Nature Search

Abnormal activation of platelets and inflammation in smoking-induced rheumatoid arthritis is alleviated by 3,3′-diindolylmethane

Bo Cai
Yizheng You
Du Hongyan
Research11 Oct 2025
Genes & Immunity

P: 1-13
Ultrasound-activated piezoelectric nanostickers for neural stem cell therapy of traumatic brain injury

Ultrasound-induced differentiation of neural stem cells into neurons using piezoelectric nanostickers achieves injury repair and effective restoration of physiological functions of rats with traumatic brain injury.

Wenhan Wang
Keyi Li
Jichuan Qiu
Research06 May 2025
Nature Materials

Volume: 24, P: 1137-1150
Agricultural machinery could contribute 20% of total carbon and air pollutant emissions by 2050 and compromise carbon neutrality targets in China

China’s agricultural sector continues to mechanize, but this could generate up to one-fifth of future carbon dioxide, particulate matter and nitrogen emissions. Renewable energy sources could mitigate two-thirds of these emissions.

Minghao Zhuang
Xu Wang
Xi Lu
Research24 Apr 2025
Nature Food

Volume: 6, P: 513-522
Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress

Despite common use as a diabetes mellitus supplement, chromium(III)’s pharmacological effects remain unknown. We identified the Cr(III)-proteome in cells with a metalloproteomic approach and uncovered ATP synthase as a vital target to relieve hyperglycaemia stress.

Haibo Wang
Ligang Hu
Hongzhe Sun
ResearchOpen Access28 Mar 2023
Nature Communications

Volume: 14, P: 1-15
Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans

Wang et al. profile age-dependent miRNAomic changes in worm tissues and extracellular vesicles (EVs). They show that ageing controls miRNAs in a tissue-specific manner and their findings further suggest a complex EV-mediated miRNA trafficking network across tissues.

Xueqing Wang
Quanlong Jiang
Yidong Shen
ResearchOpen Access01 Feb 2024
Nature Communications

Volume: 15, P: 1-16
DNA methylation profiling to determine the primary sites of metastatic cancers using formalin-fixed paraffin-embedded tissues

Molecular tests that can determine the tissue of origin of cancers of unknown primary (CUP) are still needed. Here, the authors develop a DNA methylation profiling assay and a machine learning classifier to predict the origin of metastatic tumours in CUP patients using formalin-fixed, paraffin embedded samples.

Shirong Zhang
Shutao He
Hongcang Gu
ResearchOpen Access14 Sept 2023
Nature Communications

Volume: 14, P: 1-11
Virtual elastography ultrasound via generative adversarial network for breast cancer diagnosis

The current use of elastography ultrasound faces challenges, including vulnerability to subjective manipulation, echo signal attenuation, unknown risks of elastic pressure and high imaging hardware cost. Here, the author shows a virtual elastography to empower low-end ultrasound devices with state-of-art elastography function.

Zhao Yao
Ting Luo
JianQiao Zhou
ResearchOpen Access11 Feb 2023
Nature Communications

Volume: 14, P: 1-12
Negative mixing enthalpy solid solutions deliver high strength and ductility

A HfNbTiVAl₁₀ alloy shows tensile ductility and ultrahigh yield strength from the addition of aluminium to a HfNbTiV alloy, resulting in a negative mixing enthalpy solid solution, which promotes strength and favours formation of hierarchical chemical fluctuations.

Zibing An
Ang Li
Xiaodong Han
Research03 Jan 2024
Nature

Volume: 625, P: 697-702
Telomeric TERB1–TRF1 interaction is crucial for male meiosis

Disrupting the interaction between telomere protein TRF1 with meiosis-specific protein TERB1 impairs the pairing of X and Y chromosomes via their telomere-adjacent pseudoautosomal regions in pachytene, leading to spermatocyte apoptosis and male infertility in mice.

Juanjuan Long
Chenhui Huang
Ming Lei
Research30 Oct 2017
Nature Structural & Molecular Biology

Volume: 24, P: 1073-1080
Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation

The role of DNA methylation in early embryo development has been difficult to determine due to the functional redundancy of DNA methyltransferases. Here they develop an efficient base editing system that enables one-step generation of Dnmt-null embryos and show that DNA methylation-related miRNA suppression may be involved in gastrulation.

Qing Li
Jiansen Lu
Jinsong Li
ResearchOpen Access22 May 2023
Nature Communications

Volume: 14, P: 1-19
Development of self-control in children aged 3 to 9 years: Perspective from a dual-systems model

Ting Tao
Ligang Wang
Wenbin Gao
ResearchOpen Access11 Dec 2014
Scientific Reports

Volume: 4, P: 1-5
YTHDF2 destabilizes m⁶A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

The YTHDF family of proteins are able to bind and regulate the stability of methylated N6 RNA. Here the authors show that this decreased m⁶A RNA stability is mediated by direct recruitment of the CCR4–NOT deadenylase complex through YTHDF proteins.

Hao Du
Ya Zhao
Ligang Wu
ResearchOpen Access25 Aug 2016
Nature Communications

Volume: 7, P: 1-11
Statistical analysis of mutant allele frequency level of circulating cell-free DNA and blood cells in healthy individuals

Ligang Xia
Zhoufang Li
Jiankui He
ResearchOpen Access08 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Super square carbon nanotube network: a new promising water desalination membrane

Ligang Sun
Xiaoqiao He
Jian Lu
ResearchOpen Access22 Apr 2016
npj Computational Materials

Volume: 2, P: 1-7
Frame points attention convolution for deep learning on point cloud

Luyang Li
Ligang He
Xie Han
ResearchOpen Access23 Apr 2025
Scientific Reports

Volume: 15, P: 1-21
Global profiling of RNA-binding protein target sites by LACE-seq

Xue and colleagues developed LACE-seq to globally profile RNA targets of RNA-binding proteins at single-nucleotide resolution in low-input cells or even single oocytes.

Ruibao Su
Li-Hua Fan
Yuanchao Xue
Research09 Jun 2021
Nature Cell Biology

Volume: 23, P: 664-675
Comparative analysis of the behavioral intention of potential wellness tourists in China and South Korea

Yang Zhou
Ligang Liu
Xiao Sun
ResearchOpen Access09 Aug 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-13
A joint-training topic model for social media texts

Simeng Qin
Mingli Zhang
Gang Li
ResearchOpen Access01 Mar 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-16
A cooperative optimization method for the layout of shared bicycle parking areas and delivery quantity

Hao Chen
Wenxian Wang
Ping Li
ResearchOpen Access20 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
Identifying subtypes and developing prognostic models based on N6-methyladenosine and immune microenvironment related genes in breast cancer

Lizhao Wang
Jianpeng Li
Ru Wang
ResearchOpen Access18 Jul 2024
Scientific Reports

Volume: 14, P: 1-19
Controllable degradation behavior of Mg-Sr-Y alloys for the bio-applications

Yingying Li
Yuan Yuan
Fusheng Pan
ResearchOpen Access27 May 2023
npj Materials Degradation

Volume: 7, P: 1-17
Exosomes derived from hypoxic glioma deliver miR-1246 and miR-10b-5p to normoxic glioma cells to promote migration and invasion

In this study, the authors reveal that the hypoxic microenvironment stimulates glioma to generate miR-1246- and miR-10b-5p-rich exosomes, which are delivered to normoxic glioma cells to promote their migration and invasion by targeting FRK and TFAP2A respectively. Treatment targeting the exosomes and microRNAs may impair the motility of gliomas, providing a novel direction for the development of antitumor therapy.

Mingyu Qian
Zihang Chen
Gang Li
Research14 Jan 2021
Laboratory Investigation

Volume: 101, P: 612-624
BEX1 supports the stemness of hepatoblastoma by facilitating Warburg effect in a PPARγ/PDK1 dependent manner

Qian Wang
Ning Liang
Gang Wang
Research15 Sept 2023
British Journal of Cancer

Volume: 129, P: 1477-1489
Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction

Jianye Xu
Jian Zhang
Gang Li
ResearchOpen Access07 Apr 2021
Cell Death & Disease

Volume: 12, P: 1-16
Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression

Ming Li
Hao Xu
Gang Li
ResearchOpen Access09 Sept 2022
Oncogene

Volume: 41, P: 4618-4632
Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis

Jian You
Bei Tao
Chuanhong Zhong
Research27 Dec 2022
Cancer Gene Therapy

Volume: 30, P: 683-693
Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma

Xiaoxiong Wang
Chen Shen
Shiguang Zhao
ResearchOpen Access09 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-15
USP1-regulated reciprocal differentiation of Th17 cells and Treg cells by deubiquitinating and stabilizing TAZ

Xiaotong Zhu
Peng Wang
Shengfeng Hu
Research05 Jan 2023
Cellular & Molecular Immunology

Volume: 20, P: 252-263
Transcription factor SNAI2 exerts pro-tumorigenic effects on glioma stem cells via PHLPP2-mediated Akt pathway

Lilei Peng
Jie Fu
Ligang Chen
ResearchOpen Access02 Jun 2022
Cell Death & Disease

Volume: 13, P: 1-9
Composition and temperature-dependent phase transition in miscible Mo_1−xW_xTe₂ single crystals

Yang-Yang Lv
Lin Cao
Yan-Feng Chen
ResearchOpen Access15 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway

Shulin Zhao
Boyan Li
Gang Li
Research17 Nov 2022
Oncogene

Volume: 42, P: 138-153
Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia

Qindong Guo
Yang Fan
Gang Li
ResearchOpen Access21 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-14
The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs

Yanhua Qi
Chuandi Jin
Gang Li
ResearchOpen Access02 May 2022
Cell Death & Disease

Volume: 13, P: 1-15
Nanotwinned and hierarchical nanotwinned metals: a review of experimental, computational and theoretical efforts

Ligang Sun
Xiaoqiao He
Jian Lu
ReviewsOpen Access05 Feb 2018
npj Computational Materials

Volume: 4, P: 1-18

Search

Abnormal activation of platelets and inflammation in smoking-induced rheumatoid arthritis is alleviated by 3,3′-diindolylmethane

Ultrasound-activated piezoelectric nanostickers for neural stem cell therapy of traumatic brain injury

Agricultural machinery could contribute 20% of total carbon and air pollutant emissions by 2050 and compromise carbon neutrality targets in China

Mitochondrial ATP synthase as a direct molecular target of chromium(III) to ameliorate hyperglycaemia stress

Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans

DNA methylation profiling to determine the primary sites of metastatic cancers using formalin-fixed paraffin-embedded tissues

Virtual elastography ultrasound via generative adversarial network for breast cancer diagnosis

Negative mixing enthalpy solid solutions deliver high strength and ductility

Telomeric TERB1–TRF1 interaction is crucial for male meiosis

Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation

Development of self-control in children aged 3 to 9 years: Perspective from a dual-systems model

YTHDF2 destabilizes m⁶A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

Statistical analysis of mutant allele frequency level of circulating cell-free DNA and blood cells in healthy individuals

Super square carbon nanotube network: a new promising water desalination membrane

Frame points attention convolution for deep learning on point cloud

Global profiling of RNA-binding protein target sites by LACE-seq

Comparative analysis of the behavioral intention of potential wellness tourists in China and South Korea

A joint-training topic model for social media texts

A cooperative optimization method for the layout of shared bicycle parking areas and delivery quantity

Identifying subtypes and developing prognostic models based on N6-methyladenosine and immune microenvironment related genes in breast cancer

Controllable degradation behavior of Mg-Sr-Y alloys for the bio-applications

Exosomes derived from hypoxic glioma deliver miR-1246 and miR-10b-5p to normoxic glioma cells to promote migration and invasion

BEX1 supports the stemness of hepatoblastoma by facilitating Warburg effect in a PPARγ/PDK1 dependent manner

Hypoxic glioma-derived exosomes promote M2-like macrophage polarization by enhancing autophagy induction

Tumor-derived exosomes deliver the tumor suppressor miR-3591-3p to induce M2 macrophage polarization and promote glioma progression

Transcription factor YY1 mediates self-renewal of glioblastoma stem cells through regulation of the SENP1/METTL3/MYC axis

Nitazoxanide, an antiprotozoal drug, inhibits late-stage autophagy and promotes ING1-induced cell cycle arrest in glioblastoma

USP1-regulated reciprocal differentiation of Th17 cells and Treg cells by deubiquitinating and stabilizing TAZ

Transcription factor SNAI2 exerts pro-tumorigenic effects on glioma stem cells via PHLPP2-mediated Akt pathway

Composition and temperature-dependent phase transition in miscible Mo_1−xW_xTe₂ single crystals

Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/ NF-κB pathway

Glioblastoma upregulates SUMOylation of hnRNP A2/B1 to eliminate the tumor suppressor miR-204-3p, accelerating angiogenesis under hypoxia

The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs

Nanotwinned and hierarchical nanotwinned metals: a review of experimental, computational and theoretical efforts

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