Simulation-based materials informatics shows that when the detachment energies of the odd-numbered amino acids with –COOCH3 are high, and when the detachment energies of the even-numbered amino acids with –CH3 are high, the binding free energy between the peptide and PMMA resin becomes high. From this guideline, W, R, and E are found to be effective as odd-numbered amino acids, and W and R are found to be effective as even-numbered amino acids for strong adhesion to PMMA resin.
- Tomio Iwasaki
- Masashi Maruyama
- Takeshi Serizawa
