Nature Search

Manufacture and use of hook-tools by New Caledonian crows

Gavin R. Hunt
Research18 Jan 1996
Nature

Volume: 379, P: 249-251
Evidence for the Random Aggregation of Sub-units to produce Multiple Forms of Lactate Dehydrogenase in the Brains of Rat and Man

R. G. SPECTOR
D. C. WATTS
Research14 Oct 1967
Nature

Volume: 216, P: 154-156
Bedtime insulin injections in the diabetic child

F R J Hinde
D I Johnston
Research01 Nov 1984
Pediatric Research

Volume: 18, P: 1220
Increasing the efficiency and precision of prime editing with guide RNA pairs

An approach relying on guide RNA pairs encoding the same edits in both sense and antisense DNA strands is developed to improve the editing capability of prime editing in human cells.

Yuan Zhuang
Jiangle Liu
Chengqi Yi
Research28 Oct 2021
Nature Chemical Biology

Volume: 18, P: 29-37
Vibrational Spectra and Structure of the Tricyanomethanide Ion C(CN)⁻₃

D. A. LONG
R. A. G. CARRINGTON
R. B. GRAVENOR
Research27 Oct 1962
Nature

Volume: 196, P: 371-372
Observation of antiferromagnetic order in a quasicrystal

Quasicrystals lack translational symmetry but display rotational order. Whether antiferromagnetic order can exist in quasicrystals has been unclear. Now, long-range antiferromagnetic order is shown in the icosahedral quasicrystal Au₅₆In_28.5Eu_15.5.

R. Tamura
T. Abe
T. J. Sato
ResearchOpen Access14 Apr 2025
Nature Physics

Volume: 21, P: 974-979
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies

MultiSTAAR provides a general and flexible statistical framework for functionally informed multi-trait rare variant analysis of biobank-scale sequencing studies by jointly analyzing multiple traits and incorporating annotation information.

Xihao Li
Han Chen
Xihong Lin
Research07 Feb 2025
Nature Computational Science

Volume: 5, P: 125-143
Small-molecule inhibition of APT1 affects Ras localization and signaling

Reversible palmitoylation controls the localization and signaling of Ras. Development of a potent and specific small molecule inhibitor of the thioesterase APT1 reveals that this enzyme depalmitoylates Ras in cells. Inhibition of APT1 led to redistribution and altered activity of HRas, NRas and an oncogenic mutant Ras.

Frank J Dekker
Oliver Rocks
Herbert Waldmann
Research25 Apr 2010
Nature Chemical Biology

Volume: 6, P: 449-456
The quasi-crystalline phase in the Mg—Al—Zn system

T. Rajasekharan
D. Akhtar
K. Muraleedharan
Research07 Aug 1986
Nature

Volume: 322, P: 528-530
Kinetin, as a Mitotic Stimulant in Triturus viridescens

W. B. BUCKLEY
E. R. WITKUS
C. A. BERGER
Research23 Jun 1962
Nature

Volume: 194, P: 1200-1201
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Analyses of genome and exome sequencing data identify rare coding and structural variants associated with atrial fibrillation and highlight genetic links between atrial fibrillation and cardiomyopathies.

Seung Hoan Choi
Sean J. Jurgens
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 548-562
Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria

An attractive route for carbon-negative synthesis of biochemical products is the reverse β-oxidation pathway coupled to the Wood-Ljungdahl pathway. Here the authors use a high-throughput in vitro prototyping workflow to screen 762 unique pathway combinations using cell-free extracts tailored for r-BOX to identify enzyme sets for enhanced product selectivity.

Bastian Vögeli
Luca Schulz
Michael C. Jewett
ResearchOpen Access01 Jun 2022
Nature Communications

Volume: 13, P: 1-10
Virus-induced gene editing free from tissue culture

Recent advances have brought virus-induced gene editing closer to achieving its promise to simplify and democratize plant gene editing by weaning it from its dependence on tissue-culture-based transformation.

Abraham R. Steinberger
Daniel F. Voytas
Reviews25 Jun 2025
Nature Plants

Volume: 11, P: 1241-1251
Efficient gene editing in induced pluripotent stem cells enabled by an inducible adenine base editor with tunable expression

Krittika Nandy
Dinesh Babu
Shaji R. Velayudhan
ResearchOpen Access11 Dec 2023
Scientific Reports

Volume: 13, P: 1-15
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

Solid organ transplant recipients are at increased risk of infectious disease and have unique molecular pathophysiology. Here the authors use host-microbe profiling to assess SARS-CoV-2 infection and immunity in solid organ transplant recipients, showing enhanced viral abundance, impaired clearance, and increased expression of innate immunity genes.

Harry Pickering
Joanna Schaenman
Charles R. Langelier
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-16
Autophagy of the m⁶A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis

RNA m6A demethylase FTO has oncogenic roles in cancers. Here the authors show that chronic low-level exposure of arsenic inhibits autophagic degradation of FTO, leading to FTO stabilisation and reduced m6A RNA methylation in keratinocytes and its subsequent malignant transformation.

Yan-Hong Cui
Seungwon Yang
Yu-Ying He
ResearchOpen Access12 Apr 2021
Nature Communications

Volume: 12, P: 1-19
Assessing confidence in Pliocene sea surface temperatures to evaluate predictive models

Sea-surface-temperature proxy data for a period of natural climate warming during the Pliocene are used in this study to show how palaeoclimatic data can help ‘ground truth’ numerical models, increasing the confidence in these same models for projecting future climate.

Harry J. Dowsett
Marci M. Robinson
Christina R. Riesselman
Research18 Mar 2012
Nature Climate Change

Volume: 2, P: 365-371
High cell density alters the ratio of type III to I collagen synthesis by fibroblasts

SHIGETO ABE
BEAT U. STEINMANN
GEORGE R. MARTIN
Research01 May 1979
Nature

Volume: 279, P: 442-444
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
An integrated genomic and transcriptomic survey of mucormycosis-causing fungi

Fungi of the order Mucorales can cause life-threatening infections. Here, Chibucos et al. present genomic and transcriptomic analyses of a diverse set of Mucorales fungi, shedding light on their evolution and identifying potential therapeutic targets in the pathogens and the host.

Marcus C. Chibucos
Sameh Soliman
Vincent M. Bruno
ResearchOpen Access22 Jul 2016
Nature Communications

Volume: 7, P: 1-11
Large-scale profiling of protein palmitoylation in mammalian cells

S-palmitoylation is a protein post-translational modification involved in trafficking, compartmentalization and membrane-tethering of various proteins. A palmitic acid analog, 17-octadecynoic acid, serves as a metabolically incorporated bioorthogonal click chemistry probe for detecting S-palmitoylated human proteins by mass spectrometry or in-gel fluorescence.

Brent R Martin
Benjamin F Cravatt
Research11 Jan 2009
Nature Methods

Volume: 6, P: 135-138
Crystal structure of trp represser/operator complex at atomic resolution

Z. Otwinowski
R. W. Schevitz
P. B. Sigler
Research22 Sept 1988
Nature

Volume: 335, P: 321-329
Probing the tunable multi-cone band structure in Bernal bilayer graphene

Bernal-stacked bilayer graphene (BLG) has been extensively studied due to its tunable band gap and emerging electronic properties, but its low-energy band structure remains debated. Here, the authors report magnetotransport measurements of Bernal BLG, showing evidence of four Dirac cones and electrically induced topological transitions.

Anna M. Seiler
Nils Jacobsen
R. Thomas Weitz
ResearchOpen Access11 Apr 2024
Nature Communications

Volume: 15, P: 1-9
A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Prime-editing mouse models enable the study of specific cancer mutations in vivo.

Zackery A. Ely
Nicolas Mathey-Andrews
Tyler Jacks
Research11 May 2023
Nature Biotechnology

Volume: 42, P: 424-436
Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias

Susan J. Coker
J. R. Parratt
I. J. Zeitlin
Research28 May 1981
Nature

Volume: 291, P: 323-324
CRISPR/Cas9-mediated base editors and their prospects for mitochondrial genome engineering

Shahin Eghbalsaied
Clancy Lawler
Stephen Frankenberg
Reviews04 Jan 2024
Gene Therapy

Volume: 31, P: 209-223
Extraordinarily high biomass benthic community on Southern Ocean seamounts

R. E. Thresher
J. Adkins
A. Williams
ResearchOpen Access18 Oct 2011
Scientific Reports

Volume: 1, P: 1-5
Carbonate record of temporal change in oxygen fugacity and gaseous species in asteroid Ryugu

The asteroid Ryugu experienced aqueous alteration under changing temperature and redox conditions, according to an isotopic analysis of secondary calcite and dolomite grains in samples from Ryugu obtained by the Hayabusa2 spacecraft.

Wataru Fujiya
Noriyuki Kawasaki
Hisayoshi Yurimoto
Research10 Jul 2023
Nature Geoscience

Volume: 16, P: 675-682
A phase I/II study of a hypoxic cell radiosensitizer KU-2285 in combination with intraoperative radiotherapy

Y Shibamoto
G Ohshio
M Abe
Research01 Dec 1997
British Journal of Cancer

Volume: 76, P: 1474-1479
Increased production of cosmogenic ¹⁰Be during the Last Glacial Maximum

Yong Lao
R. F. Anderson
W. Wolfli
Research18 Jun 1992
Nature

Volume: 357, P: 576-578
Orexin signaling modulates synchronized excitation in the sublaterodorsal tegmental nucleus to stabilize REM sleep

Orexin signaling is provided by diffusely distributed fibers and involved in different brain circuits that orchestrate sleep and wakefulness states. Here, the authors show that a proportion of orexin neurons project to the sublaterodorsal tegmental nucleus and exhibit rapid eye movement (REM) sleep-related actions.

Hui Feng
Si-Yi Wen
Jun Zhang
ResearchOpen Access21 Jul 2020
Nature Communications

Volume: 11, P: 1-16
Cytotoxic T lymphocyte mediated lysis without release of serine esterase

Hanne L. Ostergaard
Kevin P. Kane
William R. Clark
Research05 Nov 1987
Nature

Volume: 330, P: 71-72
Novel sex differences in linkage values and meiotic chromosome behaviour in a marsupial

J. H. Bennett
D. L. Hayman
R. M. Hope
Research04 Sept 1986
Nature

Volume: 323, P: 59-60
Contribution of Ryugu-like material to Earth’s volatile inventory by Cu and Zn isotopic analysis

A comparison of copper and zinc isotopic measurements between the Ryugu samples and various carbonaceous chondrites excludes any genetic link between the two except for the CI (Ivuna-type) chondrites. Ryugu-like material might have accounted for ~5% of Earth’s mass.

Marine Paquet
Frederic Moynier
Hisayoshi Yurimoto
Research12 Dec 2022
Nature Astronomy

Volume: 7, P: 182-189
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo

Delivery of prime editors in vivo is improved using virus-like particles.

Meirui An
Aditya Raguram
David R. Liu
ResearchOpen Access08 Jan 2024
Nature Biotechnology

Volume: 42, P: 1526-1537
Behaviour Patterns in Chromatin-positive Klinefelter's Syndrome of Sheep

R. KILGOUR
A. N. BRUERE
Research03 Jan 1970
Nature

Volume: 225, P: 71-72
Gene therapy for cardiac arrhythmias

In this Review, Ackerman and colleagues describe the rationale for gene therapy to treat cardiac arrhythmias; discuss advantages and disadvantages of gene silencing, replacement and editing technologies; summarize vector modalities and delivery approaches; present examples of gene therapy strategies used for atrial and ventricular arrhythmias; and highlight the current challenges and limitations in the gene therapy field.

Sahej Bains
John R. Giudicessi
Michael J. Ackerman
Reviews23 May 2025
Nature Reviews Cardiology

P: 1-16
Observation of vibrational overtones by single-molecule resonant photodissociation

Studying the spectra of molecules typically requires large samples, which can be difficult to achieve for hard-to-generate ions. Here, the authors obtain spectra from single CaH⁺molecules in a three-ion Columbic crystal, observing new molecular transitions.

Ncamiso B. Khanyile
Gang Shu
Kenneth R. Brown
ResearchOpen Access22 Jul 2015
Nature Communications

Volume: 6, P: 1-4
Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Reengineering polyketide synthase encoding genes to produce analogues of natural products can be slow and low-yielding. Here the authors use accelerated evolution to recombine the gene cluster for rapid production of rapamycin-related products.

Aleksandra Wlodek
Steve G. Kendrew
Matthew A. Gregory
ResearchOpen Access31 Oct 2017
Nature Communications

Volume: 8, P: 1-10
Heterogeneous Earth’s mantle drilled at an embryonic ocean

Integrated Ocean Discovery Program Expedition 402 drilled two in-situ long mantle sections in the Tyrrhenian Sea, revealing that retention of large quantities of melts at mantle levels delayed the birth of an ocean basin.

Alessio Sanfilippo
Ashutosh Pandey
Nevio Zitellini
ResearchOpen Access27 Feb 2025
Nature Communications

Volume: 16, P: 1-11
Thermally altered subsurface material of asteroid (162173) Ryugu

Hayabusa2 created an artificial crater on Ryugu to analyse the subsurficial material of the asteroid. Results show that the subsurface is more hydrated than the surface. It experienced alteration processes that can be traced back to Ryugu’s parent body.

K. Kitazato
R. E. Milliken
Y. Tsuda
Research04 Jan 2021
Nature Astronomy

Volume: 5, P: 246-250
Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis

CD47 is a promising new target in cancer immunotherapy and recently the pro-phagocytic signal SLAMF7 has been shown to have a crucial role in phagocytosis induced by CD47-blocking antibody in hematological tumors. In this study, the authors demonstrate that SLAMF7 expressed by cancer cells is not required for phagocytosis suggesting that, in contrast to CD47 expression, SLAMF7 should not be used as selection criterion for CD47-targeted therapy.

Yuan He
Renee Bouwstra
Edwin Bremer
ResearchOpen Access01 Feb 2019
Nature Communications

Volume: 10, P: 1-8
Electron Spin Resonance Spectrum of NH⁺₂SO⁻₃

N. M. ATHERTON
J. R. MORTON
Research15 Jan 1966
Nature

Volume: 209, P: 294-295
A dynamic sequence of visual processing initiated by gaze shifts

Parker et al. recorded neural activity in V1 of freely moving mice and freely gazing marmosets. In both species, neurons respond to gaze shifts in a temporal sequence, such that new visual input is processed in a ‘coarse’ to ‘fine’ manner.

Philip R. L. Parker
Dylan M. Martins
Cristopher M. Niell
Research23 Nov 2023
Nature Neuroscience

Volume: 26, P: 2192-2202
Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys

Michael Murphey-Corb
Louis N. Martin
Ronald C. Montelaro
Research22 May 1986
Nature

Volume: 321, P: 435-437
Cobalt in north-east Pacific waters

G. A. Knauer
J. H. Martin
R. M. Gordon
Research06 May 1982
Nature

Volume: 297, P: 49-51
Efficient prime editing in mouse brain, liver and heart with dual AAVs

Prime editors are efficiently delivered to mouse organs with AAV vectors.

Jessie R. Davis
Samagya Banskota
David R. Liu
ResearchOpen Access04 May 2023
Nature Biotechnology

Volume: 42, P: 253-264
Plecotus austriacus in Dorset

R. E. STEBBINGS
Research17 Apr 1965
Nature

Volume: 206, P: 314-315
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

Using data from a single time point, passenger-approximated clonal expansion rate (PACER) estimates the fitness of common driver mutations that lead to clonal haematopoiesis and identifies TCL1A activation as a mediator of clonal expansion.

Joshua S. Weinstock
Jayakrishnan Gopakumar
Siddhartha Jaiswal
Research12 Apr 2023
Nature

Volume: 616, P: 755-763
Relationship between measles and canine distemper viruses determined by delayed type hypersensitivity reactions in dogs

A. L. BROWN
R. E. McCARTHY
Research01 Mar 1974
Nature

Volume: 248, P: 344-345

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