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Structural basis for the recognition and ubiquitylation of type-2 N-degron substrate by PRT1 plant N-recognin

PRT1 is an E3 ligase that recognizes type-2 hydrophobic aromatic Arg/N-degrons. Here, the authors reveal the structure of the ZZ domain of Arabidopsis PRT1 bound to bulky hydrophobic type-2 N-degrons, showing a unique binding site formed by a substantial conformational change of two loops and uncovering an intramolecular tandem RING dimer essential for its ubiquitylation activity.

Woo Seok Yang
Seu Ha Kim
Hyun Kyu Song
ResearchOpen Access21 Aug 2025
Nature Communications

Volume: 16, P: 1-14
Putting on the brakes: Bacterial impediment of wound healing

Kimberly M. Brothers
Nicholas A. Stella
Robert M. Q. Shanks
ResearchOpen Access14 Sept 2015
Scientific Reports

Volume: 5, P: 1-14
High-throughput LPS profiling as a tool for revealing of bacteriophage infection strategies

Eugene E. Kulikov
Alla K. Golomidova
Andrey V. Letarov
ResearchOpen Access27 Feb 2019
Scientific Reports

Volume: 9, P: 1-10
Analysis of behavioral flow resolves latent phenotypes

BehaviorFlow is a behavioral analysis package that overcomes challenges with multiple testing when dealing with large numbers of behavioral variables and limited availability of data. BehaviorFlow also allows combining datasets from different experiments.

Lukas M. von Ziegler
Fabienne K. Roessler
Johannes Bohacek
ResearchOpen Access12 Nov 2024
Nature Methods

Volume: 21, P: 2376-2387
Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa

Mutations in gene pmrB are found in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Here, Bricio-Moreno et al. show in a mouse model of respiratory infection that the mutations enhance bacterial adherence to epithelial cells and resistance to lysozyme, but also increase antibiotic susceptibility.

Laura Bricio-Moreno
Victoria H. Sheridan
Daniel R. Neill
ResearchOpen Access06 Jul 2018
Nature Communications

Volume: 9, P: 1-12
A NEW APPROACH IN SHOCK THERAPY DURING EARLY LIFE: Experimental study

G Hollmann
K R Koczorek
R Schadwinkel
Research01 Feb 1974
Pediatric Research

Volume: 8, P: 142
COLONIC PERFUSION STUDIES IN CONGENITAL CHLORIDE DIARRHOEA

C Holmberg
K Launiala
J Perheentupa
Research01 Feb 1974
Pediatric Research

Volume: 8, P: 142
Toward three-dimensional hybrid inorganic/organic optoelectronics based on GaN/oCVD-PEDOT structures

Though integrating functional organic materials with semiconductor nanostructures is attractive for 3D chip processing, realizing these hybrids remains a challenge. Here, the authors report an oxidative chemical vapor deposition-based process for designing novel 3D hybrid optoelectronic structures.

Linus Krieg
Florian Meierhofer
Tobias Voss
ResearchOpen Access09 Oct 2020
Nature Communications

Volume: 11, P: 1-10
Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

Naomi N. K. Kreamer
Rajiv Chopra
Tsuyoshi Uehara
ResearchOpen Access20 Sept 2018
Scientific Reports

Volume: 8, P: 1-12
Fundamentals and comprehensive insights on pulsed laser synthesis of advanced materials for diverse photo- and electrocatalytic applications

Pulsed laser method uses a laser as an energy source to produce diverse materials in various environments for the reactions of photo- and electrocatalytic applications.

Jayaraman Theerthagiri
K. Karuppasamy
Myong Yong Choi
ReviewsOpen Access10 Aug 2022
Light: Science & Applications

Volume: 11, P: 1-47
From eDNA to decisions using a multi-method approach to restoration planning in streams

A. J. Adams
C. Kamoroff
C. S. Goldberg
ResearchOpen Access21 Jun 2024
Scientific Reports

Volume: 14, P: 1-11

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Structural basis for the recognition and ubiquitylation of type-2 N-degron substrate by PRT1 plant N-recognin

Putting on the brakes: Bacterial impediment of wound healing

High-throughput LPS profiling as a tool for revealing of bacteriophage infection strategies

Analysis of behavioral flow resolves latent phenotypes

Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa

A NEW APPROACH IN SHOCK THERAPY DURING EARLY LIFE: Experimental study

COLONIC PERFUSION STUDIES IN CONGENITAL CHLORIDE DIARRHOEA

Toward three-dimensional hybrid inorganic/organic optoelectronics based on GaN/oCVD-PEDOT structures

Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

Fundamentals and comprehensive insights on pulsed laser synthesis of advanced materials for diverse photo- and electrocatalytic applications

From eDNA to decisions using a multi-method approach to restoration planning in streams

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