Nature Search

Association between blood-brain barrier permeability and changes in pulse wave velocity following a recent small subcortical infarct

Luis Mena Romo
Juan José Mengual
Manuel Gómez-Choco
Research28 Jun 2024
Hypertension Research

Volume: 47, P: 2495-2502
Social media and smartphone app use predicts maintenance of physical activity during Covid-19 enforced isolation in psychiatric outpatients

Agnes Norbury
Shelley H. Liu
M. Mercedes Perez-Rodriguez
Research14 Dec 2020
Molecular Psychiatry

Volume: 26, P: 3920-3930
Relationship between premature loss of primary teeth with oral hygiene, consumption of soft drinks, dental care and previous caries experience

Sandra Aremy López-Gómez
Juan José Villalobos-Rodelo
Carlo Eduardo Medina-Solís
ResearchOpen Access26 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Ongoing harlequin toad declines suggest the amphibian extinction crisis is still an emergency

The status of the harlequin toads has not improved since 2004 despite species rediscoveries accompanied by increasing conservation efforts, and habitat destruction and degradation continue to threaten them today, according to an analysis of population status records over the period 2004–2022.

Stefan Lötters
Amadeus Plewnia
Enrique La Marca
ResearchOpen Access11 Nov 2023
Communications Earth & Environment

Volume: 4, P: 1-8
Multimodal cell atlas of the ageing human skeletal muscle

The Human Muscle Ageing Cell Atlas provides a series of integrated cellular and molecular explanations for sarcopenia and frailty development in advanced ages.

Yiwei Lai
Ignacio Ramírez-Pardo
Miguel A. Esteban
ResearchOpen Access22 Apr 2024
Nature

Volume: 629, P: 154-164
Subclassification of obesity for precision prediction of cardiometabolic diseases

A precision medicine approach used unsupervised clustering to identify five distinct phenotypic profiles that can better predict risks of cardiometabolic disease compared with those ascertained based on the additive value of body mass index and other biomarkers, and validated these findings across four independent cohorts.

Daniel E. Coral
Femke Smit
Paul W. Franks
ResearchOpen Access24 Oct 2024
Nature Medicine

Volume: 31, P: 534-543
Central nicotine induces browning through hypothalamic κ opioid receptor

Nicotine reduces food intake and increases energy expenditure in brown adipose tissue. Here the authors show that nicotine also induces white adipose tissue browning via central kappa opioid receptor action.

Patricia Seoane-Collazo
Laura Liñares-Pose
Miguel López
ResearchOpen Access06 Sept 2019
Nature Communications

Volume: 10, P: 1-12
An amphioxus neurula stage cell atlas supports a complex scenario for the emergence of vertebrate head mesoderm

The evolution of the vertebrate head mesoderm involved the emergence of new structures and cell types. Here the authors generated a cell atlas of the cephalochordate neurula to study the origins of these novelties and propose a revised scenario for the evolution of the vertebrate head muscles.

Xavier Grau-Bové
Lucie Subirana
Hector Escriva
ResearchOpen Access29 May 2024
Nature Communications

Volume: 15, P: 1-18
Biased-corrected richness estimates for the Amazonian tree flora

Hans ter Steege
Paulo I. Prado
Georgia Pickavance
ResearchOpen Access23 Jun 2020
Scientific Reports

Volume: 10, P: 1-13
Size effect and scaling power-law for superelasticity in shape-memory alloys at the nanoscale

The stress-induced martensitic transformation in shape-memory alloys shows a strong size-effect on the critical stress for superelasticity.

Jose F. Gómez-Cortés
Maria L. Nó
Jose M. San Juan
Research29 May 2017
Nature Nanotechnology

Volume: 12, P: 790-796
Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations

Sebastian Moguilner
Sandra Baez
Agustin Ibanez
Amendments and CorrectionsOpen Access16 Sept 2024
Nature Medicine

Volume: 30, P: 3779
Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements

The DANIO-CODE consortium leverages a large-scale multiomic dataset to improve zebrafish genome annotation. They identify ~140,000 cis-regulatory elements throughout development and perform a comparison with the mouse regulatory landscape.

Damir Baranasic
Matthias Hörtenhuber
Ferenc Müller
ResearchOpen Access04 Jul 2022
Nature Genetics

Volume: 54, P: 1037-1050
Flow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis

Noemi Puig
Bruno Paiva
Jesús F. San Miguel
Research12 Dec 2018
Leukemia

Volume: 33, P: 1256-1267
A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma

Type 2 inflammation drives the formation of pathologic mucus in patients with asthma. Here, authors reveal a role for intelectin-1 in IL-13-induced mucus properties, and that an ITLN1 eQTL is associated with protection from the formation of mucus plugs in T2-high asthma.

Jamie L. Everman
Satria P. Sajuthi
Max A. Seibold
ResearchOpen Access09 May 2024
Nature Communications

Volume: 15, P: 1-17
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma

Multiple myeloma (MM) cancer cells can develop different resistance mechanisms to therapies inducing DNA-damage. Here, the authors show that the mitochondrial DNA repair protein DNA2 promotes MM cells survival after DNA damage-induced metabolic reprogramming.

Natthakan Thongon
Feiyang Ma
Simona Colla
ResearchOpen Access08 Feb 2024
Nature Communications

Volume: 15, P: 1-13
Long runs of homozygosity are associated with Alzheimer’s disease

Sonia Moreno-Grau
Maria Victoria Fernández
Agustín Ruiz
ResearchOpen Access24 Feb 2021
Translational Psychiatry

Volume: 11, P: 1-12
Systemic rewiring of dendritic cells by melanoma-secreted midkine impairs immune surveillance and response to immune checkpoint blockade

Catena et al. report that melanoma-secreted midkine impairs differentiation and function of dendritic cells, limiting antitumor immunity and response to immune checkpoint blockade.

Xavier Catena
Marta Contreras-Alcalde
María S. Soengas
Research28 Mar 2025
Nature Cancer

Volume: 6, P: 682-701
Telomere-based risk models for the early diagnosis of clinically significant prostate cancer

Juan Manuel Rubio Galisteo
Luis Fernández
Pilar Najarro
ResearchOpen Access04 May 2020
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 88-95
Role of the 4Kscore test as a predictor of reclassification in prostate cancer active surveillance

Ángel Borque-Fernando
José Rubio-Briones
David Okrongly
Research14 Aug 2018
Prostate Cancer and Prostatic Diseases

Volume: 22, P: 84-90
Prediction of survival in patients with advanced, refractory colorectal cancer in treatment with trifluridine/tipiracil: real-world vs clinical trial data

Ana Fernández Montes
Alberto Carmona-Bayonas
Teresa Garcia García
ResearchOpen Access12 Jul 2021
Scientific Reports

Volume: 11, P: 1-10
Evolution of a histone variant involved in compartmental regulation of NAD metabolism

MacroH2A histone variants originated before the split of fungi and animals. ADP-ribose binding is an ancestral feature of their macrodomains and is linked to the compartmental regulation of NAD metabolism. This function was selected for during the evolution of metazoans.

Iva Guberovic
Sarah Hurtado-Bagès
Marcus Buschbeck
Research09 Dec 2021
Nature Structural & Molecular Biology

Volume: 28, P: 1009-1019
Meta-analysis of genome-wide association studies for cancer therapy-related cardiovascular dysfunction and functional mapping highlight an intergenic region close to TP63

L. Martínez-Campelo
A. Blanco-Verea
Juan Quiles
ResearchOpen Access08 Aug 2024
Scientific Reports

Volume: 14, P: 1-10
Amphioxus functional genomics and the origins of vertebrate gene regulation

Genomic, epigenomic and transcriptomic data derived from the Mediterranean amphioxus (Branchiostoma lanceolatum) provide insights into the evolution of the genomic regulatory landscape of chordates.

Ferdinand Marlétaz
Panos N. Firbas
Manuel Irimia
ResearchOpen Access21 Nov 2018
Nature

Volume: 564, P: 64-70
Electrical stimulation for erectile dysfunction: a systematic review and meta-analysis of RCTs

Álvaro Navas Mosqueda
Giuseppe Maiolino
Esaú Fernández-Pascual
Reviews07 Oct 2025
International Journal of Impotence Research

P: 1-10
γ-Linolenic acid in maternal milk drives cardiac metabolic maturation

The switch from glucose- to fatty acid-dependent metabolism in cardiomyocytes of newborn mice is governed by γ-linolenic acid in maternal milk, which binds to retinoid X receptors, thereby causing a transcription-dependent metabolic transition.

Ana Paredes
Raquel Justo-Méndez
Mercedes Ricote
Research24 May 2023
Nature

Volume: 618, P: 365-373
Pre-engraftment cytomegalovirus DNAemia in allogeneic hematopoietic stem cell transplant recipients: incidence, risk factors, and clinical outcomes

Carlos Solano
Estela Giménez
David Navarro
Research13 Jun 2018
Bone Marrow Transplantation

Volume: 54, P: 90-98
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

Jorge Ferrer and colleagues have mapped regulatory SNP variants associated in GWAS with type 2 diabetes risk and glycemic traits to large clusters of enhancer elements regulating the transcriptional identity of pancreatic β cells via a highly connected transcription factor network.

Lorenzo Pasquali
Kyle J Gaulton
Jorge Ferrer
Research12 Jan 2014
Nature Genetics

Volume: 46, P: 136-143
Discovery of X-ray polarization angle rotation in the jet from blazar Mrk 421

In June 2022, the IXPE satellite observed a shock passing through the jet of active galaxy Markarian 421. The rotation of the X-ray-polarized radiation over a 5-day period revealed that the jet contains a helical magnetic field.

Laura Di Gesu
Herman L. Marshall
Silvia Zane
Research17 Jul 2023
Nature Astronomy

Volume: 7, P: 1245-1258
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis

SFRP1, an ADAM10 inhibitor, is elevated in the brains of patients with Alzheimer’s disease (AD). Antibody-mediated neutralization of its activity stalls brain alterations and cognitive loss in AD-like mice, supporting SFRP1 as a potential target for disease therapy.

Pilar Esteve
Javier Rueda-Carrasco
Paola Bovolenta
Research15 Jul 2019
Nature Neuroscience

Volume: 22, P: 1258-1268
Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis

The transcriptional regulation of morphogenetic effectors during eye development is poorly understood. Here, the authors show that transcription of an endocytosis regulator Opois crucial for the neural retina development in zebrafish and activated by the interaction of the transcription factor Vsx2 and retinal enhancer H6_10137.

Ines Gago-Rodrigues
Ana Fernández-Miñán
Juan R. Martinez-Morales
Research12 May 2015
Nature Communications

Volume: 6, P: 1-13
Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

Blood brain barrier (BBB) opening is being investigated as a therapeutic approach for neurodegenerative diseases. Here, the authors report the results of a phase I trial to evaluate the feasibility and safety of BBB opening of the right parieto-occipito-temporal cortex in Parkinson´s disease with dementia.

Carmen Gasca-Salas
Beatriz Fernández-Rodríguez
José A. Obeso
ResearchOpen Access03 Feb 2021
Nature Communications

Volume: 12, P: 1-7
Author Correction: Subclassification of obesity for precision prediction of cardiometabolic diseases

Daniel E. Coral
Femke Smit
Paul W. Franks
Amendments and CorrectionsOpen Access21 Nov 2024
Nature Medicine

Volume: 31, P: 695
Dapagliflozin and short-term changes on circulating antigen carbohydrate 125 in heart failure with reduced ejection fraction

Martina Amiguet
Patricia Palau
Julio Núñez
ResearchOpen Access30 Jun 2023
Scientific Reports

Volume: 13, P: 1-7
A Spanish-Portuguese GWAS of progressive supranuclear palsy reveals a novel risk locus in NFASC

Pablo García-González
Héctor Rodrigo Lara
Agustín Ruiz
Research16 May 2025
European Journal of Human Genetics

Volume: 33, P: 960-965
Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved

Analysis of the results of a large clinical trial, EMPEROR-Preserved, shows that the SGLT2 inhibitor empagliflozin improves outcomes for heart failure patients with either mid-range (41–49%) or preserved (≥50%) ejection fraction, supporting the use of this drug for both categories of patients.

Stefan D. Anker
Javed Butler
Faiez Zannad
ResearchOpen Access05 Dec 2022
Nature Medicine

Volume: 28, P: 2512-2520
A comparative analysis of collagen based dressings and polysaccharide microspheres for hemostasis management in hepatic stab wounds

Francisco José Sánchez del Valle
María Isabel Sánchez-Seco
Juan Garófano
ResearchOpen Access30 Jan 2025
Scientific Reports

Volume: 15, P: 1-7
Students caught up in legal impasse at Mexican institute

Aarón Morelos Gómez
Eduardo Gracia Espino
Juan Carlos García Gallegos
Correspondence14 Apr 2010
Nature

Volume: 464, P: 977
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Differential responses of Miocene rodent metacommunities to global climatic changes were mediated by environmental context

Fernando Blanco
Ana Rosa Gómez Cano
Manuel Hernández Fernández
ResearchOpen Access06 Feb 2018
Scientific Reports

Volume: 8, P: 1-12
The paradox of haematopoietic cell transplant in Latin America

Gregorio Jaimovich
Robert Peter Gale
Juliana Martinez Rolón
Research13 May 2021
Bone Marrow Transplantation

Volume: 56, P: 2382-2388
Characterisation of the blood RNA host response underpinning severity in COVID-19 patients

Heather Jackson
Irene Rivero Calle
Calviño-Suárez Cristina
ResearchOpen Access17 Jul 2022
Scientific Reports

Volume: 12, P: 1-14
Fluorescent bicolour sensor for low-background neutrinoless double β decay experiments

A fluorescent bicolour sensor is proposed as the basis of a barium-tagging technique for the detection of neutrinoless double β decay in xenon gas experiments.

Iván Rivilla
Borja Aparicio
Juan J. Gómez-Cadenas
Research22 Jun 2020
Nature

Volume: 583, P: 48-54
Low-temperature hydroformylation of ethylene by phosphorous stabilized Rh sites in a one-pot synthesized Rh-(O)-P-MFI zeolite

Isolated Rh³⁺ sites are stabilized inside the MFI zeolite channels with phosphorous which is added during zeolite synthesis in the form of a phosphonium zeolite template. This Rh³⁺ shows high activity in the low-temperature ethylene hydroformylation.

Minjie Zhao
Chengeng Li
Avelino Corma
ResearchOpen Access07 Nov 2023
Nature Communications

Volume: 14, P: 1-13
The cognitive and psychiatric subacute impairment in severe Covid-19

Pedro J. Serrano-Castro
Francisco J. Garzón-Maldonado
Fernando Rodríguez de Fonseca
ResearchOpen Access03 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
Reversal of cerebral pseudoatrophy in normal pressure hydrocephalus after ventriculoatrial shunt placement

Andrés Segura-Hernández
Diego F. Gómez-Amarillo
Fernando Hakim
ResearchOpen Access10 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region

Susceptibility to asthma and severity of symptoms are regulated by a number of different genomic regions. Here the authors characterise a 5kb regulatory region and demonstrate genetic and topological regulation of IL33 and association with disease in different human cohorts.

Ivy Aneas
Donna C. Decker
Marcelo A. Nóbrega
ResearchOpen Access21 Oct 2021
Nature Communications

Volume: 12, P: 1-12
Choroid plexus volume is enlarged in long COVID and associated with cognitive and brain changes

Maria Diez-Cirarda
Miguel Yus-Fuertes
Jordi A. Matias-Guiu
ResearchOpen Access15 Jan 2025
Molecular Psychiatry

Volume: 30, P: 2821-2830
The phylogenetic roots of human lethal violence

The percentage of human deaths caused by interpersonal violence reflects our membership of a particularly violent clade of mammals, although changes in socio-political organization have led to marked variations in this proportion.

José María Gómez
Miguel Verdú
Marcos Méndez
Research28 Sept 2016
Nature

Volume: 538, P: 233-237
DNA methylome biomarkers of rheumatoid arthritis-associated interstitial lung disease reflecting lung fibrosis pathways, an exploratory case–control study

Bartosz Kaczmarczyk
Carlos de la Calle-Fabregat
Susana Holgado
ResearchOpen Access29 Apr 2025
Scientific Reports

Volume: 15, P: 1-12
Attention and impulsivity assessment using virtual reality games

David Mendez-Encinas
Aaron Sujar
David Delgado-Gomez
ResearchOpen Access22 Aug 2023
Scientific Reports

Volume: 13, P: 1-10

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