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Showing 1–50 of 59 results

Advanced filters: Author: Luis F. Quintana Clear advanced filters

Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists

Variation in responses to bacterial and viral stimuli between Batwa rainforest hunter-gatherers and Bakiga agriculturalists from Uganda suggests population-level divergence under natural selection, with hunter-gatherers disproportionately showing signatures of positive selection.

Genelle F. Harrison
Joaquin Sanz
Luis B. Barreiro
Research29 Jul 2019
Nature Ecology & Evolution

Volume: 3, P: 1253-1264
Natural selection has driven population differentiation in modern humans

Luis B Barreiro
Guillaume Laval
Lluís Quintana-Murci
Research03 Feb 2008
Nature Genetics

Volume: 40, P: 340-345
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas

Indigenous populations, including in those in Mexico are underrepresented in genetic studies. Here, the authors perform a population genetics study of indigenous peoples in Mexico to explore demographic histories of the region in the context of geography and cultural influences.

Humberto García-Ortiz
Francisco Barajas-Olmos
Lorena Orozco
ResearchOpen Access12 Oct 2021
Nature Communications

Volume: 12, P: 1-12
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Mexican Biobank advances population and medical genomics of diverse ancestries

Nationwide genomic biobank in Mexico unravels demographic history and complex trait architecture from 6,057 individuals.

Mashaal Sohail
María J. Palma-Martínez
Andrés Moreno-Estrada
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 775-783
Legume abundance along successional and rainfall gradients in Neotropical forests

Data from 42 chronosequence sites show a geater abundance of legumes in seasonally dry forests than in wet forests, particularly during early secondary succession, probably owing to legumes’ nitrogen-fixing ability and reduced leaflet size.

Maga Gei
Danaë M. A. Rozendaal
Jennifer S. Powers
Research28 May 2018
Nature Ecology & Evolution

Volume: 2, P: 1104-1111
Androgen receptor CAG polymorphism and sporadic and early-onset prostate cancer among Mexican men

Rocío Gómez
Luisa Torres-Sánchez
Gino Noris
Research19 May 2016
Journal of Human Genetics

Volume: 61, P: 781-786
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

Analysis of HbA1c and FPG levels across 117 population-based studies demonstrates regional variation in prevalence of previously undiagnosed screen-detected diabetes using one or both measures and suggests that use of elevated FPG alone could underestimate diabetes prevalence in low- and middle-income countries.

Bin Zhou
Kate E. Sheffer
Majid Ezzati
ResearchOpen Access09 Nov 2023
Nature Medicine

Volume: 29, P: 2885-2901
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries

Average Nucleotide Identity (ANI) is a robust and useful measure to gauge genetic relatedness between two genomes. Here, the authors develop FastANI, a method to compute ANI using alignment-free approximate sequence mapping, and show 95% ANI is an accurate threshold for demarcating prokaryotic species by analyzing about 90,000 prokaryotic genomes.

Chirag Jain
Luis M. Rodriguez-R
Srinivas Aluru
ResearchOpen Access30 Nov 2018
Nature Communications

Volume: 9, P: 1-8
The epigenomic landscape of African rainforest hunter-gatherers and farmers

Genetic and environmental factors affect genome-wide patterns of epigenetic variation. Here, the authors show that while current habitat and historical lifestyle impact the methylome of rainforest hunter-gatherers and sedentary farmers, the biological functions affected and the degree of genetic control differ.

Maud Fagny
Etienne Patin
Lluis Quintana-Murci
ResearchOpen Access30 Nov 2015
Nature Communications

Volume: 6, P: 1-11
A new actinide sandwich on the menu

A berkelium metallocene complex was isolated and structurally characterized for the first time. These findings elevate our understanding of chemical bonding and inform on the future design of f-element quantum materials.

Luis M. Aguirre Quintana
Leander I. Held
Research Highlights02 Apr 2025
Nature Reviews Chemistry

Volume: 9, P: 282
Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Genotype and exome sequencing of 150,000 participants and whole-genome sequencing of 9,950 selected individuals recruited into the Mexico City Prospective Study constitute a valuable, publicly available resource of non-European sequencing data.

Andrey Ziyatdinov
Jason Torres
Roberto Tapia-Conyer
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 784-793
The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists

Agriculture emerged in West Africa 5,000 years ago but how this impacted the population of rainforest hunter-gatherers (RHGs) is unknown. Here, the authors show that modern-day RHG populations present up to 50% of farmer ancestry but admixture only occurred in the last 1,000 years.

Etienne Patin
Katherine J. Siddle
Lluís Quintana-Murci
Research04 Feb 2014
Nature Communications

Volume: 5, P: 1-10
Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection

Detailed insight into how the brain responds to Trypanosoma brucei infection is lacking. Here, single cell and spatial transcriptomics are integrated to characterise this response, identifying a unique crosstalk between microglia and plasma cells.

Juan F. Quintana
Praveena Chandrasegaran
Annette MacLeod
ResearchOpen Access30 Sept 2022
Nature Communications

Volume: 13, P: 1-19
Impact of SARS-CoV-2 infection therapies on the risk of venous thromboembolism and cardiovascular events from the SEMI-COVID-19 Registry

Crhistian-Mario Oblitas
Pablo Demelo-Rodríguez
Hector Meijide Míguez
ResearchOpen Access05 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Mapping routine measles vaccination in low- and middle-income countries

Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.

Alyssa N. Sbarra
Sam Rolfe
Jonathan F. Mosser
ResearchOpen Access16 Dec 2020
Nature

Volume: 589, P: 415-419
Mortality reduction in older COVID-19-patients hospitalized in Spain during the second pandemic wave from the SEMI-COVID-19 Registry

José-Manuel Casas-Rojo
Juan-Miguel Antón-Santos
Hector Meijide Míguez
ResearchOpen Access18 Oct 2023
Scientific Reports

Volume: 13, P: 1-18
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Inborn errors of the alternative NF-κB pathway in humans impair the development of AIRE-expressing medullary thymic epithelial cells, thereby underlying the production of autoantibodies against type I IFNs and predisposition to viral diseases

Tom Le Voyer
Audrey V. Parent
Anne Puel
ResearchOpen Access08 Nov 2023
Nature

Volume: 623, P: 803-813
From evolutionary genetics to human immunology: how selection shapes host defence genes

The recent increase in available human population genetic data is revealing signatures of selection at immunity-related genes. This Review discusses how studies of genome evolution are contributing to our understanding of how pathogens have shaped the human genome and immune response.

Luis B. Barreiro
Lluís Quintana-Murci
Reviews01 Dec 2009
Nature Reviews Genetics

Volume: 11, P: 17-30
The demographic history and mutational load of African hunter-gatherers and farmers

High-coverage exomes from 300 central African hunter-gatherers and farmers reveal recent population trends and gene flow, as well as insight into the effects these trends have had on their respective mutational loads.

Marie Lopez
Athanasios Kousathanas
Lluís Quintana-Murci
Research12 Mar 2018
Nature Ecology & Evolution

Volume: 2, P: 721-730
Reply to: Insufficient evidence for natural selection associated with the Black Death

Tauras P. Vilgalys
Jennifer Klunk
Luis B. Barreiro
Research19 Feb 2025
Nature

Volume: 638, P: E23-E29
Impact of severe acute kidney injury and chronic kidney disease on allogeneic hematopoietic cell transplant recipients: a retrospective single center analysis

Gonzalo Gutiérrez-García
Jesús Villarreal
Luis F. Quintana
Research26 Feb 2020
Bone Marrow Transplantation

Volume: 55, P: 1264-1271
A new functional JAZ degron sequence in strawberry JAZ1 revealed by structural and interaction studies on the COI1–JA-Ile/COR–JAZs complexes

Adrián Garrido-Bigotes
Felipe Valenzuela-Riffo
Carlos R. Figueroa
ResearchOpen Access09 Jul 2020
Scientific Reports

Volume: 10, P: 1-17
A novel mutation of the insulin-like 3 gene in patients with cryptorchidism

P. Canto
I. Escudero
J. P. Mendez
Research01 Feb 2003
Journal of Human Genetics

Volume: 48, P: 86-90
Eponyms are important tools for biologists in the Global South

Lou Jost
Mario Humberto Yanez-Muñoz
Marcelo Arana
Correspondence19 Jun 2023
Nature Ecology & Evolution

Volume: 7, P: 1164-1165
Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Andrey Ziyatdinov
Jason Torres
Roberto Tapia-Conyer
Amendments and CorrectionsOpen Access08 Feb 2024
Nature

Volume: 626, P: E18
Novel HLA class I associations with HIV-1 control in a unique genetically admixed population

Humberto Valenzuela-Ponce
Selma Alva-Hernández
Samuel Navarro-Álvarez
ResearchOpen Access17 Apr 2018
Scientific Reports

Volume: 8, P: 1-17
CXCL6 is an important paracrine factor in the pro-angiogenic human cardiac progenitor-like cell secretome

José Luis Torán
Susana Aguilar
Antonio Bernad
ResearchOpen Access02 Oct 2017
Scientific Reports

Volume: 7, P: 1-14
Interactions of Functionalized Multi-Wall Carbon Nanotubes with Giant Phospholipid Vesicles as Model Cellular Membrane System

Verónica Pérez-Luna
Carlos Moreno-Aguilar
Mildred Quintana
ResearchOpen Access20 Dec 2018
Scientific Reports

Volume: 8, P: 1-11
Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study

Luis Felipe Reyes
Alejandro Rodriguez
Neus Guasch
ResearchOpen Access21 Apr 2023
Scientific Reports

Volume: 13, P: 1-15
Periconceptional nutrition with spineless cactus (Opuntia ficus-indica) improves metabolomic profiles and pregnancy outcomes in sheep

César A. Rosales-Nieto
Maribel Rodríguez-Aguilar
Graeme B. Martin
ResearchOpen Access30 Mar 2021
Scientific Reports

Volume: 11, P: 1-14
Exploring the microbiome of two uterine sites in cows

Nilton Luis Murga Valderrama
Gleni Tatiana Segura Portocarrero
Rainer Marco Lopez Lapa
ResearchOpen Access31 Oct 2023
Scientific Reports

Volume: 13, P: 1-13
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14
Electrochemical sensor based on the synergy between Cucurbit[8]uril and 2D-MoS₂ for enhanced melatonin quantification

Rut Martínez-Moro
María del Pozo
Carmen Quintana
ResearchOpen Access27 Jun 2023
Scientific Reports

Volume: 13, P: 1-10
Pneumatophore CO₂ effluxes decrease with increased salinity in mangrove forests of Yucatan, Mexico

Julio A. Salas-Rabaza
Laura Yáñez-Espinosa
José Luis Andrade
ResearchOpen Access08 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Reactive astrocyte nomenclature, definitions, and future directions

Good–bad binary classifications fail to describe reactive astrocytes in CNS disorders. Here, 81 researchers reach consensus on widespread misconceptions and provide definitions and recommendations for future research on reactive astrocytes.

Carole Escartin
Elena Galea
Alexei Verkhratsky
Reviews15 Feb 2021
Nature Neuroscience

Volume: 24, P: 312-325
Circulating miR-323-3p is a biomarker for cardiomyopathy and an indicator of phenotypic variability in Friedreich’s ataxia patients

M. Seco-Cervera
D. González-Rodríguez
J. L. García-Giménez
ResearchOpen Access12 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
Prevalence of modifiable factors limiting treatment efficacy of poorly controlled asthma patients: EFIMERA observational study

Paula Ribó
Jesús Molina
Antonio Valero
ResearchOpen Access31 Jul 2020
npj Primary Care Respiratory Medicine

Volume: 30, P: 1-8
Maternal Work and Spontaneous Preterm Birth: A Multicenter Observational Study in Brazil

Mariana Buen
Eliana Amaral
Elvira A. O. Zanette
ResearchOpen Access16 Jun 2020
Scientific Reports

Volume: 10, P: 1-10
Human genetic and immunological determinants of critical COVID-19 pneumonia

The COVID Human Genetic Effort examines the molecular, cellular and immunological determinants of the various SARS-CoV-2-related disease manifestations by searching for causal errors of immunity.

Qian Zhang
Paul Bastard
Jean-Laurent Casanova
Reviews28 Jan 2022
Nature

Volume: 603, P: 587-598
Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis

Annalisa Roberti
Juan Ramon Tejedor
Mario F. Fraga
ResearchOpen Access22 May 2023
Scientific Reports

Volume: 13, P: 1-18
Cofilin dysregulation alters actin turnover in frataxin-deficient neurons

Diana C. Muñoz-Lasso
Belén Mollá
Pilar Gonzalez-Cabo
ResearchOpen Access23 Mar 2020
Scientific Reports

Volume: 10, P: 1-10
Whole genomic sequencing based genotyping reveals a specific X3 sublineage restricted to Mexico and related with multidrug resistance

Ana Cristina Jiménez-Ruano
Carlos Francisco Madrazo-Moya
Roberto Zenteno-Cuevas
ResearchOpen Access21 Jan 2021
Scientific Reports

Volume: 11, P: 1-9
Chemically synthesized chevron-like graphene nanoribbons for electrochemical sensors development: determination of epinephrine

Raquel Sainz
María del Pozo
Elena Casero
ResearchOpen Access03 Sept 2020
Scientific Reports

Volume: 10, P: 1-11
Machine learning-based model for prediction of clinical deterioration in hospitalized patients by COVID 19

Susana Garcia-Gutiérrez
Cristobal Esteban-Aizpiri
Ricardo Saenz de Madariaga
ResearchOpen Access02 May 2022
Scientific Reports

Volume: 12, P: 1-11
Addition of nocturnal pollinators modifies the structure of pollination networks

Yedra García
Luis Giménez-Benavides
Silvia Santamaría
ResearchOpen Access12 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
The first global deep-sea stable isotope assessment reveals the unique trophic ecology of Vampire Squid Vampyroteuthis infernalis (Cephalopoda)

Alexey V. Golikov
Filipe R. Ceia
José C. Xavier
ResearchOpen Access13 Dec 2019
Scientific Reports

Volume: 9, P: 1-13
Studying severe long COVID to understand post-infectious disorders beyond COVID-19

Petter Brodin
Giorgio Casari
Jean-Laurent Casanova
Correspondence05 Apr 2022
Nature Medicine

Volume: 28, P: 879-882
Novel SLC7A7 large rearrangements in lysinuric protein intolerance patients involving the same AluY repeat

Mariona Font-Llitjós
Benjamín Rodríguez-Santiago
Virginia Nunes
Research20 Aug 2008
European Journal of Human Genetics

Volume: 17, P: 71-79

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