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The first outbreaks of mpox outside Africa in 2022 were caused by clade II but cases of a new clade Ib have been increasing in the Democratic Republic of Congo and neighbouring countries since 2024. Here, the authors describe a case report and public health investigation of the first detected case of mpox clade Ib in China.

Sun et al. reveal that root-knot nematode attack activates a phyB-HY5 cascade that integrates light and GLR3.5-CaM2 signals to boost JA synthesis in tomato, with HY5 moving from leaves to roots to sustain signaling and trigger JA-mediated defense.

Single-beam optical pulling is counterintuitive and attractive, but to date its pulling range has been less than 0.2 mm. Here the authors demonstrate a 40-cm-long optical pulling of a droplet along a nanofibre by momentum engineering of its guided mode.

A new asymmetric non-fullerene acceptor, P2EH-1V, is designed and synthesized for constructing devices demonstrating record-high efficiencies of 26.7% (certified at 26.4%) over an aperture area greater than 1 cm² in perovskite–organic tandem solar cells.

Nie et al. report a multi-site binding ligand to suppress the formation of defects and increase the structural and water stability of perovskites. Solar cells fabricated fully in air achieves an efficiency of 25.03% and retain 98.98% of the performance after aging in air for 1,584 h without encapsulation.

Solar-powered desalination is a sustainable approach to generate clean water for our society. Here, authors report lightweight, flexible, and fluidic-diode membrane-based evaporators to allow directional water transport and optimized heat localization. This Janus evaporator design enables high performance interfacial solar water evaporation, as well as hydrovoltaic applications.

The mechanical stability of interfaces in perovskite solar cells is not well understood. Chen, Wang, Wang et al. investigate the strength of the bonds between layers and the corresponding effects on the chemical and mechanical stability of perovskite solar cells.

Quasi-random nanostructures are being considered for many photon management applications but their use has been limited by their costly fabrication. Here, Smith et al. show that the quasi-random patterns on Blu-ray movie discs are already near-optimized for light-trapping applications in solar cells.

This work proposes a unique mechanism of manipulating the mode propagation for photonic switching with a brand-new split waveguide crossing, demonstrating great potential for the applications in a wide spectrum of scenarios.

Creating highly active materials that effectively harness solar spectra is essential for photocatalysis, though challenging. Here the authors introduce a novel donor-acceptor covalent organic framework with a broad absorption range of 200 nm to 900 nm, achieving efficient artificial photocatalytic amine coupling.

Amorphous phases of self-assembling molecules employed as a hole-transporting layer in inverted perovskite solar cells contribute to homogeneous perovskite film growth, resulting in a power conversion efficiency of 25.20% (certified 24.35%) for one-square-centimetre area cells.

Nf2 physically engages with focal adhesion kinase (FAK) to preferentially mediate Erk1/2 and PI3K catalytic p110 subunit/Akt signaling, regulating osteogenic lineage development, cranial bone ossification and regeneration.

Early detection and accurate diagnosis of focal liver lesions are crucial for effective treatment and prognosis. Here, the authors present a fully automated diagnostic system that leverages multi-phase CT scans and clinical features, for diagnosing liver lesions.

Yang and colleagues present a small-molecule inhibitor for ADAR1 and show that its use is therapeutically beneficial in the context of prostate cancer.

Controlling crystal growth alignment in wide bandgap low-dimensional perovskites has been a persistent challenge. Here, authors induce vertical crystal growth through the addition of chlorine to precursor solution, giving rise to a record power conversion efficiency of 9.4% for 2 eV bandgap devices.

A self-assembled monolayer of (4-(7H-dibenzo[c,g]carbazol-7-yl)butyl)phosphonic acid is integrated in wide-bandgap perovskite solar cells, which enables a high power conversion efficiency and low open-circuit voltage deficiency, as well as efficient centimetre-scale all-perovskite tandem solar cells.

Collecting water directly from air provides one sustainable solution to water scarcity. Li et al. combine sorption-based atmospheric water harvesting with a thermoelectric module for efficient harvesting water and electricity in arid environments and show that the two components operate synergistically.

Asymmetric catalysts show promise for CO₂ electrochemical catalytic reduction. Here, the authors develop a pulsed discharge method to prepare graphene-aerogel-supported asymmetric Cu nanoclusters catalysts that enhance electrochemical CO₂ conversion into multicarbon products.

Muons are conventionally produced from cosmic rays or with a proton accelerator. Now a proof-of-principle experiment demonstrates the feasibility of muon production with a laser-driven electron beam with gigaelectronvolt energy in a lead converter target.

Function and mechanism underlying m⁶A modifications in myoblast differentiation and skeletal muscle regeneration while elucidating the regulatory role of METTL3 in promoting successful myoblast fusion.

Here, the authors explore how Ni single-atom sites on carbon nitride evolve under photocatalytic conditions. They show that this evolution plays a pivotal role in enhancing photocatalytic H₂O₂ production.

The gut-microbiota-derived aromatic amino acid metabolite 4-hydroxyphenylacetic acid (4HPAA) and its analogues have been shown to protect against obesity. In mice, 4HPAA exerts anti-obesogenic effects by modulating mucosal immunity and lipid uptake in the intestine.

Suraxavir marboxil, an antiviral drug designed to inhibit the polymerase acidic protein of influenza, alleviates symptoms in individuals with influenza faster than placebo in a phase 3 trial conducted in China.

Crystal structures of cyanobacterial protochlorophyllide oxidoreductases reveal the basis of the photocatalytic activities of this enzyme, through the role of its active site in enabling the light-driven reduction of protochlorophyllide.

Staphylococcus capitis is a common causative agent of bloodstream infections in neonatal intensive care units, with multidrug resistant isolates complicating treatment. Authors aimed to establish a core genome multilocus sequence typing (cgMLST) scheme to document the transmission and dissemination of multidrug-resistant S. capitis isolates.

To optimize the interfacial quality and electrode magnetism in spintronic devices, the authors develop an electrode transfer technique that can greatly improve device interfacial quality, performance and reproducibility, universal to various spacers.

A large light-receiving angle in planar solar cells is crucial for flexible installation of distributed photovoltaics. Here, authors report sequential-processed all-polymer solar cells with nano-sized phase separation integrated in micro-sized surface topology and maximum efficiency of over 19%.

A method is reported that produces highly strong, tough and elastic 2D COF films, using a sacrificial go-between, which endows them with new properties, enhances their current applications and paves the way for new applications.

A benchmarking competition improves tools that predict how regulatory regions control gene expression.

TGR5 activation improves myocardial lipid accumulation and cardiac dysfunction in diabetic mice, offering promise for managing diabetic cardiomyopathy.

Polo-like kinase 3 (Plk3) has a tumor suppressive role through the induction of apoptosis, however, the mechanism underlying its activation is unclear. Here, in pancreatic cancer, the authors show that activation of Plk3 is dependent on its cleavage into p41Plk3, by the metalloendopeptidase nardilysin.

High-resolution single-photon imaging is challenging due to complex hardware and noise disturbances. Here, the authors realise simultaneous single-photon denoising and super-resolution enhancement by physics-informed deep learning, with a physical multi-source noise model, two single-photon image datasets, and a deep transformer network.

Cui, Guo, Liu et al. identify a bacterial species, Peptostreptococcus anaerobius, in the gut that produces a tryptophan metabolite and engages intracellular pathways to modulate ferroptosis-suppressor protein 1 activity, thereby suppressing ferroptosis and promoting colorectal cancer development.

The formation of coacervates through phase separation of oppositely charged polyelectrolytes (PEs) is critical for understanding biological condensates and developing responsive materials. Here the authors find that oppositely charged PEs form a percolated network even in semi-dilute solutions.