Nature Search

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

Analysis of a large ancient genome dataset shows that genetic risk for multiple sclerosis rose in steppe pastoralists, providing insight into how genetic ancestry from the Neolithic and Bronze Age has shaped modern immune responses.

William Barrie
Yaoling Yang
Eske Willerslev
ResearchOpen Access10 Jan 2024
Nature

Volume: 625, P: 321-328
Measurement of the inelastic proton–proton cross-section at √s=7 TeV with the ATLAS detector

The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access06 Sept 2011
Nature Communications

Volume: 2, P: 1-14
Spectrum of the Venus day sky

V. I. Moroz
Yu. M. Golovin
N. F. San'ko
Research20 Mar 1980
Nature

Volume: 284, P: 243-244
Evidence for general instability of past climate from a 250-kyr ice-core record

W. Dansgaard
S. J. Johnsen
G. Bond
Research15 Jul 1993
Nature

Volume: 364, P: 218-220
T-cell recognition of a chimaeric class II/class I MHC molecule and the role of L3T4

Hana Golding
James McCluskey
Alfred Singer
Research03 Oct 1985
Nature

Volume: 317, P: 425-427
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Cecilia Lindgren and colleagues report results of a large-scale genome-wide association study for waist-to-hip ratio, a measure of body fat distribution. They identify 13 new loci associated with this trait, several of which show stronger effects in women than in men.

Iris M Heid
Anne U Jackson
Cecilia M Lindgren
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 949-960
Anhedonia in the shadow of chronic social defeat stress, or When the experimental context matters

Natalia P. Bondar
Irina L. Kovalenko
Natalia N. Kudryavtseva
ResearchOpen Access19 Dec 2008
Nature Precedings

P: 1
Regional patterns of human cortex development correlate with underlying neurobiology

The neurobiology of human brain development and aging is hard to study in vivo. The authors report on distinct spatial associations between brain morphology and cellular as well as molecular brain properties throughout neurodevelopment and aging.

Leon D. Lotter
Amin Saberi
Juergen Dukart
ResearchOpen Access12 Sept 2024
Nature Communications

Volume: 15, P: 1-21
MR1 presents microbial vitamin B metabolites to MAIT cells

The structure of the major histocompatibility complex (MHC)-class-I-like molecule MR1 in complex with a vitamin B9 derivative is determined; metabolites of vitamin B2 are shown to activate MR1-restricted mucosal-associated invariant T cells, implicating them in microbial immunosurveillance.

Lars Kjer-Nielsen
Onisha Patel
James McCluskey
Research10 Oct 2012
Nature

Volume: 491, P: 717-723
Anthropogenic modification of forests means only 40% of remaining forests have high ecosystem integrity

Mapping and quantifying degree of forest modification is critical to conserve and manage forests. Here the authors propose a new quantitative metric for landscape integrity and apply it to a global forest map, showing that less than half of the world’s forest cover has high integrity, most of which is outside nationally designed protected areas.

H. S. Grantham
A. Duncan
J. E. M. Watson
ResearchOpen Access08 Dec 2020
Nature Communications

Volume: 11, P: 1-10
Topological network alignment uncovers biological function and phylogeny

Oleksii Kuchaiev
Tijana Milenkovic
Natasa Przulj
ResearchOpen Access17 Dec 2009
Nature Precedings

P: 1
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Genome-wide association analyses of two oral glucose tolerance test-derived measures of postprandial insulin resistance discover ten new loci. Functional characterization identifies nine candidate genes implicated in the regulation of GLUT4.

Alice Williamson
Dougall M. Norris
Claudia Langenberg
Research08 Jun 2023
Nature Genetics

Volume: 55, P: 973-983
Phase transitions in random circuit sampling

By implementing random circuit sampling, experimental and theoretical results establish the existence of transitions to a stable, computationally complex phase that is reachable with current quantum processors.

A. Morvan
B. Villalonga
S. Boixo
ResearchOpen Access09 Oct 2024
Nature

Volume: 634, P: 328-333
Structure sensitivity in the iron single-crystal catalysed synthesis of ammonia

N. D. Spencer
R. C. Schoonmaker
G. A. Somorjai
Research17 Dec 1981
Nature

Volume: 294, P: 643-644
Soluble urokinase receptor released from human carcinoma cells: A plasma parameter for xenograft tumour studies

C Holst-Hansen
M J A G Hamers
R W Stephens
ResearchOpen Access27 Aug 1999
British Journal of Cancer

Volume: 81, P: 203-211
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

This study uses gene expression predictors for the dorsolateral prefrontal cortex and other brain regions to perform a transcriptomic imputation analysis of schizophrenia, identifying 413 genic associations across 13 brain regions and 36 significantly enriched pathways.

Laura M. Huckins
Amanda Dobbyn
Eli A. Stahl
Research25 Mar 2019
Nature Genetics

Volume: 51, P: 659-674
Does C₆₀ have a liquid phase?

M. H. J. Hagen
E. J. Meijer
H. N. W. Lekkerkerker
Research30 Sept 1993
Nature

Volume: 365, P: 425-426
Mapping the diversity of land uses following deforestation across Africa

Robert N. Masolele
Diego Marcos
Martin Herold
ResearchOpen Access19 Jan 2024
Scientific Reports

Volume: 14, P: 1-16
Synergistic Toxicity and Carcinogenicity of ‘Freons’ and Piperonyl Butoxide

SAMUEL S. EPSTEIN
S. JOSHI
N. MANTEL
Research01 Apr 1967
Nature

Volume: 214, P: 526-528
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization

K. Bajou
A. Noël
J.M. Foidart
Research01 Aug 1998
Nature Medicine

Volume: 4, P: 923-928
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Genome-wide analyses using fetal and parental genotypes identify 40 independent associations influencing placental weight and highlight the role of the fetus in preeclampsia risk and placental growth regulation via insulin signaling.

Robin N. Beaumont
Christopher Flatley
Pål R. Njølstad
ResearchOpen Access05 Oct 2023
Nature Genetics

Volume: 55, P: 1807-1819
Observational evidence for Criegee intermediate oligomerization reactions relevant to aerosol formation in the troposphere

Measurements of Criegee intermediate oligomerization signatures in the Amazon rainforest indicate that the role of Criegee intermediate chemistry in the composition of Earth’s troposphere has been underestimated.

R. L. Caravan
T. J. Bannan
C. J. Percival
Research05 Mar 2024
Nature Geoscience

Volume: 17, P: 219-226
Iodine Contents of Normal Human Eye Tissues

F. B. DE JORGE
N. KARA JOSÉ
Research01 Apr 1967
Nature

Volume: 214, P: 491-492
A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

Ten years after the discovery of the Higgs boson, the ATLAS experiment at CERN probes its kinematic properties with a significantly larger dataset from 2015–2018 and provides further insights on its interaction with other known particles.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access04 Jul 2022
Nature

Volume: 607, P: 52-59
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

It is now shown that tumour-associated macrophages recruited early during tumour evolution stimulate stromal fibroblasts to express collagen crosslinking enzymes and that the stromal expression, particularly of lysyl hydroxylase 2, can predict survival in a patient cohort.

Ori Maller
Allison P. Drain
Valerie M. Weaver
Research30 Nov 2020
Nature Materials

Volume: 20, P: 548-559
The Three Kingdoms of Nature

E. G. C.
Research16 Mar 1876
Nature

Volume: 13, P: 386
Young peridotitic diamonds from the Mir kimberlite pipe

N. Shimizu
N. V. Sobolev
Research01 Jun 1995
Nature

Volume: 375, P: 394-397
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

An expanded GWAS of birth weight and subsequent analysis using structural equation modeling and Mendelian randomization decomposes maternal and fetal genetic contributions and causal links between birth weight, blood pressure and glycemic traits.

Nicole M. Warrington
Robin N. Beaumont
Rachel M. Freathy
Research01 May 2019
Nature Genetics

Volume: 51, P: 804-814
Carbon isotope compositions of fluid inclusions in charnockites from southern India

D. H. Jackson
D. P. Mattey
N. B. W. Harris
Research12 May 1988
Nature

Volume: 333, P: 167-170
A 150,000-year climatic record from Antarctic ice

C. Lorius
J. Jouzel
V. M. Kotlyakov
Research01 Aug 1985
Nature

Volume: 316, P: 591-596
Additive-free MXene inks and direct printing of micro-supercapacitors

Printing functional inks is attractive for applications in electrochemical energy storage and smart electronics, among others. Here the authors report highly concentrated, additive-free, aqueous and organic MXene-based inks that can be used for high-resolution extrusion and inkjet printing.

Chuanfang (John) Zhang
Lorcan McKeon
Valeria Nicolosi
ResearchOpen Access17 Apr 2019
Nature Communications

Volume: 10, P: 1-9
Electron Donation and Acceptance by Carcinogenic Compounds

A. C. ALLISON
T. NASH
Research23 Feb 1963
Nature

Volume: 197, P: 758-763
Estimating the Qualities of a Photographic Plate

T. THORNE BAKER
Research21 Feb 1925
Nature

Volume: 115, P: 264-265
Copper and Cobalt in Nitrogen Fixation

E. G. HALLSWORTH
S. B. WILSON
E. A. N. GREENWOOD
Research02 Jul 1960
Nature

Volume: 187, P: 79-80
Purification-based quantum error mitigation of pair-correlated electron simulations

It is hoped that simulations of molecules and materials will provide a near-term application of quantum computers. A study of the performance of error mitigation highlights the obstacles to scaling up these calculations to practically useful sizes.

T. E. O’Brien
G. Anselmetti
N. C. Rubin
ResearchOpen Access12 Oct 2023
Nature Physics

Volume: 19, P: 1787-1792
Chronic immune stimulation is required for Moloney leukaemia virus-induced lymphomas

John C. Lee
James N. Ihle
Research29 Jan 1981
Nature

Volume: 289, P: 407-409
Observation of magnetic islands in tokamak plasmas during the suppression of edge-localized modes

The suppression of edge-localized modes in tokamak plasmas is crucial to prevent them from damaging the walls of the chamber. Now experiments confirm the role that magnetic islands play in suppressing these detrimental modes.

Matthias Willensdorfer
Verena Mitterauer
S. Zoletnik
ResearchOpen Access28 Oct 2024
Nature Physics

Volume: 20, P: 1980-1988
Mechanics of the Respiratory System during Passive Exhalation in Preterm Lambs

Peter Richardson
Scott Jarriel
Thomas N Hansen
Research01 Nov 1989
Pediatric Research

Volume: 26, P: 425-428
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Environmental influences during prenatal development may have implications for health and disease later in life. Here, Czamara et al. assess DNA methylation in cord blood from new-born under various models including environmental and genetic effects individually and their additive or interaction effects.

Darina Czamara
Gökçen Eraslan
Elisabeth B. Binder
ResearchOpen Access11 Jun 2019
Nature Communications

Volume: 10, P: 1-18
Alfvén waves generated by an inverted plasma energy distribution

W. J. HUGHES
D. J. SOUTHWOOD
J. N. BARFIELD
Research07 Sept 1978
Nature

Volume: 275, P: 43-45
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

The genetic basis of atopic dermatitis is not fully understood. Here, the authors find 91 genetic loci associated with atopic dermatitis in a GWAS of >1million individuals, which highlight the importance of systemic immune regulation.

Ashley Budu-Aggrey
Anna Kilanowski
Lavinia Paternoster
ResearchOpen Access04 Oct 2023
Nature Communications

Volume: 14, P: 1-18
A Pleistocene lacustrine episode in southeastern Libya

C. Gaven
C. Hillaire-Marcel
N. Petit-Maire
Research12 Mar 1981
Nature

Volume: 290, P: 131-133
A New Reversible Solid-State Transformation in Iron–Nickel Alloys in the Invar Range of Compositions

N. I. ANANTHANARAYANAN
R. J. PEAVLER
Research09 Dec 1961
Nature

Volume: 192, P: 962-963
Killed Listeria monocytogenes vaccine becomes protective on addition of polyanions

C. VAN DER MEER
F. M. A. HOFHUIS
J. M. N. WILLERS
Research01 Oct 1977
Nature

Volume: 269, P: 594-595
Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

Here the authors show in a model of ALS that motor neurons receive stronger inhibitory synaptic inputs than slow motor neurons, and disease progression is associated with specific loss of inhibitory synapses onto fast motor neurons.

Ilary Allodi
Roser Montañana-Rosell
Ole Kiehn
ResearchOpen Access31 May 2021
Nature Communications

Volume: 12, P: 1-18
Rare and low-frequency coding variants alter human adult height

Data from over 700,000 individuals reveal the identity of 83 sequence variants that affect human height, implicating new candidate genes and pathways as being involved in growth.

Eirini Marouli
Mariaelisa Graff
Guillaume Lettre
Research01 Feb 2017
Nature

Volume: 542, P: 186-190
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Combining 32 genome-wide association studies with high-density imputation provides a comprehensive view of the genetic contribution to type 2 diabetes in individuals of European ancestry with respect to locus discovery, causal-variant resolution, and mechanistic insight.

Anubha Mahajan
Daniel Taliun
Mark I. McCarthy
Research08 Oct 2018
Nature Genetics

Volume: 50, P: 1505-1513
A composite bolometer as a charged-particle spectrometer

N. Coron
G. Dambier
O. Testard
Research07 Mar 1985
Nature

Volume: 314, P: 75-76
Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF

DCAF5 has a quality-control function for SWI/SNF complexes and promotes the degradation of incompletely assembled SWI/SNF complexes in the absence of SMARCB1.

Sandi Radko-Juettner
Hong Yue
Charles W. M. Roberts
Research27 Mar 2024
Nature

Volume: 628, P: 442-449

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