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Efficacy and safety of combination immunotherapy for treating advanced non-clear cell renal cell carcinoma: A multicenter retrospective study in Japan

Koji Iinuma
Yuta Sano
Takuya Koie
ResearchOpen Access10 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
Genome sequencing provides high diagnostic yield and new etiological insights for intellectual disability and developmental delay

Kohei Hamanaka
Atsushi Fujita
Naomichi Matsumoto
ResearchOpen Access26 Aug 2025
npj Genomic Medicine

Volume: 10, P: 1-12
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence

The epigenetic mark H3K9me3 is associated with silencing of lineage-inappropriate genes. Here the authors show that some lineage-inappropriate genes are derepressed in senescent cells through physical decompaction of H3K9me3-heterochromatic regions.

Kosuke Tomimatsu
Dóra Bihary
Masashi Narita
Research23 Dec 2021
Nature Aging

Volume: 2, P: 31-45
Subclinical nephrosclerosis is linked to left ventricular hypertrophy independent of classical atherogenic factors

Naoki Haruyama
Akihiro Tsuchimoto
Takanari Kitazono
Research05 Dec 2013
Hypertension Research

Volume: 37, P: 472-477
Machine learning evaluation of intensified conditioning on haematopoietic stem cell transplantation in adult acute lymphoblastic leukemia patients

Jo, Inoue et al. use a machine-learning Bayesian causal forest algorithm to evaluate the effect of intensified myeloablative conditioning (MAC) on mortality following haematopoietic stem cell transplantation (HSCT). Intensified myeloablative conditioning (MAC) has heterogeneous effects on reducing mortality.

Tomoyasu Jo
Kosuke Inoue
Yasuyuki Arai
ResearchOpen Access25 Nov 2024
Communications Medicine

Volume: 4, P: 1-8
Identification and characterization of mutations responsible for the β-lactam resistance in oxacillin-susceptible mecA-positive Staphylococcus aureus

Tanit Boonsiri
Shinya Watanabe
Longzhu Cui
ResearchOpen Access09 Oct 2020
Scientific Reports

Volume: 10, P: 1-22
Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels

Youichi Sato
Atsushi Tajima
Teruaki Iwamoto
Research27 Apr 2020
Journal of Human Genetics

Volume: 65, P: 683-691
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17
Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma

Kosuke Higuchi
Shinichi Sakamoto
Naohiko Anzai
ResearchOpen Access20 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
An evidence review project for food with function claims ~Challenges of the Japan society for vascular failure for the promotion of adequate evidences for food with function claims

Chisa Matsumoto
Hirofumi Tomiyama
Koichi Node
Comments & Opinion31 Oct 2023
Hypertension Research

Volume: 47, P: 533-536
Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

Lizhu Yang
Kaoru Fujinami
Yasuhiro Murakawa
ResearchOpen Access26 Mar 2020
Scientific Reports

Volume: 10, P: 1-10

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Efficacy and safety of combination immunotherapy for treating advanced non-clear cell renal cell carcinoma: A multicenter retrospective study in Japan

Genome sequencing provides high diagnostic yield and new etiological insights for intellectual disability and developmental delay

Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Locus-specific induction of gene expression from heterochromatin loci during cellular senescence

Subclinical nephrosclerosis is linked to left ventricular hypertrophy independent of classical atherogenic factors

Machine learning evaluation of intensified conditioning on haematopoietic stem cell transplantation in adult acute lymphoblastic leukemia patients

Identification and characterization of mutations responsible for the β-lactam resistance in oxacillin-susceptible mecA-positive Staphylococcus aureus

Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels

Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma

An evidence review project for food with function claims ~Challenges of the Japan society for vascular failure for the promotion of adequate evidences for food with function claims

Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

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