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Scientific Reports (16)
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Showing 1–50 of 73 results

Advanced filters: Author: Juanjuan Xu Clear advanced filters

Nucleus-translocated glucokinase functions as a protein kinase to phosphorylate TAZ and promote tumour growth

Hypoxic stress remodels key cellular pathways in tumor. Here the authors identify that hypoxia induces glucokinase phosphorylation and nuclear localization, contributing to TAZ activation and tumor growth.

Gaoxiang Zhao
Shudi Luo
Zhimin Lu
ResearchOpen Access04 Aug 2025
Nature Communications

Volume: 16, P: 1-13
Helicobacter pylori antimicrobial resistance and gene variants in Shandong Province

Zhijing Xue
Qi Zhao
Guohai Su
ResearchOpen Access01 Oct 2025
Scientific Reports

Volume: 15, P: 1-12
SART3 promotes homologous recombination repair by stimulating DNA-RNA hybrids removal and DNA end resection

Transient R-loops form around DSBs must be timely removed for HR repair. Here, the authors show that SART3 promotes DDX1 helicase binding to DSBs for optimal DNA-RNA hybrid removal, and enhances USP15-BARD1 association for efficient DNA end resection.

Hui Fu
Min Huang
Caixia Guo
ResearchOpen Access06 Mar 2025
Nature Communications

Volume: 16, P: 1-18
Application-driven design of non-aqueous electrolyte solutions through quantification of interfacial reactions in lithium metal batteries

Tailored non-aqueous electrolyte solutions are formulated using data obtained from extensive analytical measurements and analyses. These optimized electrolytes improve the cycling performance of single-layer stack lithium metal pouch cells, particularly in lean electrolyte conditions.

Hansen Wang
Xiaolin Yan
Chuying Ouyang
ResearchOpen Access28 May 2025
Nature Nanotechnology

Volume: 20, P: 1034-1042
Erratum: Follicular CXCR5-expressing CD8⁺ T cells curtail chronic viral infection

Ran He
Shiyue Hou
Lilin Ye
Amendments and Corrections19 Oct 2016
Nature

Volume: 540, P: 470
Ductal lavage followed by observation versus oral corticosteroids in idiopathic granulomatous mastitis: A randomized trial

Ductal lavage represents a treatment option for idiopathic granulomatous mastitis. Here, the authors report the results of a randomized clinical trial, indicating that ductal lavage followed by observation is non-inferior to oral corticosteroids

Xiaolin Chen
Heng Huang
Kai Chen
ResearchOpen Access23 Oct 2024
Nature Communications

Volume: 15, P: 1-10
Author Correction: N₂ cleavage by silylene and formation of H₂Si(μ-N)₂SiH₂

Liyan Cai
Bing Xu
Xuefeng Wang
Amendments and CorrectionsOpen Access24 May 2024
Nature Communications

Volume: 15, P: 1-3
Rewiring of a KNOXI regulatory network mediated by UFO underlies the compound leaf development in Medicago truncatula

This study reveals a pathway in which the transformation of trifoliate leaves into pinnate-like pentafoliate leaves is regulated by the conserved regulators of floral development (MtUFO) and leaf development (MtKNOXI) in M. truncatula.

Zhichao Lu
Juanjuan Zhang
Chuanen Zhou
ResearchOpen Access06 Apr 2024
Nature Communications

Volume: 15, P: 1-14
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23

Jing Wang, Fengchun Zhang and colleagues report the results of a genome-wide association study of primary Sjögren's syndrome, a common autoimmune disease. They confirm associations in the STAT4, TNFAIP3 and HLA regions and identify a new susceptibility locus in the GTF2I region at 7q11.23.

Yongzhe Li
Kunlin Zhang
Fengchun Zhang
Research06 Oct 2013
Nature Genetics

Volume: 45, P: 1361-1365
METTL3-dependent m⁶A modification programs T follicular helper cell differentiation

T follicular helper (T_FH) cells are specialized effector CD4⁺ T cells that are critical in humoral immunity, but the function of post-transcriptional regulation is not clearly defined. Here, the authors demonstrate that RNA methylation is important for T_FH effector differentiation and subsequent antibody formation through stabilization of Tcf7 transcripts.

Yingpeng Yao
Ying Yang
Shuyang Yu
ResearchOpen Access26 Feb 2021
Nature Communications

Volume: 12, P: 1-16
The impact of ulinastatin on lymphocyte apoptosis and autophagy in sepsis patients

Dexin Zhang
Juanjuan Song
Ying Deng
ResearchOpen Access20 Nov 2024
Scientific Reports

Volume: 14, P: 1-8
Tracking-seq reveals the heterogeneity of off-target effects in CRISPR–Cas9-mediated genome editing

The off-target effects of any CRISPR-based genome editor are identified with Tracking-seq.

Ming Zhu
Runda Xu
Xun Lan
Research02 Jul 2024
Nature Biotechnology

Volume: 43, P: 799-810
The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases

Whether the female reproductive tract harbours distinct microbiomes beyond the vagina has been a matter of debate. Here, the authors show a subject-specific continuity in microbial communities at six sites along the female reproductive tract, indicative of a non-sterile environment.

Chen Chen
Xiaolei Song
Huijue Jia
ResearchOpen Access17 Oct 2017
Nature Communications

Volume: 8, P: 1-11
Genome sequencing of ‘Fuji’ apple clonal varieties reveals genetic mechanism of the spur-type morphology

Spur-type of growth is preferred for apple production. Here, the authors employ the trio-based phasing approach to assemble a fully phased Fuji genome and reveal the association of a 167-bp deletion in the promoter region of the MdTCP11 gene with the spur-type varieties.

Yudong Cai
Xiuhua Gao
Dong Zhang
ResearchOpen Access21 Nov 2024
Nature Communications

Volume: 15, P: 1-14
Association analysis identifies new risk loci for congenital heart disease in Chinese populations

Genome-wide association studies in Chinese and Europeans have identified multiple loci associated with congenital heart disease. Here the authors use existing GWAS data to conduct an extended three-stage analysis in Han Chinese and identify four novel loci linked to disease risk in this population.

Yuan Lin
Xuejiang Guo
Zhibin Hu
Research18 Aug 2015
Nature Communications

Volume: 6, P: 1-7
Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia

Tumour cells can communicate with cells from distant organs through extracellular vesicles. Here the authors show that breast cancer cells derived exosomal miR-204-5p induce leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia.

Yong Hu
Liu Liu
Wei Yan
ResearchOpen Access24 Aug 2023
Nature Communications

Volume: 14, P: 1-20
Rational design of true monomeric and bright photoactivatable fluorescent proteins

Structure determination followed by targeted engineering of the popular photoactivatable fluorescent protein monomeric (m)Eos2 yields mEos3 versions that are more monomeric and less disruptive in protein fusions and also exhibit higher labeling density, brightness and other beneficial properties.

Mingshu Zhang
Hao Chang
Tao Xu
Research13 May 2012
Nature Methods

Volume: 9, P: 727-729
A dicarbonate solvent electrolyte for high performance 5 V-Class Lithium-based batteries

Rechargeable lithium batteries featuring 5 V cathodes offer high energy density yet struggle with stability. Here, the authors formulate an electrolyte incorporating dimethyl 2,5-dioxahexanedioate solvent, which facilitates stable lithium plating and stripping while offering an extended cycle life.

Xiaozhe Zhang
Pan Xu
Alexandru Vlad
ResearchOpen Access15 Jan 2024
Nature Communications

Volume: 15, P: 1-18
Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC

Inflammasomes are multiprotein complexes, including the protein ASC, that assemble in response to inflammatory stimulation. Here the authors characterise the regulation of ASC during inflammasome formation and show the involvement of SUMOylation and zinc-finger and BTB domain-containing protein 16 (ZBTB16).

Danfeng Dong
Yuzhang Du
Dakang Xu
ResearchOpen Access20 Dec 2023
Nature Communications

Volume: 14, P: 1-16
Programming cell-surface signaling by phase-separation-controlled compartmentalization

A membrane-tethering liquid–liquid phase-separation system was developed for programmable compartmentalization of cell-surface proteins and regulation of downstream cellular activities.

Ru Li
Tiantian Li
Pilong Li
Research17 Nov 2022
Nature Chemical Biology

Volume: 18, P: 1351-1360
N₂ cleavage by silylene and formation of H₂Si(μ-N)₂SiH₂

So far, only homoleptic N₂ complexes of silicon have been reported under matrix-isolation conditions including but the activation of more inert nitrogen by silylenes remains challenging. Here the authors report on the activation of dinitrogen by silylenes under cryogenic conditions.

Liyan Cai
Bing Xu
Xuefeng Wang
ResearchOpen Access08 May 2024
Nature Communications

Volume: 15, P: 1-10
Draft genome sequence of the mulberry tree Morus notabilis

Mulberry trees are the primary food source for silkworms, which are reared for the production of silk. In this study, He et al. present the draft genome sequence of Morus notabilisand find that it evolved significantly faster than other plants in the Rosales order.

Ningjia He
Chi Zhang
Zhonghuai Xiang
ResearchOpen Access19 Sept 2013
Nature Communications

Volume: 4, P: 1-9
Intentional corrosion-induced reconstruction of defective NiFe layered double hydroxide boosts electrocatalytic nitrate reduction to ammonia

Fe-based electrodes emerge as an effective and economical option to treat nitrate-laden wastewater. Whereas Fe cathode corrosion is commonly considered as an adverse factor for the electroreduction of nitrate to ammonia, intentional corrosion-induced surficial reconstruction has the potential to enhance catalytic performance.

Kaifeng Wang
Ran Mao
Xu Zhao
Research05 Dec 2023
Nature Water

Volume: 1, P: 1068-1078
PPARδ is a regulator of autophagy by its phosphorylation

Qian Gou
Yidan Jiang
Yongzhong Hou
Research21 May 2020
Oncogene

Volume: 39, P: 4844-4853
Seasonal pattern of influenza activity in a subtropical city, China, 2010–2015

Xu-Xiang Liu
Yahong Li
Xi-Ling Wang
ResearchOpen Access13 Dec 2017
Scientific Reports

Volume: 7, P: 1-7
Flexible asymmetric supercapacitors based on ultrathin two-dimensional nanosheets with outstanding electrochemical performance and aesthetic property

Shan Shi
Chengjun Xu
Feiyu Kang
ResearchOpen Access06 Sept 2013
Scientific Reports

Volume: 3, P: 1-8
Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial

Aijun Zhang
Kangkang Han
Huaichen Li
ResearchOpen Access23 Jan 2025
Scientific Reports

Volume: 15, P: 1-11
Aluminum nitride nanophotonics for beyond-octave soliton microcomb generation and self-referencing

Though octave soliton microcombs are attractive for on-chip metrology and optical clocks, limitations in existing materials lead to increased chip integration complexity. Here, the authors report access to octave soliton microcombs and self-referencing using aluminium nitride nanophotonic chips.

Xianwen Liu
Zheng Gong
Hong X. Tang
ResearchOpen Access14 Sept 2021
Nature Communications

Volume: 12, P: 1-7
MAPK4 inhibits the early aberrant activation of B cells in rheumatoid arthritis by promoting the IRF4-SHIP1 signaling pathway

Pei Huang
Guangli Yang
Zuochen Du
ResearchOpen Access26 Jan 2025
Cell Death & Disease

Volume: 16, P: 1-15
Use of a 6-miRNA panel to distinguish lymphoma from reactive lymphoid hyperplasia

Juanjuan Kang
Sisi Yu
Jian Huang
ResearchOpen Access03 Jan 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-3
METTL14 promotes neuroblastoma formation by inhibiting YWHAH via an m6A-YTHDF1-dependent mechanism

Jianwei Wang
Hongli Yin
Jian Pan
ResearchOpen Access22 Apr 2024
Cell Death Discovery

Volume: 10, P: 1-15
Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway

Juanjuan Han
Li-nan Zhan
Xin-an Zhang
ResearchOpen Access01 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
Follicular CXCR5-expressing CD8⁺ T cells curtail chronic viral infection

A population of partially exhausted CXCR5⁺ CD8⁺ T cells, induced by chronic virus infection and residing in B-cell follicles, is shown to control viral replication.

Ran He
Shiyue Hou
Lilin Ye
Research02 Aug 2016
Nature

Volume: 537, P: 412-416
Integrative bioinformatics and immunohistochemical analysis unravel the prognostic significance and immunological implication of LIMCH1 in breast cancer: a retrospective study

Xin Yu
Bei Li
Juanjuan Li
ResearchOpen Access09 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Parabacteroides as a promising target for disease intervention: current stage and pending issues

Jing Liu
Hui Qiu
Lin Xu
ReviewsOpen Access19 Jul 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-12
Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Single-cell transcriptome and T cell receptor analysis of bronchoalveolar lavage fluid suggests enrichment of proinflammatory macrophages in patients with severe COVID-19 and the presence of clonally expanded CD8⁺ T cells in patients with moderate COVID-19.

Mingfeng Liao
Yang Liu
Zheng Zhang
Research12 May 2020
Nature Medicine

Volume: 26, P: 842-844
B cell lymphoma 6 promotes hepatocellular carcinoma progression by inhibiting tumor infiltrating CD4⁺T cell cytotoxicity through ESM1

Jiatao Li
Juan Feng
Cheng Qian
ResearchOpen Access01 Jul 2024
npj Precision Oncology

Volume: 8, P: 1-16
One thousand plant transcriptomes and the phylogenomics of green plants

The One Thousand Plant Transcriptomes Initiative provides a robust phylogenomic framework for examining green plant evolution that comprises the transcriptomes and genomes of diverse species of green plants.

James H. Leebens-Mack
Michael S. Barker
Gane Ka-Shu Wong
ResearchOpen Access23 Oct 2019
Nature

Volume: 574, P: 679-685
Long non-coding RNA CAR10 promotes angiogenesis of lung adenocarcinoma by mediating nuclear LDHA to epigenetically regulate VEGFA/C

Long non-coding RNA CAR10 regulates post-translational modification of LDHA and increases the H3K79 methylation of VEGFA/VEGFC to promote angiogenesis of lung adenocarcinoma, which is a potential therapeutic target for lung adenocarcinoma.

Xiaolu Ge
Chao Du
Zheng Li
ResearchOpen Access09 Jan 2025
Communications Biology

Volume: 8, P: 1-14
Demyelination-derived lysophosphatidylserine promotes microglial dysfunction and neuropathology in a mouse model of Alzheimer’s disease

Yubo Zhou
Zonghui Huang
Rongbin Zhou
Research01 Jan 2025
Cellular & Molecular Immunology

Volume: 22, P: 134-149
PD-L1 degradation pathway and immunotherapy for cancer

Qian Gou
Chen Dong
Yongzhong Hou
ReviewsOpen Access06 Nov 2020
Cell Death & Disease

Volume: 11, P: 1-7
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma

Wei Xu
Linna Chen
Zheng Li
ResearchOpen Access07 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-13
Investigating the prognostic value of mTORC1 signaling in bladder cancer via bioinformatics evaluation

Xin Yu
Wenge Li
Juanjuan Li
ResearchOpen Access12 Dec 2023
Scientific Reports

Volume: 13, P: 1-15
Autophagy deficiency promotes M1 macrophage polarization to exacerbate acute liver injury via ATG5 repression during aging

Rui Liu
Juanjuan Cui
Hua Wang
ResearchOpen Access20 Dec 2021
Cell Death Discovery

Volume: 7, P: 1-14
Targeting the COX2/MET/TOPK signaling axis induces apoptosis in gefitinib-resistant NSCLC cells

Juanjuan Xiao
Fei Wang
Feng Zhu
ResearchOpen Access14 Oct 2019
Cell Death & Disease

Volume: 10, P: 1-12
Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human

Juanjuan Zhao
Shuye Zhang
Zheng Zhang
ResearchOpen Access28 Apr 2020
Cell Discovery

Volume: 6, P: 1-19
Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC

Juanjuan Xiao
Lu Zhang
Feng Zhu
ResearchOpen Access27 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-10
Association of composite dietary antioxidant index with depression and all-cause mortality in middle-aged and elderly population

Juanjuan Luo
Xiying Xu
Leiyong Zhao
ResearchOpen Access29 Apr 2024
Scientific Reports

Volume: 14, P: 1-13
Correlation analysis of disulfidptosis-related gene signatures with clinical prognosis and immunotherapy response in sarcoma

Juan Xu
Kangwen Guo
Chao Wang
ResearchOpen Access26 Mar 2024
Scientific Reports

Volume: 14, P: 1-28
Association studies of TNFSF4, TNFAIP3 and FAM167A-BLK polymorphisms with primary Sjogren’s syndrome in Han Chinese

Fei Sun
Ping Li
Fengchun Zhang
Research02 May 2013
Journal of Human Genetics

Volume: 58, P: 475-479

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