Nature Search

Useful Parameters To Predict the Eventual Mental Outcome of Hypothyroid Children

Jacqueline Glorieux
Manon Desjardins
Jean H Dussault
Research01 Jul 1988
Pediatric Research

Volume: 24, P: 6-8
cBAF generates subnucleosomes that expand OCT4 binding and function beyond DNA motifs at enhancers

Here, the authors show that the canonical BRG/BRM-associated factor (SWI/SNF) chromatin remodeler generates subnucleosomes containing 50–80 bp of DNA associated with the four core histones. These hemisome-like particles interact with OCT4 to expand its binding domain at enhancers.

Marina C. Nocente
Anida Mesihovic Karamitsos
Matthieu Gérard
Research02 Jul 2024
Nature Structural & Molecular Biology

Volume: 31, P: 1756-1768
Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma

Combined hepatocellular-cholangiocarcinomas (cHCC-CCA) are challenging to diagnose, as they exhibit features of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICCA). Here, the authors use deep learning to re-classify cHCC-CCA tumours into HCC or ICCA based on histopathology images.

Julien Calderaro
Narmin Ghaffari Laleh
Jakob Nikolas Kather
ResearchOpen Access14 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Multi-cohort machine learning identifies predictors of cognitive impairment in Parkinson’s disease

Rebecca Ting Jiin Loo
Lukas Pavelka
Lydia Yahia-Cherif
ResearchOpen Access26 Jul 2025
npj Digital Medicine

Volume: 8, P: 1-12
The transmission of pottery technology among prehistoric European hunter-gatherers

Analysis of pottery made and used by hunter-gatherers in northeastern Europe in the sixth millennium bc supports the existence of super-regional networks enabling cultural transmission long before the arrival of farming.

Ekaterina Dolbunova
Alexandre Lucquin
Oliver E. Craig
ResearchOpen Access22 Dec 2022
Nature Human Behaviour

Volume: 7, P: 171-183
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

Dinesh Aggarwal
Ben Warne
Ian G. Goodfellow
ResearchOpen Access08 Feb 2022
Nature Communications

Volume: 13, P: 1-16
Pivotal role of the endoplasmic reticulum stress-related XBP1s/miR-22/SIRT1 axis in acute myeloid leukemia apoptosis and response to chemotherapy

Céline Philippe
Manon Jaud
Christian Touriol
ResearchOpen Access22 Jun 2024
Leukemia

Volume: 38, P: 1764-1776
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

The Omicron variant evades vaccine-induced neutralization but also fails to form syncytia, shows reduced replication in human lung cells and preferentially uses a TMPRSS2-independent cell entry pathway, which may contribute to enhanced replication in cells of the upper airway. Altered fusion and cell entry characteristics are linked to distinct regions of the Omicron spike protein.

Brian J. Willett
Joe Grove
Emma C. Thomson
ResearchOpen Access07 Jul 2022
Nature Microbiology

Volume: 7, P: 1161-1179
Genomic reconstruction of the SARS-CoV-2 epidemic in England

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
ResearchOpen Access14 Oct 2021
Nature

Volume: 600, P: 506-511
Targeting cholangiocarcinoma cells by cold piezoelectric plasmas: in vitro efficacy and cellular mechanisms

Manon Soulier
Bouchra Lekbaby
Laura Fouassier
ResearchOpen Access04 Dec 2024
Scientific Reports

Volume: 14, P: 1-16
11,000 years of craniofacial and mandibular variation in Lower Nubia

Manon Galland
Denis P. Van Gerven
Ron Pinhasi
ResearchOpen Access09 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders

Comparing white matter disconnectivity across 12 psychiatric and neurological disorders, this study finds that the connections most important for global communication and network integration are particularly vulnerable to alterations across multiple brain disorders.

Siemon C. de Lange
Lianne H. Scholtens
Martijn P. van den Heuvel
Research05 Aug 2019
Nature Human Behaviour

Volume: 3, P: 988-998
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

The Alpha variant of SARS-CoV-2 outcompetes progenitor SARS-CoV-2 in upper respiratory tract replication competition in vivo.

Lorenz Ulrich
Nico Joel Halwe
Charaf Benarafa
ResearchOpen Access22 Dec 2021
Nature

Volume: 602, P: 307-313
Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

A yeast-based synthetic genomics platform is used to reconstruct and characterize large RNA viruses from synthetic DNA fragments; this technique will facilitate the rapid analysis of RNA viruses, such as SARS-CoV-2, during an outbreak.

Tran Thi Nhu Thao
Fabien Labroussaa
Volker Thiel
Research04 May 2020
Nature

Volume: 582, P: 561-565
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

A comprehensive characterisation of Omicron-BA.1 and VOC Delta in numerous in vitro and in vivo models uncovers the factors that led to its global dominance.

G. Tuba Barut
Nico Joel Halwe
Volker Thiel
ResearchOpen Access07 Oct 2022
Nature Communications

Volume: 13, P: 1-14
Galectin-3: a novel biomarker of glycogen storage disease type III

Lucille Rossiaud
Quentin Miagoux
Lucile Hoch
ResearchOpen Access14 Apr 2025
Cell Death Discovery

Volume: 11, P: 1-11
Sperm morphology and performance in relation to postmating prezygotic isolation in two recently diverged passerine species

Manon Poignet
Lucie Baránková
Radka Reifová
ResearchOpen Access24 Dec 2022
Scientific Reports

Volume: 12, P: 1-15
Analysis of DNA methylation in cancer: location revisited

Despite extensive research efforts, very few DNA methylation-based biomarkers have been implemented clinically. In this Perspective, the authors describe the importance of considering the genomic locations examined in determining the diagnostic or prognostic relevance of putative DNA methylation-based biomarkers.

Alexander Koch
Sophie C. Joosten
Manon van Engeland
Reviews17 Apr 2018
Nature Reviews Clinical Oncology

Volume: 15, P: 459-466
Expansion of the neurodevelopmental phenotype of individuals with EEF1A2 variants and genotype-phenotype study

Alix Paulet
Cavan Bennett-Ness
Lyse Ruaud
Research15 Feb 2024
European Journal of Human Genetics

Volume: 32, P: 1144-1149
Identification of common variants associated with human hippocampal and intracranial volumes

Paul Thompson and colleagues report a genome-wide association study for hippocampal, intracranial and total brain volume. They identify a locus at 12q24 associated with hippocampal volume and a locus at 12q14 associated with intracranial volume.

Jason L Stein
Sarah E Medland
Paul M Thompson
Research15 Apr 2012
Nature Genetics

Volume: 44, P: 552-561
A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

Manon Boul
Nassima Benzoubir
Bruno Le Pioufle
ResearchOpen Access07 Jul 2021
Scientific Reports

Volume: 11, P: 1-11
Genomic surveillance of Canadian airport wastewater samples allows early detection of emerging SARS-CoV-2 lineages

Alyssa K. Overton
Jennifer J. Knapp
Trevor C. Charles
ResearchOpen Access03 Nov 2024
Scientific Reports

Volume: 14, P: 1-17
Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders

Alexis E. Whitton
Poornima Kumar
Diego A. Pizzagalli
Research04 Jul 2023
Molecular Psychiatry

Volume: 28, P: 5272-5281
Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach

A high-content screening using a fluorescence readout has been used to identify pharmacological correctors of intracellularly-retained ABCB4 variants. The identified small molecules rescued canalicular targeting of ABCB4 variants.

Mounia Lakli
Julie Dumont
Thomas Falguières
ResearchOpen Access24 Jul 2024
Communications Biology

Volume: 7, P: 1-15
Evaluation of perinatal arterial ischemic stroke using noninvasive arterial spin labeling perfusion MRI

Jill B. De Vis
Esben T. Petersen
Manon J.N.L. Benders
Research24 Jun 2013
Pediatric Research

Volume: 74, P: 307-313
The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy

Meike Vogler
Yannick Braun
Martin JS Dyer
ReviewsOpen Access21 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-31
Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial

Manon L. M. Prins
Geert V. T. Roozen
Anna H. E. Roukens
ResearchOpen Access02 Jan 2024
npj Vaccines

Volume: 9, P: 1-10
Long-term effects of prenatal infection on the human brain: a prospective multimodal neuroimaging study

Anna Suleri
Charlotte Cecil
Veerle Bergink
ResearchOpen Access03 Oct 2023
Translational Psychiatry

Volume: 13, P: 1-9
Mammillary body injury in neonatal encephalopathy: a multicentre, retrospective study

Maarten. H. Lequin
Sylke. J. Steggerda
Seralynne D. Vann
ResearchOpen Access02 Mar 2021
Pediatric Research

Volume: 92, P: 174-179
Comprehensive reanalysis for CNVs in ES data from unsolved rare disease cases results in new diagnoses

German Demidov
Burcu Yaldiz
Steven Laurie
ResearchOpen Access26 Oct 2024
npj Genomic Medicine

Volume: 9, P: 1-24
The effect of genotypes and parent of origin on cancer risk and age of cancer development in PMS2 mutation carriers

Manon Suerink
Heleen M. van der Klift
Maartje Nielsen
Research25 Jun 2015
Genetics in Medicine

Volume: 18, P: 405-409
Phase-Contrast Magnetic Resonance Angiography Measurements of Global Cerebral Blood Flow in the Neonate

Manon J N L Benders
Jeroen Hendrikse
Floris Groenendaal
Research01 Jun 2011
Pediatric Research

Volume: 69, P: 544-547
Patterns of distribution, population genetics and ecological requirements of field-occurring resistant and susceptible Pseudosuccinea columella snails to Fasciola hepatica in Cuba

Annia Alba
Antonio A. Vázquez
Benjamin Gourbal
ResearchOpen Access07 Oct 2019
Scientific Reports

Volume: 9, P: 1-15
Preterm infants with isolated cerebellar hemorrhage show bilateral cortical alterations at term equivalent age

Aicha B. C. Dijkshoorn
Elise Turk
Jeroen Dudink
ResearchOpen Access24 Mar 2020
Scientific Reports

Volume: 10, P: 1-12
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Punctate White Matter Lesions Associated With Altered Brain Development And Adverse Motor Outcome In Preterm Infants

Nora Tusor
Manon J. Benders
A. David Edwards
ResearchOpen Access16 Oct 2017
Scientific Reports

Volume: 7, P: 1-9
Mobilise-D insights to estimate real-world walking speed in multiple conditions with a wearable device

Cameron Kirk
Arne Küderle
Linda Van Gelder
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-23
Basics, benefits, and pitfalls of pupillometers assessing visual function

Manon Philibert
Dan Milea
Reviews27 May 2024
Eye

Volume: 38, P: 2415-2421

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