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Showing 1–4 of 4 results
Advanced filters: Author: Miling Wang Clear advanced filters

  • mRNA translation efficiency is regulated in response to stimuli. Here the authors employ mass spectrometry analysis of ribosome fractions and show that under hypoxia, oxygen-sensitive RNA binding proteins enhance the translation efficiency of glycolysis pathway transcripts.

    • J. J. David Ho
    • Nathan C. Balukoff
    • Stephen Lee
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • Translatome remodelling controls stress-adaptive protein output. Here the authors reveal that in response to stimuli, eIF5A functions as a pH-regulated translation factor that responds to fermentation-induced acidosis affecting cellular metabolism.

    • Nathan C. Balukoff
    • J. J. David Ho
    • Stephen Lee
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • RNA polymerase II has an unexpected function in the nucleolus, helping to drive the expression of ribosomal RNA and to protect nucleolar structure through a mechanism involving triplex R-loop structures.

    • Karan J. Abraham
    • Negin Khosraviani
    • Karim Mekhail
    Research
    Nature
    Volume: 585, P: 298-302