Hepatorenal syndrome, which is characterized by functional renal failure secondary to renal vasoconstriction in the absence of underlying kidney pathology, is a feared complication of cirrhosis. This Review focuses on the pathogenesis, clinical features, and diagnosis of hepatorenal syndrome. The authors also consider current management options, which include liver transplantation, pharmacologic therapies, transjugular intrahepatic portosystemic shunt placement and albumin dialysis.
- Andrés Cárdenas
- Pere Ginès