Coincidence detection is a fundamental neural operation, developed to an extreme in the computation of interaural time differences for sound localization. This study utilizes intracellular in vivo recordings and pharmacological manipulations in the medial superior olive of Mongolian gerbil to reveal that maximal coincidence is not just determined by the timing of synaptic inputs, but also by intrinsic neural properties.
- Tom P Franken
- Michael T Roberts
- Philip X Joris