Iron–sulfur clusters are important cofactors involved in a wide range of protein functions, however, the incorporation of FeS clusters into proteins remains underexplored. Here, the authors report the crystal structure of a Zn-containing form of a Rieske protein, in which ZnCl2 binds in an FeS-binding site, representing a putative immature form of a Rieske protein prior to FeS insertion.
- Erika Tsutsumi
- Satomi Niwa
- Kazuki Takeda