Human immunodeficiency virus (HIV)-associated gut microbiome dysbiosis correlates with systemic immunodeficiency and opportunistic gut infections. Faecal microbiome transplantation from people living with HIV with high peripheral CD4+ T cell counts improved intestinal immunity and protection against Cryptosporidium parvum in mice.
- Stavros Bashiardes
- Melina Heinemann
- Eran Elinav