression

Jianzhong Ai
Jia Li
Guangping Gao
Research06 Jul 2021
Gene Therapy

Volume: 29, P: 418-424
Synergistic targeting strategies for prostate cancer

In this Review, the authors discuss current immunotherapy, targeted therapy and gene therapy and propose a synergistic model of combination therapy for prostate cancer, which could enhance the effectiveness of these treatments.

Xuanji Li
Zeyu Han
Jianzhong Ai
Reviews20 May 2025
Nature Reviews Urology

Volume: 22, P: 645-671
The prognostic significance of Albumin-to-Alkaline Phosphatase Ratio in upper tract urothelial carcinoma

Ping Tan
Nan Xie
Qiang Wei
ResearchOpen Access17 Aug 2018
Scientific Reports

Volume: 8, P: 1-8
Seismic behaviour analysis of a wind turbine tower affected by sea ice based on a simplified model

Shuai Huang
Qingjie Qi
Jianzhong Liu
ResearchOpen Access24 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Hybrid DWT NLM method with NOA optimization for ECG signal denoising

Wen Chen
Yuanfang Zhang
Jianzhong Hao
ResearchOpen Access07 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Comprehensive discovery and functional characterization of the noncanonical proteome

Chengyu Shi
Fangzhou Liu
Aifu Lin
ResearchOpen Access10 Jan 2025
Cell Research

Volume: 35, P: 186-204
Diff5T: Benchmarking human brain diffusion MRI with an extensive 5.0 Tesla k-space and spatial dataset

Shanshan Wang
Shoujun Yu
Hairong Zheng
ResearchOpen Access04 Aug 2025
Scientific Data

Volume: 12, P: 1-11
HematoPorphyrin Monomethyl Ether polymer contrast agent for ultrasound/photoacoustic dual-modality imaging-guided synergistic high intensity focused ultrasound (HIFU) therapy

Sijing Yan
Min LU
Jianzhong Zou
ResearchOpen Access18 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
SR9009 inhibits lethal prostate cancer subtype 1 by regulating the LXRα/FOXM1 pathway independently of REV-ERBs

Hang Xu
Jiapeng Zhang
Lu Yang
ResearchOpen Access10 Nov 2022
Cell Death & Disease

Volume: 13, P: 1-14
Large-area magnetic skin for multi-point and multi-scale tactile sensing with super-resolution

Hao Hu
Chengqian Zhang
Peng Zhao
ResearchOpen Access18 Jul 2024
npj Flexible Electronics

Volume: 8, P: 1-12
STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation

Jianzhong Li
Youjing Yang
Shasha Tao
ResearchOpen Access19 Jan 2022
Cell Death & Disease

Volume: 13, P: 1-11
Biochemical evolution of dissolved organic matter during snow metamorphism across the ablation season for a glacier on the central Tibetan Plateau

Lin Feng
Yanqing An
Yuhong Liao
ResearchOpen Access09 Apr 2020
Scientific Reports

Volume: 10, P: 1-10
Reduced osteoclast-derived apoptotic bodies in bone marrow characterizes the pathological progression of osteoporosis

Yutong Wu
Hongbo Ai
Fei Luo
ResearchOpen Access26 Apr 2023
Cell Death Discovery

Volume: 9, P: 1-9
Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma

Yiyi Xi
Yuan Lin
Dongxin Lin
ResearchOpen Access25 Feb 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-13
Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets

Xingpeng Di
Xiaoshuai Gao
Deyi Luo
ReviewsOpen Access31 Jul 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-32

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